Description
Qualitative and Quantitative Composition
Each 1000 ml of Aminosteril N-Hepa 8% solution for infusion comprises a balanced blend of essential amino acids, including L-isoleucine, L-leucine, L-lysine monoacetate, L-methionine, N-acetyl-L-cysteine, and others.
| Ingredient | Quantity |
|---|---|
| L-isoleucine | 10.40 g |
| L-leucine | 13.09 g |
| L-lysine monoacetate | 9.71 g |
| L-methionine | 1.10 g |
| N-acetyl-L-cysteine | 0.70 g |
| Other essential amino acids | As per formulation |
Clinical Indications
Aminosteril N-Hepa 8% serves multiple purposes:
- Supplying essential amino acids as an integral component of parenteral nutrition in severe hepatic insufficiency.
- Facilitating nutrition delivery when oral or enteral routes are infeasible or insufficient.
- Augmenting therapy with energy supplements, electrolytes, vitamins, and trace elements.
Dosage and Administration
The recommended dosage of Aminosteril N-Hepa 8% is tailored to individual patient needs:
- Administer at a rate of 1.0 to 1.25 ml/kg body weight/hour, not exceeding 1.25 ml/kg body weight/hour.
- Maximum daily dose: 1.5 g amino acids/kg body weight.
- Infusion should be via a peripheral or central vein, ideally combined with energy supplements for optimal efficacy.
Contraindications
Avoid Aminosteril N-Hepa 8% administration in cases of:
- Disturbance of amino acid metabolism.
- Metabolic acidosis.
- Fluid overload.
- Hyponatremia or hypokalemia.
- Renal or decompensated cardiac insufficiency.
- Shock or hypoxia.
Special Warnings and Precautions
Vigilant monitoring of electrolytes, fluid balance, and acid-base equilibrium is imperative. Electrolytes and carbohydrates should be judiciously administered, while concurrent infusion with carbohydrate solutions and/or fat emulsions is recommended. The duration of Aminosteril N-Hepa use should align with clinical necessity and metabolic normalization.
How Aminosteril N-Hepa Works
Amino acids play a pivotal role in numerous physiological processes, contributing to ATP generation through their catabolism in muscle tissue.
Common Side Effects
- Folic acid deficiency.
- Chills.
- Fever.
- Flushing.
- Increased sweating.
- Metabolic disorder.
- Vomiting.
- Liver damage.
Conclusion
Aminosteril N-Hepa 8% emerges as a cornerstone in the management of severe hepatic insufficiency, offering a balanced formulation of essential amino acids crucial for optimal patient nutrition. However, cautious adherence to dosage guidelines and careful consideration of contraindications and precautions are paramount. Always seek guidance from a healthcare professional to ensure safe and efficacious use of this medication.
Shadrack komen –
How many of this 500mls should a patient administered with
Medical Guidance Center –
Hello Shadrack, this is Wikikenko,
Thank you for your question regarding the recommended dosage of Aminosteril N-Hepa 8%. The amount administered depends on several factors, but as a general guideline:
Infusion rate should be between 1.0-1.25 ml/kg of the patient’s body weight per hour.
For a 70kg adult, the maximum daily dose would be approximately 1300ml (calculated as 1.5g amino acids/kg body weight x 70kg).
Administration should be via a peripheral or central intravenous line.
It’s always best to consult the prescribing physician to determine the specific dosage tailored to the individual patient’s needs, weight, and clinical condition. Other factors like concurrent medications and any liver/kidney function must also be considered.
I hope this provides a starting point for understanding Aminosteril N-Hepa 8% dosage. Please don’t hesitate to ask if you need any part of the explanation clarified further. Proper administration is important to achieve the therapeutic benefits while avoiding potential side effects.