Description
Tricef Oral Suspension Composition
Active Ingredient
- Cefdinir: Each 5 ml of the prepared suspension contains 125 mg of cefdinir.
Inactive Ingredients
- Sucrose
- Xanthan gum
- Guar gum
- Citric acid anhydrous
- Trisodium citrate
- Aerosil 200
- Magnesium stearate
- Sodium benzoate (E211)
- Strawberry flavoring
Indications
Tricef is prescribed for various bacterial infections, including:
In Adults and Adolescents
- Community-acquired pneumonia (CAP)
- Acute exacerbations of chronic bronchitis (AECB)
- Acute bacterial sinusitis
- Tonsillitis and pharyngitis
- Uncomplicated skin and soft tissue infections
In Children
- Acute otitis media (middle ear infection)
- Tonsillitis and pharyngitis
- Uncomplicated skin and soft tissue infections
Dosage and Administration
Preparation of Suspension
- Shake the bottle to loosen the powder.
- Add water up to the mark indicated on the bottle.
- Shake well until the powder is completely dissolved.
Dosage
- Adults and Adolescents: The dosage varies depending on the type and severity of the infection.
- Children (over 6 months): The recommended dose is 8 mg/kg daily, either as a single dose or divided into two doses.
Mechanism of Action
Cefdinir operates by inhibiting the synthesis of the bacterial cell wall, resulting in bacterial cell death. It is effective against a wide range of Gram-positive and Gram-negative bacteria, including those producing beta-lactamase enzymes.
Food Interaction
Tricef Oral Suspension can be taken with or without food. Maintaining a fixed time each day for dosage enhances its efficacy. If you have specific dietary concerns or experience any side effects, consult your healthcare provider.
Duration of Treatment
The typical duration of treatment with Tricef is 7 days, which may extend up to 14 days based on the infection’s severity. Adhering to the prescribed duration is essential to fully eradicate the infection and prevent antibiotic resistance.
Precautions
Allergies
- Hypersensitivity: Avoid using Tricef if allergic to cefdinir, other cephalosporins, or any of its components.
Medical Conditions
- Gastrointestinal Diseases: Use cautiously if you have a history of gastrointestinal diseases, particularly colitis.
- Renal Impairment: Dosage adjustments may be necessary for patients with severe renal impairment (creatinine clearance < 20 ml/min).
Pregnancy and Lactation
- Pregnancy: Use with caution. Consult your healthcare provider.
- Breastfeeding: It is unclear if cefdinir passes into breast milk. Consult your healthcare provider.
Drug Interactions
- Anticoagulants: Tricef may increase prothrombin time, raising bleeding risk when taken with anticoagulants like warfarin.
General Precautions
- Complete the full course of the antibiotic as prescribed, even if you feel better, to prevent the development of antibiotic-resistant bacteria.
Alcohol Consumption
It is advisable to avoid alcohol while taking Tricef as it can exacerbate side effects such as dizziness and nausea and may impair your body’s ability to fight infections.
Tricef Oral Suspension Storage
Storage of Dry Powder
- Store the dry powder at room temperature, below 25°C.
Storage of Reconstituted Suspension
- Refrigerate the suspension after reconstitution.
- Use within 14 days and discard any unused portion after this period.
- Keep the bottle tightly closed.
Missed Dose
If you miss a dose of Tricef Oral Suspension:
- Take it as soon as you remember unless it is close to the time for your next dose.
- Skip the missed dose if it is almost time for your next dose and continue your regular dosing schedule.
- Do not double the dose to make up for the missed one.
Common Side Effects
Typical side effects of Tricef include:
- Diarrhea
- Stomach pain
- Gas
- Heartburn
- Nausea
- Vomiting
These side effects are usually mild and transient. However, consult your healthcare provider if you experience severe or persistent symptoms.
Table: Tricef Oral Suspension Information
| Category | Details |
|---|---|
| Side Effects | Diarrhea, Stomach pain, Gas, Heartburn, Nausea, Vomiting |
| Dosage | Adults: Varies; Children: 8 mg/kg daily (single or divided doses) |
| Benefits | Broad-spectrum antibiotic, Effective against beta-lactamase producing bacteria, Versatile usage for multiple infections, Well-tolerated with manageable side effects |
| Usage | Treats CAP, AECB, Sinusitis, Tonsillitis, Pharyngitis, Otitis media, Skin infections |
| Precautions | Allergies, Gastrointestinal diseases, Renal impairment, Pregnancy, Breastfeeding, Drug interactions with anticoagulants |
| Storage | Dry powder: Room temperature; Reconstituted suspension: Refrigerate, use within 14 days |
| Food Interaction | Can be taken with or without food |
| Missed Dose | Take as soon as remembered unless close to next dose; Do not double doses |
By understanding the proper usage, precautions, and storage of Tricef Oral Suspension, patients can effectively manage bacterial infections while minimizing risks and side effects. Always consult a healthcare provider for personalized medical advice.

















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