Terbisil Tablet 250 Mg
Terbisil is a widely used antifungal medication available in both tablet and cream form. It is known to effectively treat various fungal infections of the skin, hair, and nails. Here, we will discuss how it works, its uses, dosage, side effects, and precautions.
| Manufacturer | |
|---|---|
| Origin | |
| Generic Name (Ingredient) | 1 Tablet; Terbinafine Hydrochloride Equivalent To 125 Mg Terbinafine Base. |
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Description
How it Works: Inhibiting Squalene Monooxygenase
Terbisil contains the active ingredient terbinafine, which works by inhibiting the enzyme squalene monooxygenase, also known as squalene epoxidase. This enzyme is responsible for the conversion of squalene to 2,3-oxydosqualene, a critical step in the synthesis of ergosterol, a key component of the fungal cell membrane. Terbinafine’s inhibition of this enzyme leads to decreased ergosterol production, which would normally be incorporated into the cell wall, and accumulation of squalene. The generation of a large number of squalene-containing vesicles in the cytoplasm may leach other lipids away from, and further weaken, the fungal cell wall.
Usage: Treating Various Fungal Infections
Terbisil cream is primarily used to treat interdigital tinea pedis, commonly known as athlete’s foot, tinea cruris or jock itch, tinea corporis or ringworm due to susceptible organisms, and planter tinea pedis or mocasin type due to Trichophyton spp. Terbisil tablets are used to treat onychomycosis of the toenail or fingernail due to dermatophytes and non-dermatophyte fungi.
Dosage: Follow Your Doctor’s Prescription
The recommended oral dosage for Terbisil 250 mg tablet is once daily for 2 to 12 weeks depending on the severity of the infection. For fingernail onychomycosis, the recommended dosage is 250 mg once daily for 6 weeks, while for toenail onychomycosis, it is Terbisil 250 mg once daily for 12 weeks. Always follow your doctor’s prescription and do not exceed the recommended dosage.
Side Effects: Minor and Manageable
Like any medication, Terbisil can cause side effects. However, most of these side effects are minor and manageable. Some common side effects include stomach upset, diarrhea, nausea, headache, muscle pain, joint pain, and skin rash. To prevent sunburn, it is important to avoid exposure to bright sunlight or tanning beds while taking this medication.
Precautions: Consult Your Doctor Before Taking Terbisil
It is essential to consult your doctor before taking Terbisil, particularly if you are pregnant or breastfeeding, as it is not known if it is safe for use during these times. Patients taking oral Terbisil should undergo liver function tests before treatment to reduce the risk of liver injury. Avoid exposure to bright sunlight or tanning beds while taking this medication, as it can cause itching, redness, and severe sunburn. If you are using Terbisil cream, avoid contact with the eyes. In case of accidental contact with the eyes, rinse them thoroughly with running water. Keep this cream out of reach of children. In the event of an allergic reaction, remove the cream and interrupt the treatment immediately.
Conclusion
Terbisil is a reliable antifungal medication that effectively treats various fungal infections of the skin, hair, and nails. By inhibiting squalene monooxygenase, it prevents the synthesis of ergosterol, an essential component of the fungal cell wall. This leads to weakening and death of the fungal cell, providing relief from infections.
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Manal –
Price pls
Medical Guidance Center –
Hello Manal, this is WikiKenko,
Terbisil Tablet 250 mg is an antifungal medication that fights infections caused by fungus. It is used to treat infections of the skin, hair, and nails caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. It is also effective against yeast infections of the skin, principally those caused by the genus Candida. To view the latest prices, kindly login.
Terbisil Tablet 250 mg is a prescription-only medication. It is important to consult with a doctor before taking this medication as it may have side effects and interactions with other medications. Some people taking Terbisil have developed severe liver damage leading to liver transplant or death. It is important to call your doctor at once if you have symptoms of liver damage such as nausea, upper stomach pain, vomiting, loss of appetite, tiredness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Some common side effects of Terbisil Tablet 250 Mg include abdominal discomfort, anorexia, nausea, diarrhea, headache, rash, and urticaria occasionally with arthralgia or myalgia. Less frequently taste disturbance1. These side effects are usually mild and subside with time. However, if any of these side effects do not resolve with time or worsen, it is important to consult your doctor.