Fraxiparine Injection 3800 IU/0.4Ml

Fraxiparine Injection 3800 IU/0.4 mL, also known as Nadroparin, is a low molecular weight heparin (LMWH) anticoagulant widely used in the prevention and treatment of various thromboembolic disorders. This comprehensive guide aims to provide medical professionals with an in-depth understanding of Fraxiparine, its uses, administration, and potential side effects.

Dosage form

Pack size


3800 Iu/0.4Ml 2X0.4Ml



Generic Name (Ingredient)

0.4 Ml Injectable Sterile Solution Nadroparin Calcium (Inn) 3800 Iu Axa (Equivalent To 1000 Icu Axa) (1 Icu Axa Is Equivalent To 0.38 Iu Axa.)

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Fraxiparine Injection 3800 IU/0.4 mL is a prefilled syringe containing 0.4 mL of Nadroparin, a potent anticoagulant agent. It works by inhibiting the formation of blood clots and preventing the growth of existing ones, ensuring smooth blood flow throughout the body.

Mechanism of Action

Nadroparin, the active ingredient in Fraxiparine, belongs to the class of low molecular weight heparins (LMWHs). It exerts its anticoagulant effect by enhancing the activity of antithrombin III, a natural inhibitor of blood clotting factors. By binding to antithrombin III, Nadroparin potentiates its ability to inactivate clotting factors, thereby preventing the formation of harmful blood clots.

Indications and Uses

Fraxiparine Injection 3800 IU/0.4 mL is indicated for the following conditions:

Prevention of Venous Thromboembolism (VTE)

  • Deep Vein Thrombosis (DVT) prophylaxis in patients undergoing orthopedic surgery, such as hip or knee replacement
  • DVT prophylaxis in medical patients at risk of thromboembolic complications due to restricted mobility during acute illness

Treatment of Venous Thromboembolism (VTE)

  • Treatment of acute DVT
  • Treatment of acute pulmonary embolism (PE)

Unstable Angina and Myocardial Infarction

  • Adjunctive treatment in patients with unstable angina or non-Q-wave myocardial infarction


  • Prevention of clotting during hemodialysis sessions

Dosage and Administration

The dosage of Fraxiparine Injection 3800 IU/0.4 mL varies depending on the indication and individual patient factors, such as body weight, age, and renal function. It is essential to follow the prescribed dosage and administration guidelines provided by the healthcare professional.

Subcutaneous Injection

Fraxiparine is administered via subcutaneous injection, typically into the abdomen or thigh area. Healthcare professionals should provide proper instructions on self-injection techniques to patients who require long-term treatment.

Potential Side Effects

Like all medications, Fraxiparine Injection 3800 IU/0.4 mL may cause side effects in some patients. The most common side effects include:

  • Injection site reactions (pain, bruising, redness)
  • Bleeding (nosebleeds, gum bleeding, easy bruising)
  • Hematoma formation at the injection site
  • Elevated liver enzymes

Patients should be monitored closely for signs of bleeding or other adverse reactions, and any concerns should be promptly reported to their healthcare provider.

Contraindications and Precautions

Fraxiparine Injection 3800 IU/0.4 mL should be used with caution in patients with the following conditions:

  • Active bleeding or increased risk of bleeding
  • Recent surgery or trauma
  • Severe renal impairment
  • Uncontrolled hypertension
  • Pregnancy and breastfeeding (consult with a healthcare professional)

Drug Interactions

Fraxiparine may interact with other medications, including anticoagulants, antiplatelet agents, and non-steroidal anti-inflammatory drugs (NSAIDs). Healthcare professionals should review the patient’s medication list and adjust the dosage or monitoring as necessary.

Monitoring and Follow-up

Regular monitoring of coagulation parameters, such as activated partial thromboplastin time (aPTT) or anti-Xa levels, may be necessary in certain patient populations or clinical situations. Follow-up visits and assessments should be scheduled to evaluate the effectiveness and safety of the treatment.

Table: Key Information about Fraxiparine Injection 3800 IU/0.4 mL

Aspect Details
Active Ingredient Nadroparin
Dosage Form Prefilled syringe (0.4 mL)
Strength 3800 IU anti-Xa
Indications Prevention and treatment of VTE, unstable angina, myocardial infarction, hemodialysis
Administration Subcutaneous injection
Common Side Effects Injection site reactions, bleeding, hematoma, elevated liver enzymes
Contraindications Active bleeding, recent surgery/trauma, severe renal impairment
Monitoring Coagulation parameters (aPTT, anti-Xa levels)


Fraxiparine Injection 3800 IU/0.4 mL is a valuable anticoagulant medication used in various clinical settings for the prevention and treatment of thromboembolic disorders. Healthcare professionals should carefully evaluate the risks and benefits, monitor for potential side effects, and provide appropriate patient education to ensure safe and effective use of this medication.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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