Aminosteril N-Hepa

(1 customer review)

Aminosteril N-Hepa 8% is a vital solution utilized in parenteral nutrition, particularly beneficial for patients grappling with severe hepatic insufficiency. This article delves into the intricate details of this medication, encompassing its qualitative and quantitative composition, clinical indications, dosage regimen, contraindications, special warnings, and precautions.

Dosage form

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Generic Name (Ingredient)


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Qualitative and Quantitative Composition

Each 1000 ml of Aminosteril N-Hepa 8% solution for infusion comprises a balanced blend of essential amino acids, including L-isoleucine, L-leucine, L-lysine monoacetate, L-methionine, N-acetyl-L-cysteine, and others.

Ingredient Quantity
L-isoleucine 10.40 g
L-leucine 13.09 g
L-lysine monoacetate 9.71 g
L-methionine 1.10 g
N-acetyl-L-cysteine 0.70 g
Other essential amino acids As per formulation

Clinical Indications

Aminosteril N-Hepa 8% serves multiple purposes:

  • Supplying essential amino acids as an integral component of parenteral nutrition in severe hepatic insufficiency.
  • Facilitating nutrition delivery when oral or enteral routes are infeasible or insufficient.
  • Augmenting therapy with energy supplements, electrolytes, vitamins, and trace elements.

Dosage and Administration

The recommended dosage of Aminosteril N-Hepa 8% is tailored to individual patient needs:

  • Administer at a rate of 1.0 to 1.25 ml/kg body weight/hour, not exceeding 1.25 ml/kg body weight/hour.
  • Maximum daily dose: 1.5 g amino acids/kg body weight.
  • Infusion should be via a peripheral or central vein, ideally combined with energy supplements for optimal efficacy.


Avoid Aminosteril N-Hepa 8% administration in cases of:

  • Disturbance of amino acid metabolism.
  • Metabolic acidosis.
  • Fluid overload.
  • Hyponatremia or hypokalemia.
  • Renal or decompensated cardiac insufficiency.
  • Shock or hypoxia.

Special Warnings and Precautions

Vigilant monitoring of electrolytes, fluid balance, and acid-base equilibrium is imperative. Electrolytes and carbohydrates should be judiciously administered, while concurrent infusion with carbohydrate solutions and/or fat emulsions is recommended. The duration of Aminosteril N-Hepa use should align with clinical necessity and metabolic normalization.

How Aminosteril N-Hepa Works

Amino acids play a pivotal role in numerous physiological processes, contributing to ATP generation through their catabolism in muscle tissue.

Common Side Effects

  • Folic acid deficiency.
  • Chills.
  • Fever.
  • Flushing.
  • Increased sweating.
  • Metabolic disorder.
  • Vomiting.
  • Liver damage.


Aminosteril N-Hepa 8% emerges as a cornerstone in the management of severe hepatic insufficiency, offering a balanced formulation of essential amino acids crucial for optimal patient nutrition. However, cautious adherence to dosage guidelines and careful consideration of contraindications and precautions are paramount. Always seek guidance from a healthcare professional to ensure safe and efficacious use of this medication.

1 review for Aminosteril N-Hepa

  1. Shadrack komen

    How many of this 500mls should a patient administered with

    • WikiKenko - Health Encyclopedia

      Medical Guidance Center

      Hello Shadrack, this is Wikikenko,

      Thank you for your question regarding the recommended dosage of Aminosteril N-Hepa 8%. The amount administered depends on several factors, but as a general guideline:

      Infusion rate should be between 1.0-1.25 ml/kg of the patient’s body weight per hour.

      For a 70kg adult, the maximum daily dose would be approximately 1300ml (calculated as 1.5g amino acids/kg body weight x 70kg).

      Administration should be via a peripheral or central intravenous line.

      It’s always best to consult the prescribing physician to determine the specific dosage tailored to the individual patient’s needs, weight, and clinical condition. Other factors like concurrent medications and any liver/kidney function must also be considered.

      I hope this provides a starting point for understanding Aminosteril N-Hepa 8% dosage. Please don’t hesitate to ask if you need any part of the explanation clarified further. Proper administration is important to achieve the therapeutic benefits while avoiding potential side effects.

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