Tribudat Forte Tablet

Tribudat Forte is a medication that can provide relief to individuals suffering from irritable bowel syndrome and postoperative paralytic ileus. Its active ingredient Trimebutine maleate possesses marked anti-serotonin activity and moderate opiate receptor affinity, making it effective in regulating the movement of the intestinal tract. With proper dosage and usage, Tribudat Forte can help accelerate…

Generic Name (Ingredient)

Bovine Lactose Monohydrate 180 Mg

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Tribudat Forte is primarily used to treat symptoms associated with irritable bowel syndrome (spastic colon) and postoperative paralytic ileus. It can also help accelerate the resumption of the intestinal transit following abdominal surgery. Trimebutine maleate, the active ingredient in Tribudat Forte, is a noncompetitive spasmolytic agent with moderate opiate receptor affinity and marked anti-serotonin activity, especially on ‘mu’ receptors.


For adults, the recommended dosage of Tribudat Forte is 1-2 tablets three times a day. It’s important to follow your doctor’s instructions regarding dosage and usage to ensure the best possible results.

Side Effects

Like any medication, Tribudat Forte may cause side effects. Some common side effects include dry mouth, heartburn, nausea, diarrhea, constipation, drowsiness, dizziness, tiredness, or headache. If you experience any of these side effects, contact your doctor right away.

Mechanism of Action

As mentioned earlier, Trimebutine maleate is the active ingredient in Tribudat Forte. It possesses moderate opiate receptor affinity and has marked anti-serotonin activity, especially on ‘mu’ receptors. This medication induces regulation of spontaneous activity and increases synchronization between electrophysiological spikes and contractions in isolated guinea pig strips of colon and ileum. At high concentrations, Trimebutine is shown to inhibit the extracellular Ca2+ influx in the smooth muscle cells through voltage-dependent L-type Ca2+ channels and further Ca2+ release from intracellular Ca2+ stores.


If you suffer from irritable bowel syndrome or postoperative paralytic ileus, Tribudat Forte may be a helpful medication for you. With its active ingredient Trimebutine maleate, it can help regulate your intestinal tract and alleviate symptoms associated with these conditions. Remember to follow your doctor’s instructions regarding dosage and usage, and contact them if you experience any side effects.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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