Neofleks 1/3 I.V. Infusion Icin Injection Solution

Description

The ingredients

The Neofleks 1/3 I.V. Infusion Icin Injection Solution comprises Dextrose Monohydrate and Sodium Chloride as its active ingredients. These constituents form the foundation of its therapeutic efficacy.

Active Ingredients	Quantity in 100 ml Solution
– Dextrose Monohydrate (C6H12O6)	3.33 grams
– Sodium Chloride (NaCl)	0.3 grams

Ionic Concentrations

Ions	Concentration (mEq/L)
– Sodium	51.3
– Chloride	51.3

The ionic composition of the solution ensures the balance of essential electrolytes within the patient’s system.

Dextrose Monohydrate

Dextrose Monohydrate, often recognized as glucose or corn sugar, serves as a fundamental binder in the pharmaceutical realm. Derived from corn, it is a type of sugar familiar in culinary applications. In medicine, dextrose is found in solutions designed to provide additional fluids and calories to patients, particularly when energy replenishment is necessary. Furthermore, dextrose can serve as a vehicle for delivering other injectable medications, a testament to its versatility. Notably, it exists in two stereo-isomers, with only one, D-glucose, exhibiting biological activity, often referred to as dextrose monohydrate.

Sodium Chloride

Sodium Chloride, more colloquially known as table salt, consists of sodium and chloride ions in a 1:1 ratio. Its presence significantly contributes to the salinity of seawater and the extracellular fluid in multicellular organisms. Beyond its culinary applications, sodium chloride is a pivotal substance in various industrial processes, providing sources for essential sodium and chlorine compounds used in chemical synthesis. In the medical realm, it is introduced via injections to create saline solutions, serving multiple purposes:

• IV Drips: Used to combat dehydration and electrolyte imbalances.
• Saline Flush Injections: Employed to clear catheters or IV lines following medication administration.
• Nasal Irrigation: Eases congestion and maintains nasal moisture.
• Wound Cleaning: Ensures a sterile environment for wound care.
• Eye Drops: Alleviates eye redness, dryness, and tearing.
• Inhalation: Facilitates mucus production for easier removal.

Pharmaceutical Form

Neofleks 1/3 I.V. Infusion Icin Injection Solution is a sterile, apyrogenic solution meticulously designed for intravenous infusion. This colorless, clear, and odorless solution boasts a particle-free purity, fostering aseptic conditions in medical settings.

Characteristics

• pH: The solution exhibits a pH range of 3.2-6.5, ensuring compatibility with the physiological environment.
• Osmolarity: Total osmolarity measures 287.5 mOsm/L, a critical parameter for fluid balance.
• Electrolyte Concentrations: With sodium and chloride concentrations at 51.3 mEq/L, it aligns with the body’s electrolyte needs.

Therapeutic Indications

Neofleks 1/3 I.V. Infusion Icin Injection Solution finds its application in situations involving chloride loss equal to or greater than sodium loss, such as sweating, vomiting, and gastric aspiration. It plays a crucial role in patients requiring fluid alongside blood transfusion. Moreover, in pre- and post-operative care, it serves as the initial hydration solution, effectively restoring renal function by compensating for extracellular fluid losses.

Dosage and Administration

The dosage and infusion rate are meticulously determined by healthcare professionals. These decisions hinge on factors like patient age, weight, clinical and biological condition, and concomitant treatments. As a general guideline, adults, adolescents, and the elderly may receive 500 to 3000 mL within 24 hours, while infants and children may require 20 to 100 mL per kilogram of body weight within the same timeframe.

Intravenous administration through sterile apyrogenic sets ensures the safe delivery of the solution. Close monitoring of urine output and serum sodium and electrolyte concentrations is imperative during the administration.

Special Populations

No specific dosage recommendations are provided for patients with renal or hepatic failure, as comprehensive studies targeting this population are currently unavailable. In pediatric cases, as in adults, dosages and infusion rates are meticulously curated by healthcare providers based on individual parameters and concomitant treatments.

Neofleks 1/3 I.V. Infusion Icin Injection Solution Benefits

This versatile solution offers substantial benefits in conditions where chloride loss equals or surpasses sodium loss, such as sweating, vomiting, and gastric aspiration. It comes to the aid of patients requiring both fluids and blood transfusions. In the realm of pre- and post-operative care, it assumes a pivotal role as the primary hydration solution, initiating renal function restoration by compensating for extracellular fluid deficits. As with any medical treatment, it is imperative to consult with a healthcare provider before embarking on a new regimen.

Conclusion

Neofleks 1/3 I.V. Infusion Icin Injection Solution stands as a beacon of hope in the intricate landscape of intravenous medical care. With its meticulous composition, versatility, and role in replenishing essential electrolytes, it serves as a lifeline for those in need. Whether it’s addressing chloride imbalances, facilitating blood transfusions, or kickstarting renal function, this solution plays a pivotal role in ensuring patients’ well-being.

Yet, it’s crucial to remember that each patient is unique, and the dosage and administration should always be orchestrated by a healthcare professional. In the journey toward better health, Neofleks 1/3 I.V. Infusion Icin Injection Solution stands as a testament to medical innovation and the pursuit of well-being.