Description
Composition
Each Clopixol Film Tablet comprises:
- Active Ingredient: 25 mg zuclopenthixol (as dihydrochloride)
- Excipients: Lactose monohydrate, hydrogenated castor oil, microcrystalline cellulose, among other inactive ingredients.
Indications
Clopixol is prescribed for:
- Schizophrenia: Effective in both acute and chronic cases, particularly for symptoms like hallucinations, delusions, and thought disorders.
- Other Psychoses: Used to manage conditions marked by agitation, restlessness, hostility, and aggression.
- Manic Episodes: Administered to patients with bipolar disorder during manic phases.
- Behavioral Disorders: Effective for mentally retarded patients exhibiting agitation and aggressive behavior.
Dosage and Administration
Adults:
- Initial Dose: Typically, 20-30 mg per day, adjustable as required.
- Maintenance Dose: Usually, 20-50 mg per day.
- Maximum Dose: 40 mg per single dose and up to 150 mg per day.
Special Populations:
- Elderly: Initial doses may need to be reduced to one-quarter or one-half of the standard starting dose.
- Renal Impairment: Normal doses can be administered, but halved in cases of renal failure.
- Hepatic Impairment: Use cautiously and monitor serum levels.
Contraindications
Clopixol should not be used in patients with:
- Hypersensitivity to zuclopenthixol or any excipients in the formulation.
- Severe circulatory collapse, coma, or significant depression of consciousness.
Warnings and Precautions
- Heart Conditions: Exercise caution in patients with heart conditions, including arrhythmias.
- Respiratory Issues: Monitor patients with severe respiratory problems.
- Liver and Kidney Problems: Dosage adjustments may be necessary.
- Epilepsy: Caution is advised for patients with a history of seizures.
- Parkinson’s Disease: Use cautiously in patients with Parkinson’s disease.
- Glaucoma: Monitor patients with raised intraocular pressure.
Side Effects
Common side effects include:
- Drowsiness: Sedation or reduced alertness.
- Dry Mouth: Decreased saliva production.
- Weight Gain: Increased body weight.
- Extrapyramidal Symptoms: Such as tremors, rigidity, and bradykinesia.
Storage
Store Clopixol in a cool, dry place away from direct sunlight and out of reach of children.
Interactions with Other Medications
Clopixol Film Tablet 25 mg can interact with several other medications, including:
- Tricyclic Antidepressants: Can enhance the sedative effects of Clopixol.
- Guanethidine and Similar Medicines: Reduced effectiveness when combined with Clopixol.
- Barbiturates and Similar Medicines: Increased sedative effects.
- Levodopa and Similar Medicines: Reduced effectiveness when taken with Clopixol.
- Metoclopramide: Increases the risk of extrapyramidal symptoms.
- Alcohol: Enhances the sedative effects of Clopixol.
Inform your healthcare provider about all medications you are currently taking to avoid potential interactions.
Contraindications for Clopixol
Clopixol should not be used in patients with:
- Hypersensitivity: Allergy to zuclopenthixol or any of its excipients.
- Severe Circulatory Collapse: Conditions like shock or severe hypotension.
- Coma: Unconscious patients.
- Severe Depression of Consciousness: Such as in cases of alcohol or barbiturate intoxication.
Always consult with a healthcare professional before starting Clopixol to ensure it is safe for you.
Onset of Action
The onset of action for Clopixol Film Tablet 25 mg varies, generally taking about 20 hours (ranging from 12-28 hours) to start showing effects. However, noticeable improvement in symptoms can depend on the individual and the condition being treated.
Driving and Operating Machinery
Exercise caution when driving or operating heavy machinery while taking Clopixol, as it can cause sedation and affect mental alertness and physical coordination.
Alcohol Consumption
Avoid alcohol while taking Clopixol, as it can increase the sedative effects of the medication.
Precautions for Clopixol Film Tablet 25 mg
When taking Clopixol Film Tablet 25 mg, be aware of the following precautions to ensure safe and effective use:
Medical Conditions:
- Liver Disease: Use cautiously in patients with liver problems.
- Cardiac Disease: Caution for patients with heart conditions, including arrhythmias.
- Respiratory Disease: Monitor patients with severe respiratory conditions.
- Renal Failure: Dose adjustments may be necessary.
- Epilepsy: Use with caution if you have a history of seizures.
- Parkinson’s Disease: Use cautiously in patients with Parkinson’s disease.
- Narrow Angle Glaucoma: Monitor patients with raised intraocular pressure.
- Prostatic Hypertrophy: Caution for patients with an enlarged prostate.
- Thyroid Disorders: Monitor patients with hypothyroidism or hyperthyroidism.
- Myasthenia Gravis: Use cautiously in patients with this condition.
- Phaeochromocytoma: Exercise caution in patients with this rare cancer.
Other Considerations:
- Alcohol: Avoid alcohol as it enhances the sedative effects of Clopixol.
- Driving and Operating Machinery: Be cautious as Clopixol can cause drowsiness.
- Blood Clots: Inform your doctor if you have a history of blood clots.
- Stroke Risk Factors: Monitor patients with risk factors for stroke, such as smoking or hypertension.
- Electrolyte Imbalance: Ensure adequate potassium and magnesium levels in your blood.
Always consult with your healthcare provider before starting or adjusting the medication to ensure it is safe for you.
Benefits of Clopixol Film Tablet 25 mg
Clopixol Film Tablet 25 mg offers several benefits for individuals with specific mental health conditions, including:
- Treatment of Schizophrenia: Effective for both acute and chronic schizophrenia, managing symptoms like hallucinations, delusions, and thought disorders by correcting chemical imbalances in the brain.
- Management of Other Psychoses: Used to treat other psychoses characterized by disturbances in thinking, emotional reactions, and behavior.
- Control of Manic Episodes: Beneficial for patients experiencing manic episodes associated with bipolar disorder, helping to stabilize mood and reduce symptoms of mania.
- Behavioral Disorders: Effective for managing agitation and aggressive behavior in mentally retarded patients.
- Long-Lasting Effects: Has a relatively long half-life, providing sustained relief from symptoms.
- Correcting Chemical Imbalances: By acting on nerve pathways in specific brain areas, Clopixol helps to correct chemical imbalances that cause mental illnesses.
Clopixol Film Tablet 25 mg: Key Information Table
| Category | Information |
|---|---|
| Active Ingredient | 25 mg zuclopenthixol (as dihydrochloride) |
| Indications | Schizophrenia, Other psychoses, Manic episodes, Behavioral disorders |
| Dosage | Initial: 20-30 mg/day; Maintenance: 20-50 mg/day; Maximum: 40 mg/single dose, 150 mg/day |
| Common Side Effects | Drowsiness, Dry mouth, Weight gain, Extrapyramidal symptoms |
| Contraindications | Hypersensitivity, Severe circulatory collapse, Coma, Severe depression of consciousness |
| Warnings/Precautions | Heart conditions, Respiratory issues, Liver/kidney problems, Epilepsy, Parkinson’s disease |
| Interactions | Tricyclic antidepressants, Guanethidine, Barbiturates, Levodopa, Metoclopramide, Alcohol |
| Storage | Cool, dry place away from sunlight, Keep out of reach of children |
| Benefits | Effective for schizophrenia and psychoses, Manages manic episodes, Long-lasting effects |
Always consult your healthcare provider for personalized advice and before making any changes to your medication regimen. If you have further questions or need more information, do not hesitate to ask.
Jeanette –
I would like to inquire the availability of
CLOPIXOL 25MG tablets
And if you do ship to the Philippines? This is for my brother who is the patient. Thanks
Medical Guidance Center –
Hello Jeanette, this is WikiKenko.
Clopixol Film Tablet 25 Mg is a prescription-only medicine. The active ingredient in Clopixol is zuclopenthixol dihydrochloride. It belongs to a group of medicines known as antipsychotics (also called neuroleptics).
There are many potential side effects associated with taking Clopixol. Some of these include blood and lymphatic system disorders, immune system disorders, endocrine disorders, metabolism and nutrition disorders, psychiatric disorders, nervous system disorders, eye disorders, ear and labyrinth disorders, cardiac disorders, vascular disorders, respiratory, thoracic and mediastinal disorders, gastrointestinal disorders, hepato-biliary disorders, skin and subcutaneous tissue disorders, musculoskeletal and connective tissue disorder, renal and urinary disorders, reproductive system and breast disorders.
I’m sorry, but we couldn’t find any specific information about where to find Clopixol Film Tablet 25 Mg in the Philippines. It’s important to consult with a healthcare professional before taking this medication. They can provide you with more detailed information about its uses and potential side effects.