Zoprotec Film Tablet 30 Mg

Zoprotec, a pharmaceutical marvel, harnesses the potency of zofenopril calcium, classified as an angiotensin-converting enzyme (ACE) inhibitor. ACE inhibitors play a pivotal role in hypertension management. This guide unveils the intricacies of Zoprotec, offering insights into its composition, applications, and safety considerations.

Dosage form

Pack size


30 Mg



Generic Name (Ingredient)

Zofenopril Calcium (Equivalent To 28.7 Mg Zofenoprile) 30 Mg

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Each Zoprotec Plus 30/12.5 mg film-coated tablet encapsulates 30 mg of zofenopril calcium, equivalent to 28.7 mg of zofenopril, and 12.5 mg of hydrochlorothiazide. The formulation integrates excipients like microcrystalline cellulose, lactose monohydrate (derived from cow’s milk), corn starch, hypromellose, colloidal anhydrous silica, magnesium stearate, titanium dioxide (E171), red iron oxide (E172), macrogol 400, and macrogol 6000. These elements work in harmony, enhancing the medication’s effectiveness.


Zoprotec emerges as a stalwart in the battle against high blood pressure (hypertension). Beyond this pivotal role, it steps into the arena of acute myocardial infarction, extending its benefits to patients exhibiting symptoms of heart failure and those not treated with thrombolytic therapy.

Dosage and Administration

Oral administration makes Zoprotec accessible and convenient. The tablets, oblong and film-coated, boast divisibility, allowing for precise dosing. Packaging options include packs of 14 and 28 film tablets, ensuring a tailored approach to treatment.


While Zoprotec stands as a beacon of hope for many, it is crucial to heed contraindications. Patients with hypersensitivity to zofenopril calcium, hydrochlorothiazide, sulfonamide derivatives (like hydrochlorothiazide), or a history of severe allergy symptoms triggered by ACE inhibitors (such as captopril or enalapril) must exercise caution. Pregnancy, as well as hereditary/idiopathic angioedema or previous angioedema linked to ACE inhibitor therapy, warrants avoidance of this medication.

Zoprotec Side Effects

As with any medication, Zoprotec can induce side effects, although they tend to be rare, mild, and transient. Potential side effects encompass:

Common Side Effects (may affect up to 1 in 10 people):

  • Dizziness
  • Headache
  • Fatigue
  • Rash

Uncommon Side Effects (may affect up to 1 in 100 people):

  • Nausea
  • Diarrhea
  • Abdominal pain
  • Muscle cramps

Rare Side Effects (may affect up to 1 in 1,000 people):

  • Vomiting
  • Itching
  • Urticaria (hives)
  • Angioedema (swelling of the face, lips, tongue, and/or throat that may cause difficulty in breathing or swallowing)

Very Rare Side Effects (may affect up to 1 in 10,000 people):

  • Hepatitis (inflammation of the liver)
  • Jaundice (yellowing of the skin or eyes)
  • Elevation of liver enzymes

Not Known (frequency cannot be estimated from the available data):

  • Decrease in red and white blood cells
  • Decrease in platelets
  • Allergic reactions

This list, while informative, does not encompass all possible side effects. In the event of any adverse reactions while taking Zoprotec, swift consultation with a healthcare provider or pharmacist is paramount.

Pregnancy and Breastfeeding

Pregnancy: Zoprotec is contraindicated during pregnancy. Expectant mothers or those planning pregnancy should engage in a comprehensive discussion with their healthcare provider to weigh potential risks and benefits.

Breastfeeding: Specific information regarding Zoprotec’s impact on breastfeeding is not readily available. However, considering that many medications can traverse into breast milk, consultation with a healthcare provider is essential before introducing any new medication during breastfeeding. Their guidance will be tailored to the medication’s specifics and your individual health status.


The dosage of Zoprotec is individualized, contingent on the disease’s etiology and the severity of clinical manifestations. Oral administration allows for flexibility, with a maximum daily dose of 2.4 g for adults. In cases like rheumatoid arthritis, dosages can extend to 0.8 g three times daily. For osteoarthrosis and ankylosing spondylitis, dosages typically range from 0.4 to 0.6 g, administered 3 to 4 times daily.

It’s imperative to underscore that these are general guidelines, and exact dosages may fluctuate based on individual patient needs. Collaboration with a healthcare provider remains paramount for precise dosage recommendations.


Zoprotec Film Tablet 30 Mg, enriched with zofenopril calcium, emerges as a potent contender in the realm of hypertension management and acute myocardial infarction treatment. Its well-rounded approach, user-friendly dosing, and comprehensive safety considerations position it as a valuable tool in healthcare. However, adherence to healthcare provider guidance is essential to ensure safe and effective treatment. This comprehensive guide serves as an informative resource but should complement, not replace, the counsel of healthcare professionals.

At a glance

Property Details
Active Ingredient Zofenopril Calcium
Angiotensin-Converting Enzyme (ACE) Inhibitor Used primarily for lowering blood pressure
Composition Each Zoprotec Plus 30/12.5 mg film-coated tablet contains 30 mg of zofenopril calcium and 12.5 mg of hydrochlorothiazide1. Excipients include microcrystalline cellulose, lactose monohydrate, corn starch, and more.
Indications Treatment of high blood pressure (hypertension)12, and heart attack (acute myocardial infarction) in certain cases.
Dosage and Administration Oral administration1. Tablets are divisible and available in packs of 14 and 28 film tablets.
Contraindications Hypersensitivity to zofenopril calcium, hydrochlorothiazide, sulfonamide derivatives, previous ACE inhibitor hypersensitivity reactions, pregnancy, angioedema.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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