Sirdalud Tablet

Sirdalud Tablet, also known as Tizanidine, is a potent muscle relaxant widely used to alleviate rigidity, inflammation, and swelling in conditions affecting the musculoskeletal system. This medication works by blocking specific chemical messengers in the brain responsible for such symptoms, effectively relieving muscle stiffness or spasms, thereby improving overall muscle movement and function.

Dosage form

Pack size


2 Mg



Generic Name (Ingredient)

Each Tablet Contains 2.288 Mg Of Tizanidine Hydrochloride, Equivalent To 2 Mg Of Tizanidine.

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Composition and Dosage

Each Sirdalud tablet contains 2 mg of the active ingredient, Tizanidine Hydrochloride. The dosage is typically determined by a healthcare professional based on the patient’s specific condition and response to the medication. It is crucial to follow the prescribed dosage instructions carefully.

Mechanism of Action

Sirdalud’s active component, Tizanidine, is a centrally acting muscle relaxant that primarily targets the spinal cord, reducing excessive muscle tone. This medication reduces spasticity by causing presynaptic inhibition of motor neurons through its agonist actions at Alpha-2 adrenergic receptor sites. Consequently, it leads to a reduction in the release of excitatory amino acids like glutamate and aspartate, which are responsible for neuronal firing that causes muscle spasms.

Availability and Prescription Requirements

Sirdalud is a prescription medication, meaning it is not available over-the-counter and can only be obtained with a valid prescription from a licensed healthcare provider. It is essential to consult with a healthcare professional for proper diagnosis and treatment recommendations.

Uses and Indications

Sirdalud is primarily used in the symptomatic treatment of painful muscle spasms associated with musculoskeletal conditions. Additionally, it is employed as an adjunctive therapy in the management of spasticity related to multiple sclerosis or spinal cord disorders. Sirdalud may also be prescribed for other conditions such as acute low back pain, drug withdrawal headaches, insomnia, migraines, seizures, and withdrawal from addictive substances.

Administration and Dosing Guidelines

Sirdalud should be taken as advised by your healthcare provider. Here are some general guidelines:

Dosage: Sirdalud is typically taken up to three times a day, with 6 to 8 hours between doses. Do not exceed three doses within a 24-hour period.
With or Without Food: You can take Sirdalud with or without food, but it is essential to maintain consistency in your approach.
Swallow Whole: Swallow the tablets whole with a full glass of water.
– Consistent Timing: Take your doses at the same time every day for optimal effectiveness.

Remember, these are general guidelines, and the exact dosage and timing may vary depending on your specific condition and response to the medication. Always follow your healthcare provider’s instructions carefully.

Precautions and Interactions

While taking Sirdalud, it is essential to consider the following precautions and potential interactions:

Alcohol: Avoid consuming alcohol while taking Sirdalud, as it may cause excessive drowsiness.
Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to conceive, or breastfeeding.
Liver Function: Sirdalud can potentially damage your liver, necessitating frequent blood tests to monitor liver function.
Drowsiness and Dizziness: Sirdalud may cause drowsiness and dizziness, so exercise caution while driving, operating machinery, or engaging in activities that require alertness.
Medication Interactions: Inform your healthcare provider about any other medications you are currently taking, as Sirdalud may interact with them.
Sudden Withdrawal: Do not stop taking Sirdalud abruptly without consulting your healthcare provider.

Sirdalud can interact with various medications, including antihypertensives, central nervous system (CNS) depressants, β-blockers, digoxin, and acetaminophen. These interactions can affect the efficacy of Sirdalud or the other medications, or increase the risk of side effects.

Sirdalud Tablet Onset of Action

The onset of action for Sirdalud (Tizanidine) varies depending on whether it is taken in a fasting state or with food:

  • Fasting State: The peak effect of a single dose (8 mg) is typically seen within 1 to 2 hours. The time to peak for both the capsule and tablet forms is about 1 hour.
  • Fed State: The time to peak is 3 to 4 hours for the capsule form and 1.5 hours for the tablet form.

Please note that these are general guidelines, and individual experiences may vary. Always consult with your healthcare provider for personalized advice.

Sirdalud Tablet
Sirdalud Tablet

Sirdalud Tablet Storage

To ensure the optimal effectiveness and safety of Sirdalud tablets, follow these storage guidelines:

  • Store the tablets in a cool and dry place, protected from light and moisture.
  • Keep the tablets below 30°C (86°F).
  • Store the medication in its original packaging.
  • Keep the tablets out of reach of children and pets.
  • Do not use the tablets beyond the expiry date mentioned on the packaging.
  • Discard any damaged tablets.
  • Dispose of unused or expired medication properly, following local regulations.

Side Effects

Like most medications, Sirdalud may cause some side effects, although not everyone experiences them, and their severity may vary. Common side effects associated with Sirdalud include:

  • Drowsiness
  • Fatigue
  • Dizziness
  • Dry mouth
  • Nausea
  • Gastrointestinal disturbances
  • Hypotension (low blood pressure)

In rare cases, Sirdalud may also cause bradycardia (slow heart rate), insomnia, hallucinations, altered liver enzymes, and acute hepatitis.

If you experience any unusual symptoms while taking Sirdalud, seek medical attention immediately.

Driving and Operating Machinery

Sirdalud can cause side effects such as drowsiness, fatigue, and dizziness, which can impair your ability to drive or operate heavy machinery. Therefore, it is generally recommended not to engage in these activities until you understand how Sirdalud affects you. If you feel drowsy, dizzy, or have trouble concentrating after taking Sirdalud, avoid driving or operating heavy machinery. Always consult with your healthcare provider for personalized advice.

Table: Key Information about Sirdalud Tablet

Aspect Details
Side Effects Drowsiness, fatigue, dizziness, dry mouth, nausea, gastrointestinal disturbances, hypotension
Dosage Up to 3 times a day, with 6-8 hours between doses; do not exceed 3 doses in 24 hours
Benefits Relieves muscle spasms, improves muscle movement, manages spasticity
Usage Musculoskeletal conditions, multiple sclerosis, spinal cord disorders, acute low back pain, drug withdrawal headaches, insomnia, migraines, seizures, withdrawal from addictive substances
Interactions Antihypertensives, CNS depressants, alcohol, β-blockers, digoxin, acetaminophen

Disclaimer: This information is provided for educational purposes only and is not intended to replace the advice of a medical professional. Always consult with a healthcare provider for proper diagnosis and treatment.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


The truth is that when we’re sick, or worried about getting sick, the internet won’t help.

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