Motis Tablet

Motis Tablet, a medication classified under the group of dopamine receptor antagonists, holds a pivotal role in the realm of gastrointestinal motility. In this comprehensive overview, we unravel the core aspects of Motis Tablet, from its active ingredient to mechanisms of action, usage, and precautions. Let’s embark on this journey through the world of Motis.

Dosage form

Pack size


10 Mg



Generic Name (Ingredient)

Domperidone Maleate 12.72 Mg (Equivalent To 10 Mg Domperidone)

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Active Ingredient

At the heart of Motis Tablet lies Domperidone, the active ingredient. Each tablet encapsulates 10 milligrams of Domperidone, equivalent to 12.72 mg of Domperidone Maleate. This component is pivotal in igniting the therapeutic actions of Motis.

Empowering Gastrointestinal Motility

Motis Tablet serves a crucial purpose by stimulating gut motility in various conditions. These encompass:

  • Non-ulcer Dyspepsia: A common gastrointestinal disorder characterized by symptoms such as pain, fullness, and discomfort in the upper abdomen.
  • Oesophageal Reflux, Reflux Oesophagitis, and Gastritis: Conditions related to the regurgitation of stomach contents into the esophagus, leading to symptoms like heartburn and irritation of the esophagus.
  • Diabetic Gastroparesis: A condition where the stomach takes too long to empty its contents, often causing discomfort and digestive issues.
  • Functional Dyspepsia: A chronic disorder of sensation and movement in the upper digestive tract.

Furthermore, Motis Tablet plays a pivotal role in speeding barium transit in follow-through radiological studies. It is also a reliable companion in the prevention and symptomatic relief of acute nausea and vomiting induced by various causes, including cytotoxic therapy, radiotherapy, and antiparkinsonism therapy.

The Mechanism of Action

Domperidone, the dynamo behind Motis Tablet, operates as a gastrointestinal emptying adjunct and peristaltic stimulant. This is primarily achieved through its peripheral dopamine receptor blocking properties. The cascade of effects includes:

  • Facilitation of gastric emptying.
  • Decreased small bowel transit time.
  • Augmented esophageal and gastric peristalsis.
  • Reduction in esophageal sphincter pressure.

As an antiemetic, Domperidone’s actions encompass the blockade of dopamine receptors at both the chemoreceptor trigger zone and the gastric level.

Dosage Guidelines

Dosage parameters for Motis Tablet depend on age and specific medical needs:

  • For adults, the recommended dosage is 10 – 20 mg every 4 – 8 hours daily.
  • In the case of children, the dosage ranges from 0.2 – 0.4 mg/kg every 4 – 8 hours daily.

Motis Tablet should be administered 15 – 30 minutes before a meal. For conditions involving acute nausea and vomiting, the maximum treatment duration is 12 weeks.

Motis Side Effects

As with any medication, Motis Tablet carries the potential for side effects. However, it’s important to note that not everyone will experience these effects. Should you encounter any unusual symptoms while taking Motis Tablet, consulting your healthcare provider is paramount.


Prior to embarking on a Motis Tablet regimen, a discussion with your healthcare provider regarding your medical history is essential. Certain conditions may influence the medication’s utilization. Precautions include:

  • Allergies: If you have a history of allergies, especially to Domperidone or any inactive ingredients in the medication, inform your healthcare provider.
  • Pregnancy and Breastfeeding: Discuss the advantages and potential risks of Motis Tablet usage during pregnancy or while breastfeeding.
  • Medical History: Ensure your healthcare provider is aware of your medical history, particularly conditions like liver disease, heart problems, or gastrointestinal issues.
  • Interactions: Domperidone may interact with other medications, affecting its efficacy or increasing the risk of side effects. Provide your healthcare provider with a comprehensive list of all products you use, including prescription drugs, nonprescription drugs, and herbal products.

Furthermore, patients with diabetes or hypertension should be vigilant about potential drug interactions, and individuals with known hypersensitivity should exercise caution due to the risk of reactions or anaphylactic shock.

Intractions with other Medications

Motis Tablet can often be used in conjunction with other medications, but awareness of potential drug interactions is critical. Combining drugs can lead to effects like reduced efficacy, intensified side effects, or even dangerous overdoses. It is essential to share a complete list of all products you use, including prescription drugs, nonprescription drugs, and herbal products, with your healthcare provider to facilitate safe and effective treatment.

Timing and Benefits

The onset of action for Motis Tablet is notably swift. The antisecretory effect, or the reduction in gastric acid secretion, initiates within 1 hour of oral administration. The peak effect, signifying the zenith of the medication’s strength, surfaces between 1 to 3 hours.

The benefits of Motis Tablet span across various aspects:

  • Gastrointestinal Motility Improvement: Addressing conditions like non-ulcer dyspepsia, esophageal reflux, reflux oesophagitis, and gastritis.
  • Nausea and Vomiting Relief: Providing prevention and symptomatic relief from acute nausea and vomiting, whether triggered by cytotoxic therapy, radiotherapy, or antiparkinsonism therapy.

While these benefits offer promising relief, it’s essential to recognize that individual experiences may vary. Consulting a healthcare provider is crucial for tailored medical guidance.


The length of treatment with Motis Tablet fluctuates depending on the specific condition. For acute cases, such as nausea and vomiting, a standard treatment period is typically 12 weeks. In contrast, chronic conditions may necessitate a more extended course of treatment.

Your healthcare provider will determine the duration based on your unique needs and response to the medication. It’s crucial to adhere to your healthcare provider’s directives regarding treatment duration, even if symptoms improve.

A Medication’s Multifaceted Role

Motis Tablet, enriched with the prowess of Domperidone, serves as a formidable ally in the domain of gastrointestinal health. Its ability to enhance motility and alleviate distress in conditions like dyspepsia and nausea sets it apart. The swift onset of action further reinforces its utility.

Disclaimer: Nonetheless, to ensure the safe and effective use of Motis Tablet, always rely on the counsel of a healthcare provider. The information presented here offers a comprehensive overview but may not cover all possible applications, precautions, side effects, drug interactions, or specialized directives. Consult your healthcare provider for tailored medical advice and a deeper understanding of Motis Tablet’s role in your well-being

Parameter Motis Tablet
Active Ingredient Domperidone
Common Uses Gastrointestinal Motility Improvement, Nausea and Vomiting Relief
Dosage Guidelines Adults: 10 – 20 mg every 4 – 8 hours daily, Children: 0.2 – 0.4 mg/kg every 4 – 8 hours daily
Onset of Action Within 1 hour of oral administration, Peak effect within 1 to 3 hours
Benefits Swift action, Relief from gastrointestinal distress, Short-term and long-term application
Precautions Allergies, Pregnancy and Breastfeeding, Medical History, Interactions, Diabetes and Hypertension, Hypersensitivity



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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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