Description
Zoprotec, a medication embodying Zofenopril Calcium, stands as a stalwart in the realm of hypertension treatment and myocardial infarction management. Let’s unravel its intricacies.
Aspect | Details |
---|---|
Active Ingredient | Zofenopril Calcium |
Composition | Each Zoprotec 15 mg film-coated tablet contains 15 mg of Zofenopril Calcium, equivalent to 14.3 mg of Zofenopril. Excipients include microcrystalline cellulose, lactose monohydrate (sourced from cow’s milk), and others. |
Indications | Zoprotec is an Angiotensin-Converting Enzyme (ACE) inhibitor used for hypertension treatment and in the acute phase of myocardial infarction in hemodynamically stable patients not receiving thrombolytic therapy. |
Dosage and Admin. | Dosage is individualized, taken orally after a meal. |
Zoprotec Dosage
The dosage of Zoprotec is meticulously tailored to the unique clinical manifestations of each patient. This individualization ensures optimal therapeutic outcomes. It is imperative to administer this medication orally, and it is recommended to do so after a meal, facilitating its absorption.
Interactions
Zoprotec, while efficacious, is not without its potential interactions. Vigilance is paramount when it comes to concomitant use with potassium-sparing diuretics, potassium supplements, lithium, anesthetics, narcotics, and antipsychotics. Healthcare providers should be well-informed about all medications and supplements their patients are taking to mitigate the risk of adverse reactions.
Contraindications and Cautions
Zoprotec is unsuitable for individuals displaying hypersensitivity to Zofenopril Calcium or other ACE inhibitors. Moreover, it is contraindicated in cases of severe liver problems, renal artery stenosis, pregnancy, and conditions that increase the risk of angioedema. These contraindications underscore the importance of a thorough medical assessment before prescribing it.
Storage Guidelines
Ensuring the efficacy and safety of Zoprotec necessitates meticulous storage. A temperature not exceeding 25°C is recommended, and controlled room temperature is acceptable if specific storage requirements are absent. Adequate lighting, ventilation, sanitation, and security are prerequisites in the storage area.
A quarantine area for outdated, damaged, or deteriorated tablets is a prudent measure.
The Mechanism of Action
Central to Zoprotec’s efficacy is its active ingredient, Zofenopril Calcium. As an ACE inhibitor, it suppresses the plasma renin-angiotensin-aldosterone system, leading to reduced vasopressor activity and aldosterone secretion. This culminates in vasodilation, lowered blood pressure, and enhanced cardiac function. It is crucial to understand that Zofenopril Calcium undergoes metabolism in the body to produce zofenoprilat, the active drug responsible for these effects.
Conclusion
Zoprotec Film Tablet 15 mg, fortified with Zofenopril Calcium, serves as a cornerstone in the management of hypertension and acute myocardial infarction. Its individualized dosing, meticulous precautions, and profound mechanism of action underscore its significance in modern medicine. However, prescribing and usage should always be guided by a healthcare professional, ensuring tailored care for each patient’s unique medical profile
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