Terbisil Cream (Terbizil)

The cream should be avoided on the mucous membrane of the eyes, nose, and mouth. When they get into the eyes, they must be washed with plenty of water and, if necessary, consult with a doctor. During treatment, general hygiene rules should be followed to avoid re-infection through underwear and shoes. The clinical effect is usually observed from the first days of treatment.

Irregular use or premature termination of treatment leads to a relapse of the disease. In the case when, after 2 weeks of treatment, improvement is not observed, the diagnosis and sensitivity of the pathogen to the drug should be checked.

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Description

Anti-fungal drug for outdoor use

Release form, Composition, and Packaging

Outdoor cream 1% white or almost white, with a slight smell of almonds.

 

1 g
Terbinafine hydrochloride 10 mg,
Which corresponds to the content of terbinafine 8.8 mg

 

Auxiliary substances: Sodium hydroxide – 1.2 mg, gasoline alcohol – 10 mg, monostearat – 19 mg, cetylpalmitate – 20 mg, cetyl alcohol – 40 mg, cetostearyl alcohol <TA%, stearyl alcohol 40%) – 40 mg, polysorbat 60 – 61 mg, isopropylmiristat – 80 mg, water purified – 718.8 mg.

15 g – aluminum tubes (1) – cardboard packs.

Terbisil Cream Indications

— fungal skin infections caused by dermatophytes Trichophyton (T. rubrum, T. mentagrophytes, T. verrucosum, T. violaceum, T. interdigitale, T. tonsurans), Microsporum canis and gypseum, Epidermophyton floccosum;

— skin infections caused by yeast-like mushrooms, mainly Candida (e.g. Candida albicans);

— multi-colored (chop) lichen Pityriasis Versicolor caused by Pityrosporum orbiculare (Malassezia furfur).

Dosing mode

For outdoor use. The duration of treatment depends on the nature and severity of the disease.

Adults and Children

After preliminary purification and drying of the affected surface, a therapeutic cream 1 – 2 t / day is applied to it with a thin layer, slightly rubbing it into the affected and adjacent healthy areas of the skin. In places of physiological folds of leather (areas under the mammary glands, inter-finger spaces, inter-sit and inguinal areas) it is desirable to cover gauze after applying cream, in particular, at night.

For dermatomycosis of the body and legs: cream is used 1 – 2 times/day; treatment duration is 1 – 2 weeks.

At dermatomycosis: apply 1 – 2 times/day; treatment duration is 2 – 4 weeks.

Skin candidiasis cream can be used up to 2 times/day; the duration of treatment is 1 – 2 weeks.

Multi-colored lichen cream can be used up to 2 times/day; the course of treatment is 2 weeks.

Pharmacological effect

Terbinafine belongs to the group of allylamines, and has a wide range of antifungal effects. Active in relation to dermatophytes TrichophytonMicrosporum, and Epidermophyton, as well as yeast mushrooms, mainly Candida albicans, as well as in relation to Pityrosporum ovale – the causative agent of multi-colored lichen (Pityriasis Versicolor). Depending on the type of mushroom, the mushrooms of the genus Candida and their mycelial forms have fungicidal or fungistatic effects.

Inhibits mushrooms – epoxidase and violates the early stage of sterol biosynthesis, leading to an ergosterol deficiency, accumulation in the good cell, and dead cell. The fungicidal effect is observed already at low concentrations of the drug and is manifested in the effect on the synthesis and formation of the mushroom membrane.

The – epoxidase is not related to the P450 cytochrome system (CYP450), so terbinafine does not affect the metabolism of hormones and drugs whose metabolism is associated with CYP450.

Terbisil Cream Side effect

In rare cases, redness of the skin, itching, or burning sensation, requiring termination of treatment, occurs at the place of application of the cream.

Terbisil Spray
Terbisil Spray

Contraindications

  • Breastfeeding period;
  • Hypersensitivity to which – or of the components of the drug.
  • With caution: During pregnancy, in childhood (due to the lack of sufficient clinical experience).

Pregnancy and lactation

During pregnancy, the drug can only be used if the intended benefit for the mother exceeds the potential risk for the fetus. Terbisil Cream Contradicted during breastfeeding.  If it’s necessary and the treatment with Terbisil Cream during lactation should resolve the issue of stopping breastfeeding.

Application for liver function disorders

Data on the use of Terbisil Cream in patients with impaired liver function is not provided.

Application for kidney function disorders

Data on the use of Terbisil Cream in patients with impaired renal function is not provided.

Elder use

Assigning the drug to elderly patients does not require dosage correction. and is prescribed in the same mode.

Application for children

Use with caution in childhood (Due to the lack of sufficient clinical experience).

Overdose

To date, Terbisil Cream has not reported overdose cases. If the cream is accidentally ingested, nausea, loss of appetite, pain in the upper abdomen, and diarrhea are possible.

Treatment: activated charcoal, and if necessary, carry out symptomatic therapy.

Drug Interaction

The interaction of Terbisil Cream (Terbizil cream) with other drugs is unknown.

Storage conditions:

Store at a temperature of 15-30 ° C out of the reach of children.

Best before date

5 years.

Do not use it after the expiry date stated on the package.

Terbizil cream

Terbizil cream manufacturer: GEDEON RICHTER Plc. (Hungary)

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Additional information

Dosage form

Pack size

Potency

%1 30G

Manufacturer

Origin

Generic Name (Ingredient)

1 G Of Cream Contains 10 Mg Of Terbinafine Hydrochloride.

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Cyberchondria

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According to Wikipedia, cyberchondria is a mental disorder consisting in the desire to independently make a diagnosis based on the symptoms of diseases described on Internet sites.

Why you can't look for symptoms on the Internet

If diagnoses could be made simply from a textbook or an article on a website, we would all be doctors and treat ourselves. Nothing can replace the experience and knowledge of specially trained people. As in any field, in medicine there are unscrupulous specialists, differences of opinion, inaccurate diagnoses and incorrect test results.

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