Unisom Tablet

(1 customer review)

Unisom stands as a prominent medication designed primarily to facilitate sleep. In this comprehensive discourse, we delve into the composition, uses, mechanism of action, dosage, side effects, precautions, and interactions of these tablets, offering insights into its therapeutic potential and clinical implications.

Dosage form

Pack size


25 Mg



Generic Name (Ingredient)

Each Unisom Tablet Contains 25 Mg Of Doxamine Succinate And Fd & C Blue No: 1 As Dyestuff.

Assuming your emergency circumstances for this product, visit Urgent Quotation page. Besides, for any pharmaceutical questions, please ask us in the comments section.


Unisom Tablet Composition

Unisom tablets embody a formulation comprising 25.5 mg of doxylamine succinate, which is equivalent to 25 mg of doxylamine, along with microcrystalline cellulose, dibasic calcium phosphate dihydrate, sodium starch glycolate, FD&C Blue No.1 12% aluminum lake (E133), and magnesium stearate.


Unisom tablets serve as a remedy for insomnia and sleep onset difficulties. Furthermore, they demonstrate efficacy in alleviating symptoms associated with allergies, including sneezing, itching, watery eyes, and runny nose.

How It Works

Unisom, characterized as an antihistamine, acts by mitigating the effects of histamine, a natural chemical in the body, thereby alleviating symptoms such as sneezing, itching, and nasal discharge. Additionally, its antihistaminic properties induce drowsiness, rendering it effective as a sleep aid.


Unisom tablets are administered orally with water approximately 30 minutes before bedtime. The medication is typically used for short durations until symptoms subside.

Side Effects

While generally well-tolerated, Unisom may elicit common side effects such as blurred vision, dry mouth, constipation, mild dizziness, and headaches. Additionally, serious adverse effects including confusion, hallucinations, severe drowsiness, and urinary issues necessitate prompt medical attention.


Individuals allergic to Unisom should refrain from its use. Moreover, caution is warranted in patients with conditions such as glaucoma, prostatic hypertrophy, urinary retention, and respiratory disorders. Pregnant and breastfeeding women should seek medical advice prior to initiating its therapy.

Pregnancy and Breastfeeding

Unisom, containing doxylamine succinate, is deemed safe for short-term use during pregnancy and is often employed to alleviate insomnia and morning sickness. However, consultation with a healthcare provider is prudent prior to its utilization during pregnancy or lactation.

How long does it take to work?

Unisom typically manifests its therapeutic effects within 2 to 4 hours post-administration. The medication is ingested 30 minutes before bedtime to facilitate sleep onset.

Maximum dosage?

The maximum dosage of this tablet varies based on the formulation. For tablets, the recommended dosage is one 25 mg tablet at bedtime, not exceeding 2 weeks of consecutive use.


Unisom tablets offer multifaceted benefits, including sleep aid, allergy relief, morning sickness management, and non-habit forming properties, promoting its safe and efficacious use.


This tablet may interact with alcohol, hypnotics, anxiolytics, narcotic analgesics, neuroleptic drugs, and tricyclic antidepressants, necessitating caution and healthcare provider consultation.

Mechanism of Action

Unisom exerts its therapeutic effects through antihistaminic action, sedation induction, and anticholinergic properties, culminating in symptomatic relief and sleep promotion.

How long does it take to leave your system?

Unisom possesses an elimination half-life of approximately 10 to 12 hours, with complete systemic elimination occurring over an average duration of 2.29 days in healthy adults.


Unisom tablets emerge as a valuable therapeutic option for individuals grappling with sleep disturbances and allergy-related symptoms. With its well-established safety profile and multifaceted benefits, this tablet stands as a cornerstone in the management of sleep disorders and allergic manifestations. However, prudent adherence to dosage guidelines, vigilance for adverse effects, and healthcare provider consultation are imperative to ensure optimal therapeutic outcomes and patient safety.

Topic Details
Composition 25.5 mg of doxylamine succinate, microcrystalline cellulose, dibasic calcium phosphate dihydrate, sodium starch glycolate, FD&C Blue No.1 12% aluminum lake (E133), magnesium stearate
Uses Insomnia treatment, relief from allergy symptoms
Dosage Orally with water, 30 minutes before bedtime, short-term use
Side Effects Blurred vision, dry mouth, constipation, dizziness, headaches, confusion, hallucinations, severe drowsiness, urinary issues
Precautions Allergy to Unisom, caution in glaucoma, prostatic hypertrophy, urinary retention, respiratory disorders, pregnancy, breastfeeding
Interactions Alcohol, hypnotics, anxiolytics, narcotic analgesics, neuroleptic drugs, tricyclic antidepressants
Mechanism of Action Antihistaminic, sedative, anticholinergic
Duration in the System 10 to 12 hours (half-life), complete elimination in 2.29 days

1 review for Unisom Tablet

  1. Zia cheema


    • WikiKenko - Health Encyclopedia

      Medical Guidance Center

      Hello Leyla, this is Wikikenko,
      Thank you for taking the time to provide feedback on our Unisom Tablet page. Comments like yours help us ensure we are meeting our goal of providing clear and accurate information to support informed healthcare decisions. We appreciate positive comments, as it helps us recognize what aspects of our content are effective. Please feel free to contact us if you have any other questions or suggestions on how we can continue to improve. Your feedback plays an important role in helping other users.

Add a review

Your email address will not be published. Required fields are marked *

Use the form below to report an error

Please answer the questions as thoroughly and accurately as possible. Your answers will help us better understand what kind of mistakes happen, why and where they happen, and in the end the purpose is to build a better archive to guide researchers and professionals around the world.

In case there is no image available for this drug on the Wikikenko health encyclopedia, you can also upload images/leaflets of this product. After our pharmaceutical specialist's confirmation, your images/leaflet will be added to our archive with the gratitude of your name. for sure your cooperation would help researchers to find their answers. Upload Images/Leaflet (Less than 2MB)

The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


The truth is that when we’re sick, or worried about getting sick, the internet won’t help.

According to Wikipedia, cyberchondria is a mental disorder consisting in the desire to independently make a diagnosis based on the symptoms of diseases described on Internet sites.

Why you can't look for symptoms on the Internet

If diagnoses could be made simply from a textbook or an article on a website, we would all be doctors and treat ourselves. Nothing can replace the experience and knowledge of specially trained people. As in any field, in medicine there are unscrupulous specialists, differences of opinion, inaccurate diagnoses and incorrect test results.