Sodyum Bikarbonat %8.4 IV Infusion Icin Solution Iceren Ampul

Sodium Bicarbonate 8.4% IV Infusion Solution Ampoule is a medical solution widely used in healthcare settings, particularly in Turkey. It is available in ampoules designed for intravenous administration.

Dosage form

Pack size

Potency

%8.4 10X10Ml

Manufacturer

Origin

Generic Name (Ingredient)

Bir Ampul 0, 84 G Sodyum Bikarbonat Icerir.

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Description

Composition

Each 10 ml ampoule contains 840 mg (84 mg/ml) of sodium bicarbonate as the active ingredient. The solution also includes injection-grade water as an auxiliary substance.

Usage

This solution is intended exclusively for intravenous use. It is primarily used after cardiac arrest to normalize the body’s pH levels. During cardiac arrest, the body produces an excessive amount of acid, and Sodyum Bikarbonat %8.4 IV injection helps to neutralize this increased acid.

Contraindications

Do not use Sodyum Bikarbonat %8.4 IV Infusion Solution Ampoule if you have:

  • Kidney failure
  • Metabolic or respiratory acid-base imbalance (metabolic or respiratory alkalosis)
  • High blood pressure (hypertension)
  • Edema
  • Congestive heart failure
  • A history of kidney stones with potassium deficiency or low serum calcium levels
  • Respiratory insufficiency (hypoventilation)
  • Chloride deficiency or high serum sodium levels

Special Considerations

Use this solution with caution if you are:

  • Pregnant
  • Breastfeeding

Storage

The specific storage conditions for this solution are not detailed in the sources. It is advisable to follow the manufacturer’s instructions or consult a healthcare professional for proper storage guidelines.

Administration of Sodyum Bikarbonat %8.4 IV Infusion Solution Ampoule

Sodium Bicarbonate 8.4% IV Infusion Solution Ampoule is administered intravenously. The following steps outline its administration:

Preparation

The solution is hypertonic, with a high concentration of sodium. It should be prepared under close medical supervision.

Method of Administration

The solution is administered by slow direct IV injection or continuous infusion. Typically, it is diluted in 5% glucose before administration.

Precautions

Certain substances should not be added to the sodium bicarbonate solution, including penicillins, chloramphenicol, aspirin, atropine, calcium, insulin, and vitamins.

Effects of Administration

The high sodium concentration limits the distribution of the solution to the extracellular fluid (ECF). The hypertonic nature of the solution draws water out of cells until the ECF and intracellular fluid (ICF) tonicities are equal. The increase in ECF volume will be greater than the volume of solution administered.

Alternative Administration Methods

While typically administered intravenously, there are alternative methods for administering Sodyum Bikarbonat %8.4 IV Infusion Solution Ampoule in certain situations.

Bolus Intravenous Injection

In emergencies, the solution can be given as a bolus injection, directly into the vein in one go.

Intermittent Intravenous Infusion

The solution can also be administered using an electronically controlled infusion device, slowly infusing the solution into the vein over time.

Dilution

The 8.4% solution is hypertonic and may need to be diluted with 5% glucose if required.

Alternatives to Sodyum Bikarbonat %8.4 IV

Alternatives to sodium bicarbonate for counteracting the negative cardiovascular effects of acidaemia include carbicarb, dichloroacetate, and Tris/THAM.

Potential Side Effects

The administration of Sodium Bicarbonate 8.4% IV Infusion Solution Ampoule can have several potential side effects. These may vary depending on individual health conditions and the dosage administered.

Fluid and Electrolyte Imbalance

Intravenous administration can cause fluid and/or solute overloading, resulting in dilution of serum electrolyte concentrations, overhydration, congested states, or pulmonary edema.

Venous Irritation and Tissue Necrosis

Hypertonic solutions may cause venous irritation. Extravasation, or leakage of the solution into surrounding tissue, may lead to tissue necrosis.

Sodium Retention

In patients with diminished renal function, administration of sodium-containing solutions may result in sodium retention.

Shock and Loss of Extremity

Accidental intra-arterial administration of the 8.4% preparation may cause shock or lead to the loss of an extremity.

Benefits

Sodyum Bikarbonat %8.4 IVInfusion Solution Ampoule offers several benefits:

Reduction of Acid in Blood and Urine

The primary benefit is the reduction of acid levels in the blood and urine. High acid levels can cause symptoms such as headaches, weakness, tiredness, fast breathing, and abnormal heart rate. Conditions causing high acid levels include diabetes, hepatitis, heart and kidney problems, shock, severe dehydration or diarrhea, Addison’s disease, and malnutrition.

Emergency Treatment of Acute Hyponatremia

Sodium bicarbonate solution is occasionally recommended for emergency treatment of acute hyponatremia, particularly when there is a perceived benefit of alkalosis.

Speeding Up Removal of Certain Substances

It is used to expedite the removal of certain substances from the body in cases of specific types of poisoning.

Cardiac Arrest

The solution is used after cardiac arrest to restore the body’s pH to normal.

Metabolic Acidosis

In cases of metabolic acidosis, sodium bicarbonate is administered over 3 to 4 hours in an amount appropriate to the body base deficit.

Patient Populations Benefiting

Several patient populations can benefit from Sodyum Bikarbonat %8.4 IV Infusion Solution Ampoule:

Patients with Metabolic Acidosis

Patients with metabolic acidosis, a condition characterized by excessive acid in body fluids, can benefit from this solution.

Patients with High Acid Levels

Patients with high acid levels in the blood, which can cause various symptoms, can benefit from this solution.

Patients with Certain Types of Poisoning

The solution is used to speed up the removal of certain substances from the body in cases of specific types of poisoning.

Patients with Cardiac Arrest

The solution is used after cardiac arrest to restore the body’s pH to normal.

Patients with Acute Hyponatremia

Sodium bicarbonate solution is occasionally recommended for emergency treatment of acute hyponatremia, particularly when there is a perceived benefit of alkalosis.

Patients with Hyperkalemia

In the context of metabolic acidosis, increasing the pH shifts potassium into cells, thereby improving hyperkalemia.


Table: Key Information on Sodyum Bikarbonat %8.4 IV Infusion Solution Ampoule

Category Details
Side Effects Fluid and electrolyte imbalance, venous irritation, tissue necrosis, sodium retention, shock, and loss of extremity
Dosage Administered intravenously, typically diluted in 5% glucose, dosage varies based on condition and patient needs
Benefits Reduces acid in blood and urine, emergency treatment of acute hyponatremia, speeds up removal of certain substances, used after cardiac arrest, treats metabolic acidosis
Usage Intravenous use only, primarily after cardiac arrest to normalize pH levels
Precautions Contraindicated in kidney failure, metabolic or respiratory alkalosis, hypertension, edema, congestive heart failure, history of kidney stones with potassium deficiency or low serum calcium levels, respiratory insufficiency, chloride deficiency, or high serum sodium levels
Special Considerations Use with caution if pregnant or breastfeeding
Alternative Administration Bolus intravenous injection, intermittent intravenous infusion, dilution with 5% glucose
Alternatives Carbicarb, dichloroacetate, Tris/THAM

This comprehensive overview of Sodium Bicarbonate 8.4% IV Infusion Solution Ampoule provides essential information for healthcare professionals and patients, ensuring safe and effective use of the solution.

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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.

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