Neo-Penotran Vaginal Ovul

Neo-Penotran Vaginal Ovul is a trusted gynecological medication, renowned for its effectiveness in combating a range of vaginal infections. As an azole antifungal agent, it plays a pivotal role in inhibiting the growth of fungi. In this comprehensive guide, we’ll explore its composition, indications, proper usage, contraindications, potential side effects, interactions, the time it takes…

Dosage form

Pack size





Generic Name (Ingredient)

1 For Vaginal Insert: Metronidazole 500 Mg Miconazole Nitrate 100 Mg

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Each Neo-Penotran tablet is a carefully crafted combination of two active ingredients:

  • Metronidazole (500mg): A potent antimicrobial agent known for its effectiveness against a broad spectrum of bacteria and certain parasites.
  • Miconazole nitrate (100mg): An antifungal agent that combats the growth of fungi.


Neo-Penotran is a versatile solution for several vaginal infections, including:

  • Vaginal Candidiasis: Commonly referred to as a yeast infection.
  • Anaerobic Vaginal Infections: Caused by anaerobic bacteria that thrive in environments with little oxygen.
  • Gardnerella Vaginalis: A bacterium associated with bacterial vaginosis.
  • Trichomonas Vaginalis: The parasite responsible for trichomoniasis, a sexually transmitted infection.
  • Mixed Vaginal Infections: When multiple pathogens are involved in an infection.


Utilizing Neo-Penotran Vaginal Ovul correctly is paramount for effective treatment. The following guidelines should be adhered to:

  • Administration: The medication is meant for intravaginal use. It should be inserted deep into the vagina while in a lying position.
  • Dosage: The typical regimen involves one tablet either in the evening for 14 days or one in the morning and one in the evening for 7 days. In cases of recurrent disease or vaginitis unresponsive to other treatments, a 14-day regimen with both morning and evening doses is recommended.


Certain conditions or situations warrant avoiding the use of Neo-Penotran:

  • Virgin Women: Neo-Penotran is generally not indicated for virgin women.
  • Hypersensitivity: Individuals with a history of hypersensitivity to any of the components of the drug should refrain from its use.
  • Health Conditions: The medication should be avoided in cases of porphyria, epilepsy, and severe liver dysfunction.
  • Pregnancy: During the first three months of pregnancy, Neo-Penotran is generally not recommended.

Side Effects

While Neo-Penotran is effective in treating vaginal infections, there are potential side effects to be aware of. These can include:

  • Vaginal Irritation
  • Abdominal Pain or Stomach Cramps
  • Metallic Taste
  • Gastrointestinal Effects: Such as constipation, dry mouth, diarrhea, loss of appetite, nausea, and vomiting.
  • Neurological Effects: These may encompass headache, dizziness, and mood swings.
  • Skin Reactions: Including skin rashes.


Neo-Penotran can interact with other substances and medications, including:

  • Alcohol
  • Oral Anticoagulants
  • Phenytoin
  • Disulfiram
  • Cimetidine

How Long Does It Take to See Results?

The timeline for experiencing the full therapeutic effects of Neo-Penotran is contingent upon the severity and type of infection. Common regimens include a 14-day evening application or a 7-day morning and evening application. In cases of recurrent disease, a 14-day regimen with both morning and evening doses is recommended. However, the precise duration for observing results varies among individuals.

Completing the full course of treatment is vital, even if symptoms ameliorate earlier, to ensure the complete eradication of the infection. Consulting with a healthcare provider is crucial for personalized guidance.

Can I Use It During Pregnancy?

The usage of Neo-Penotran during pregnancy requires careful consideration. It is generally not recommended during the first three months of pregnancy due to potential risks. After the first trimester, its use may be considered if deemed necessary but should be under the supervision of a healthcare professional. Pregnant individuals should always consult with their healthcare provider to weigh the potential benefits against risks.

Can I Use It While Breastfeeding?

Breastfeeding should be temporarily halted during Neo-Penotran treatment, as one of its active ingredients, metronidazole, can pass into breast milk. Resuming breastfeeding can typically occur 24 to 48 hours after the end of treatment. Nevertheless, it’s essential to consult with a healthcare provider for personalized advice regarding medication while breastfeeding.

Treating Vaginal Infections Naturally

While Neo-Penotran is a reliable treatment for vaginal infections, some individuals explore natural remedies in conjunction with or as an alternative to conventional medication. It’s important to note that natural remedies should complement medical treatment, not replace it. Here are some natural approaches:

  • Probiotics: Consuming probiotics, especially those containing Lactobacillus acidophilus, can promote a healthy vaginal environment.
  • Boric Acid: Some individuals use diluted boric acid for yeast infections. However, this should be done with caution.
  • Essential Oils: Certain essential oils, like tea tree oil, have antifungal properties. Always dilute them before use and consult a healthcare provider.
  • Dietary Changes: A balanced diet rich in nutrients can bolster the immune system.
  • Hygiene Practices: Maintaining good hygiene and avoiding douching are key.

Before trying any natural remedy, it’s crucial to consult with a healthcare provider for guidance and ensure it’s safe and appropriate for your situation.

Can Men Use Neo-Penotran?

Neo-Penotran is designed for intravaginal use and is primarily indicated for women. However, in cases where a woman’s sexual partner is also infected, particularly with Trichomonas vaginalis, partner treatment may be necessary to prevent reinfection. Male partners typically receive oral or injectable medications for such infections. Always consult with a healthcare provider for accurate diagnosis and guidance.


Neo-Penotran Vaginal Ovul provides several advantages in the treatment of vaginal infections:

  • Broad Spectrum of Action: Neo-Penotran is an azole antifungal agent effective against a variety of infections, including vaginal candidiasis, anaerobic vaginal infections, Gardnerella vaginalis, Trichomonas vaginalis, and mixed vaginal infections.
  • Effective Treatment: It has been demonstrated to effectively treat these infections, alleviating symptoms like itching, burning, abnormal discharge, swelling, and redness of the vagina.
  • Dual Active Ingredients: Each Neo-Penotran tablet combines Metronidazole and Miconazole nitrate, which work synergistically to combat the infection.
  • Ease of Use: Neo-Penotran is simple to use, designed for intravaginal administration.


In addition to the general precautions mentioned earlier, specific health conditions should be considered:

  • Liver Dysfunction: Avoid Neo-Penotran in cases of severe liver dysfunction, porphyria, epilepsy, and diseases of the peripheral and central nervous system.
  • Impaired Renal Function: Patients with seriously impaired renal function requiring hemodialysis should not use Neo-Penotran.
  • Hepatic Encephalopathy: Avoid Neo-Penotran in patients with hepatic encephalopathy.

It’s important to consult with a healthcare provider before starting any medication. They can provide personalized advice based on your specific situation and health condition.

Shelf Life

The shelf life of Neo-Penotran is up to 3 years. However, it’s crucial to check the expiration date on the packaging before use. If you’re unsure, consult a healthcare provider or pharmacist. Always store medications in a cool, dry place away from direct sunlight to maintain their effectiveness.


In conclusion, Neo-Penotran Vaginal Ovul is a valuable tool in the treatment of various vaginal infections. Its effectiveness, when used correctly and under the guidance of a healthcare provider, makes it a trusted choice for those seeking relief from the discomfort of these infections. Understanding its usage, potential side effects, and interactions, as well as considering natural remedies, ensures that individuals can make informed decisions regarding their health. Always prioritize consultation with a healthcare provider to ensure the most appropriate and effective treatment.

At a glance

Aspect Information
Composition – Metronidazole (500mg) – Miconazole nitrate (100mg)
Indications – Vaginal Candidiasis – Anaerobic Vaginal Infections – Gardnerella Vaginalis – Trichomonas Vaginalis – Mixed Vaginal Infections
Usage – Intravaginal use – Deep insertion while lying down – Dosage: 14 days evening application or 7 days morning and evening
Contraindications – Virgin Women – Hypersensitivity – Porphyria, Epilepsy, Severe Liver Dysfunction – First 3 Months of Pregnancy
Side Effects – Vaginal Irritation – Abdominal Pain – Metallic Taste – Gastrointestinal Effects – Neurological Effects – Skin Reactions
Interactions – Alcohol – Oral Anticoagulants – Phenytoin – Disulfiram – Cimetidine
How Long to See Results – Varied based on infection severity – Completing full course is essential – Consult healthcare provider for guidance
Pregnancy Use – Generally not recommended in the first 3 months – Consult healthcare provider after the first trimester
Breastfeeding – Temporary halt during treatment – Resume 24-48 hours after treatment ends – Consult healthcare provider
Natural Remedies – Probiotics – Boric Acid (with caution) – Diluted Essential Oils – Dietary Changes – Hygiene Practices
Usage in Men – Designed for women – Partner treatment may be necessary – Consult healthcare provider for male infections
Benefits – Broad Spectrum of Action – Effective Treatment – Dual Active Ingredients – Ease of Use
Precautions – Avoid in Specific Health Conditions – Consult healthcare provider for guidance
Shelf Life – Up to 3 years – Check expiration date before use – Store in a cool, dry place


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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