Description
Indications and Usage
Fluro-5 Deva I.V./I.A. Injection Solution Iceren Vial is indicated for the treatment of patients diagnosed with the following types of cancer:
- Adenocarcinoma of the Colon and Rectum
- Adenocarcinoma of the Breast
- Gastric Adenocarcinoma
- Pancreatic Adenocarcinoma
Dosage and Administration
Fluro-5 Deva can be administered intravenously either as a bolus or as an infusion. Individualization of the dose is crucial, and specific dosing recommendations should be referred to in the full prescribing information.
Recommended Doses for Specific Cancers
| Cancer Type | Recommended Dose |
|---|---|
| Colon and Rectal Adenocarcinoma | Refer to full prescribing information |
| Breast Adenocarcinoma | As part of a chemotherapy regimen |
| Gastric Adenocarcinoma | As part of a chemotherapy regimen |
| Pancreatic Adenocarcinoma | As part of a chemotherapy regimen |
Dosage Forms and Strengths
Fluro-5 Deva I.V./I.A. Injection Solution Iceren Vial is available in the following strengths:
- 500 mg in a 10 mL vial (single dose)
- 1 g in a 20 mL vial (single dose)
Contraindications
None reported.
Warnings and Precautions
Serious Adverse Reactions from Dihydropyrimidine Dehydrogenase (DPD) Deficiency
Patients with certain DPYD gene variants are at increased risk for toxicity. Fluorouracil is not recommended for patients with complete absence of DPD activity.
Cardiotoxicity
Monitor for cardiac adverse effects.
Hyperammonemic Encephalopathy
Be vigilant for altered mental status, confusion, or ataxia.
Clinical Pharmacology and Nonclinical Toxicology
Mechanism of Action
Fluorouracil interferes with cancer cell growth.
Toxicology Studies
Refer to full prescribing information.
Side Effects of Fluro-5 Deva
Fluro-5 Deva, also known as fluorouracil, may cause various side effects, ranging from common to rare. It is essential to be aware of these potential reactions and seek medical attention if necessary.
Serious Side Effects
- More Common Side Effects: Diarrhea, heartburn, mouth and lip sores.
- Less Common Side Effects: Black, tarry stools, fever with cough or hoarseness, lower back or side pain with fever or chills.
Rare Side Effects
- Blood-related: Blood in urine or stools, unusual bleeding or bruising.
- Skin-related: Pinpoint red spots on the skin.
Other Side Effects
More Common Side Effects
- Loss of appetite
- Nausea and vomiting
- Skin rash and itching
Less Common Side Effects
- Dry or cracked skin
- Temporary hair loss
Benefits of Fluro-5 Deva
Fluro-5 Deva I.V./I.A. Injection Solution Iceren Vial, known generically as fluorouracil, offers several benefits in cancer treatment. Let’s explore its advantages:
Indications and Usage
- Effective treatment for various types of cancer, including colon, breast, gastric, and pancreatic adenocarcinoma.
Dosage and Administration
- Available in convenient single-dose vials with different strengths.
- Flexible administration methods to suit individual patient needs.
Warnings and Precautions
- Alerts healthcare providers to potential serious adverse reactions, allowing for proactive monitoring and management.
Alternatives to Fluro-5 Deva
While Fluro-5 Deva is a trusted medication for cancer treatment, alternatives may be considered based on individual patient needs. Some alternatives to explore include:
- Sachajuan
- Ouidad
- Cantu
Precautions and Safety Considerations
Children
Not recommended for use in pediatric patients due to lack of established safety and efficacy.
Elderly Patients
Caution is advised in elderly patients, with close monitoring for adverse effects.
Pregnant Women
Not recommended during pregnancy due to potential risks to the fetus.
Breastfeeding Women
Not recommended during breastfeeding due to potential harm to the nursing infant.
Conclusion
Fluro-5 Deva I.V./I.A. Injection Solution Iceren Vial, or fluorouracil, is a valuable tool in the treatment of various cancers. Understanding its indications, dosages, precautions, and potential side effects is essential for both healthcare providers and patients. Always consult with a healthcare professional for personalized advice and treatment options.
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Medical Guidance Center –
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