Terbisil Tablet 250 Mg

Description

How it Works: Inhibiting Squalene Monooxygenase

Terbisil contains the active ingredient terbinafine, which works by inhibiting the enzyme squalene monooxygenase, also known as squalene epoxidase. This enzyme is responsible for the conversion of squalene to 2,3-oxydosqualene, a critical step in the synthesis of ergosterol, a key component of the fungal cell membrane. Terbinafine’s inhibition of this enzyme leads to decreased ergosterol production, which would normally be incorporated into the cell wall, and accumulation of squalene. The generation of a large number of squalene-containing vesicles in the cytoplasm may leach other lipids away from, and further weaken, the fungal cell wall.

Usage: Treating Various Fungal Infections

Terbisil cream is primarily used to treat interdigital tinea pedis, commonly known as athlete’s foot, tinea cruris or jock itch, tinea corporis or ringworm due to susceptible organisms, and planter tinea pedis or mocasin type due to Trichophyton spp. Terbisil tablets are used to treat onychomycosis of the toenail or fingernail due to dermatophytes and non-dermatophyte fungi.

Dosage: Follow Your Doctor’s Prescription

The recommended oral dosage for Terbisil 250 mg tablet is once daily for 2 to 12 weeks depending on the severity of the infection. For fingernail onychomycosis, the recommended dosage is 250 mg once daily for 6 weeks, while for toenail onychomycosis, it is Terbisil 250 mg once daily for 12 weeks. Always follow your doctor’s prescription and do not exceed the recommended dosage.

Side Effects: Minor and Manageable

Like any medication, Terbisil can cause side effects. However, most of these side effects are minor and manageable. Some common side effects include stomach upset, diarrhea, nausea, headache, muscle pain, joint pain, and skin rash. To prevent sunburn, it is important to avoid exposure to bright sunlight or tanning beds while taking this medication.

Precautions: Consult Your Doctor Before Taking Terbisil

It is essential to consult your doctor before taking Terbisil, particularly if you are pregnant or breastfeeding, as it is not known if it is safe for use during these times. Patients taking oral Terbisil should undergo liver function tests before treatment to reduce the risk of liver injury. Avoid exposure to bright sunlight or tanning beds while taking this medication, as it can cause itching, redness, and severe sunburn. If you are using Terbisil cream, avoid contact with the eyes. In case of accidental contact with the eyes, rinse them thoroughly with running water. Keep this cream out of reach of children. In the event of an allergic reaction, remove the cream and interrupt the treatment immediately.

Conclusion

Terbisil is a reliable antifungal medication that effectively treats various fungal infections of the skin, hair, and nails. By inhibiting squalene monooxygenase, it prevents the synthesis of ergosterol, an essential component of the fungal cell wall. This leads to weakening and death of the fungal cell, providing relief from infections.