Rifocin Im Injection Icin Solution Iceren Ampul 250 Mg/3Ml

Rifocin is a powerful antibiotic that belongs to the rifamycin group of medications. It is commonly used to treat a variety of infections caused by gram-positive microorganisms. The active ingredient in Rifocin is rifamycin SV (sodium salt), and it comes in different formulations such as ampoules and ear drops.

Manufacturer

Origin

Generic Name (Ingredient)

Rifamycin Sv 250 Mg Lidocaine Hydrochloride Monohydrate 10 Mg

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Description

Rifamycins are a class of antibiotics that are derived from the bacterium Amycolatopsis rifamycinica. They are known for their broad-spectrum activity against a wide range of gram-positive and some gram-negative bacteria. Rifocin, in particular, is effective against infections caused by microorganisms that are sensitive to the rifamycin compound.

Rifocin Im Injection Composition

Each 3 mL ampule of Rifocin contains the following active and inactive ingredients:

Active Ingredient:

  • Rifamisin SV: 250 mg

Inactive Ingredients:

  • Lidocain hidroklorür monohidrat: 10 mg
  • Ascorbic acid
  • Disodium EDTA
  • Polyvinylpyrrolidone K17
  • Water for injection
  • Sodium bicarbonate
  • Sodium hydroxide
  • Potassium metabisulfite

The combination of rifamycin SV and lidocaine hydrochloride monohydrate in Rifocin provides both the antibiotic and local anesthetic properties, making it suitable for intramuscular administration.

Indications

Rifocin is primarily prescribed for the following conditions:

1. Infections caused by gram-positive microorganisms that are sensitive to it, especially when other antibiotic treatments have failed. This includes a wide range of bacterial infections, such as those caused by Staphylococcus, Streptococcus, and Enterococcus species.

2. Skin and soft tissue infections, such as:

  • Furunculosis (boils)
  • Pyoderma (pus-filled skin infection)
  • Abscesses
  • Lymphadenitis (lymph node inflammation)

3. Osteomyelitis (bone inflammation)

4. Bronchopulmonary infections caused by gram-positive microorganisms, including staphylococcal bacteremia (proliferation of Staphylococcus bacteria in the blood).

5. Bacterial infections related to the bile ducts, including those caused by gram-negative microorganisms or mixed flora.

Rifocin is particularly useful in situations where other antibiotic treatments have been unsuccessful or when the infection is caused by microorganisms that are resistant to more commonly used antibiotics.

Precautions

It is essential to consider the following precautions when using Rifocin:

1. Allergy: Do not use it if you are allergic to rifamycin or any other ingredients in the medication, including lidocaine.

2. Liver Failure: Rifocin should be avoided in patients with severe liver failure, as it is primarily metabolized and eliminated through the liver.

3. Bile Duct Obstruction: It should not be used in individuals with a condition that causes obstruction of the bile ducts, as this can affect the drug’s metabolism and excretion.

4. Pregnancy: The use of Rifocin during pregnancy, especially in the first three months, should be carefully considered. The potential benefits and risks to the mother and the developing fetus must be weighed before initiating treatment.

It is crucial to inform your healthcare provider about your medical history and any other conditions you may have before starting Rifocin therapy.

Side Effects

As with any medication, Rifocin may cause a range of side effects. The most common side effects associated with it include:

1. Discoloration of body fluids:

– Red, orange, or brown discoloration of the skin, tears, sweat, saliva, urine, or stools

2. Gastrointestinal effects:

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach pain
  • Belching
  • Bloating
  • Loss of appetite

3. Neurological effects:

  • Headache

4. Dermatological effects:

  • Mild skin rash or itching

While these side effects are generally mild and manageable, it is essential to monitor for any serious adverse reactions. If you experience any of the following, you should contact your healthcare provider immediately:

  • Severe skin rash or itching
  • Pale skin
  • Weakness
  • Easy bruising or bleeding
  • Fever
  • Chills
  • Body aches
  • Flu-like symptoms
  • Eye pain or redness
  • Vision loss

Your healthcare provider can assess the severity of the side effects and determine the appropriate course of action, which may include adjusting the dosage, temporarily discontinuing the medication, or switching to an alternative treatment.

Administration

Rifocin IM Injection is intended for intramuscular administration and should be administered by a healthcare professional. The steps for administering Rifocin IM Injection are as follows:

1. Gather the necessary supplies: needles, syringes, alcohol swabs, gauze pad, the vial containing the drug solution, a sharps container, and band-aids.

2. Wash your hands thoroughly with soap and water.

3. Disinfect the rubber top of the vial using an alcohol swab, wiping in an outward circular motion for 10 seconds.

4. Remove the needle cover and draw the correct volume of the drug solution into the syringe. Be sure to remove any air bubbles that may be present.

5. Choose the injection site, which should be the middle outer part of the thigh. Clean the skin at the injection site with an alcohol swab.

6. Spread the skin at the injection site between your thumb and index finger.

7. Inject the medication into the muscle, ensuring not to exceed 3 mL at a single site. If the total volume is more than 3 mL, divide the drug solution into two equal volumes and inject at two different sites.

8. Apply a band-aid to the injection site, if necessary.

It is crucial to follow the healthcare provider’s instructions carefully and to not exceed the recommended dosage or injection volume to minimize the risk of complications.

Dosage

The dosage of Rifocin can vary depending on the specific condition being treated. Here are some common dosage guidelines:

1. Tuberculosis:

  • Adults: 10 mg/kg, in a single daily administration, not to exceed 600 mg/day, oral or IV
  • Pediatric Patients: 10–20 mg/kg, not to exceed 600 mg/day, oral or IV

2. Traveler’s Diarrhea:

  • Adults and Pediatric Patients (12 years or older): 200 mg orally 3 times a day for 3 days

3. Hepatic Encephalopathy:

  • Adults: 550 mg orally twice a day

4. Irritable Bowel Syndrome:

  • Adults: 550 mg orally 3 times a day for 14 days
  • If symptoms recur, patients can be retreated up to 2 times with the same dosage regimen

It is important to note that these are general guidelines, and the exact dosage may vary depending on the individual patient’s condition, response to treatment, and other factors. Always consult with a healthcare professional to determine the appropriate dosage for your specific situation.

Drug Interactions

Rifocin, like any other medication, can interact with other drugs, potentially affecting their effectiveness or increasing the risk of side effects. It is crucial to inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking, including prescription and over-the-counter medicines.

Some key points to consider regarding drug interactions with Rifocin:

1. Drug-Drug Interactions: Rifocin may interact with other medications, potentially affecting how they work or increasing the risk of side effects. For example, taking Rifocin with certain cough medicines or sleep aids could cause the two medications to affect each other.

2. Drug-Food/Drink Interactions: Certain foods or beverages can also interact with Rifocin, potentially altering its effectiveness or safety. For instance, consuming alcohol while taking Rifocin could be dangerous.

3. Drug-Condition Interactions: Underlying health conditions can also influence the way Rifocin interacts with the body. Patients with certain medical problems may need to avoid or use Rifocin with caution.

To minimize the risk of harmful interactions, it is crucial to disclose your complete medical history and current medication regimen to your healthcare provider. They can then assess the potential for drug interactions and make appropriate adjustments to your treatment plan.

Contraindications

Rifocin should not be used in the following situations:

1. Allergy: If you are allergic to rifamycin or any other ingredients in Rifocin, including lidocaine, you should not use this medication.

2. Severe Liver Failure: Rifocin is primarily metabolized and eliminated through the liver, so it should not be used in patients with severe liver failure.

3. Obstruction of Bile Ducts: Individuals with a condition that causes obstruction of the bile ducts should avoid using Rifocin, as this can affect the drug’s metabolism and excretion.

Additionally, the use of Rifocin during pregnancy and breastfeeding should be carefully considered. The potential benefits and risks to the mother and the developing fetus or breastfed infant must be weighed before initiating treatment.

It is essential to inform your healthcare provider about your medical history and any other conditions you may have to ensure the safe and appropriate use of Rifocin.

Storage and Handling

Proper storage and handling of Rifocin are crucial to maintain the medication’s effectiveness and safety. Here are some guidelines for storing Rifocin at home:

1. Choose the right location: Store Rifocin in a cool, dry place, away from heat and moisture. Avoid storing it in areas that are prone to high temperatures or humidity, such as the bathroom or kitchen.

2. Consider refrigeration: Refrigeration can help maintain the stability of Rifocin. If possible, store the medication in a small, dedicated refrigerator set to the appropriate temperature range.

3. Proper packaging: Seal Rifocin in an airtight container or bag, preferably with an oxygen absorber, to protect it from environmental factors that could degrade the medication.

4. Check expiration dates: While the “use by” date on the packaging is important, most medications, including Rifocin, can remain effective for some time after this date, as long as they have been stored properly.

5. Keep out of reach of children: Ensure that all medications, including Rifocin, are stored out of the reach of children to prevent accidental ingestion or poisoning.

By following these guidelines, you can help ensure that your Rifocin remains potent and safe for use as prescribed by your healthcare provider.

Duration of Treatment

The duration of Rifocin (Rifampin) treatment can vary depending on the specific condition being treated. Here are some general guidelines:

1. Tuberculosis:

  • Initial Phase: 2 months, involving Rifocin along with other drugs like isoniazid, pyrazinamide, and possibly streptomycin or ethambutol.
  • Continued Phase: At least 4 months, with Rifocin and isoniazid.

2. Traveler’s Diarrhea:

  • 3 days

3. Hepatic Encephalopathy:

  • No specific duration, but the dosage is 550 mg orally 2 times a day.

4. Irritable Bowel Syndrome:

  • 14 days
  • If symptoms recur, patients can be retreated up to 2 times with the same dosage regimen.

It is important to note that these are general guidelines, and the exact duration of Rifocin treatment may vary based on the individual patient’s condition, response to treatment, and other factors. Always follow the instructions provided by your healthcare provider and complete the full course of treatment to ensure the best possible outcome.

Conclusion

In conclusion, Rifocin is a versatile antibiotic that plays a crucial role in the management of various bacterial infections. By understanding its composition, indications, precautions, side effects, administration, dosage, drug interactions, contraindications, storage, and treatment duration, healthcare professionals and patients can work together to ensure the safe and effective use of this medication.

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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.

Cyberchondria

The truth is that when we’re sick, or worried about getting sick, the internet won’t help.

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If diagnoses could be made simply from a textbook or an article on a website, we would all be doctors and treat ourselves. Nothing can replace the experience and knowledge of specially trained people. As in any field, in medicine there are unscrupulous specialists, differences of opinion, inaccurate diagnoses and incorrect test results.

 

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