Metoart Con Injection Solution Iceren Injector 12.5 Mg

Metoart Con is a medication that comes in two formulations: Metoart Con 7.5 mg/0.1875 ml and Metoart Con 12.5 mg/0.3125 ml. In this in-depth exploration, we delve into its composition, working mechanisms, potential side effects, uses, and alternatives to provide you with a comprehensive understanding.

Dosage form

Pack size


12.5 Mg/0.3125Ml



Generic Name (Ingredient)

The 1 Ml Solution Contains 43.84 Methotrexate Disodium Equivalent To 40 Mg Methotrexate. The Injector Containing Each 0.3125 Ml Solution Contains 13.7 Mg Methotrexate Disodium Equivalent To 12.5 Mg Methotrexate.

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Metoart Con is centered around the active ingredient methotrexate, a powerful compound that plays a key role in its therapeutic effects. Specifically, “Metoart Con 12.5 mg/0.3125 ml” contains 12.5 mg of methotrexate, equivalent to 13.7 mg of methotrexate disodium per 0.3125 ml solution. In addition to methotrexate, the solution includes sodium chloride and water for injection as excipients.

Composition of Metoart Con

Component Quantity per Dose
Methotrexate 12.5 mg
Sodium Chloride
Water for Injection

Methotrexate’s Mechanism

Methotrexate is a multifaceted medication with various modes of action, depending on the condition it’s treating.

In Cancer and Psoriasis

Methotrexate interferes with DNA synthesis, primarily affecting rapidly proliferating cells, such as those in cancer and psoriasis. It achieves this by inhibiting dihydrofolate reductase (DHFR), an enzyme crucial for folic acid synthesis. Folic acid is essential for purine and pyrimidine synthesis, vital for protein, DNA, and RNA production.

In Rheumatoid Arthritis and Immune Disorders

In rheumatoid arthritis, methotrexate’s exact mechanism remains somewhat elusive. However, it is believed to impact immune function. It modulates immune responses by reducing T cell migration to the skin, curbing oxidative inflammation in immune cells like neutrophils and monocytes, and altering intercellular immune signaling. These effects result in reduced levels of inflammatory cytokines such as TNF-alpha, IL-10, and IL-12.

Inflammatory Conditions

Beyond cancer and psoriasis, methotrexate shines in treating inflammatory conditions like arthritis. It effectively reduces inflammation, leading to pain alleviation and the prevention of long-term joint and skin damage.

Side Effects

Yes, like many medications, Metoart Con has potential side effects, primarily attributed to its active ingredient, methotrexate. It’s crucial to note that not everyone experiences these side effects, but they should be considered. Here’s a breakdown:

Common Side Effects

  • Fever, chills, tiredness
  • Low blood cell counts
  • Mouth sores
  • Nausea, stomach pain
  • Abnormal liver function tests
  • Hair loss
  • Burning skin lesions

Serious Side Effects

  • Lung toxicity and damage
  • Liver damage
  • Kidney damage
  • Nerve damage
  • Increased susceptibility to serious infections
  • Low levels of certain blood cells
  • Severe gastrointestinal issues, including mouth sores

Should you or someone you know encounter any of these side effects while taking Metoart Con, it’s essential to promptly contact a healthcare professional. They can offer guidance on managing these side effects or adjusting the medication regimen as needed. Remember, this information is intended for general awareness and should not replace professional medical advice.

Metoart Con Uses

Metoart Con, powered by methotrexate disodium, finds application in various medical scenarios:

Rheumatoid Arthritis

Metoart Con is a valuable asset for managing severe, active rheumatoid arthritis in select adults.

Juvenile Idiopathic Arthritis

It extends its benefits to treating active polyarticular-course juvenile rheumatoid arthritis in children.


In the realm of dermatology, Metoart Con takes center stage for symptomatic control of severe, recalcitrant, and disabling psoriasis that doesn’t respond adequately to other treatments.

Psoriatic Arthritis

Metoart Con plays a crucial role in the treatment of psoriatic arthritis.

Crohn’s Disease

It’s a trusted ally in addressing Crohn’s disease, a challenging inflammatory bowel condition.

It’s imperative to underscore that Metoart Con should be used exclusively under the guidance of a healthcare professional. If you have queries or concerns about this medication, your healthcare provider is your best source for accurate information.

Exploring Alternatives

Indeed, there are alternative medications containing methotrexate, the same active ingredient as Metoart Con. Some of these alternatives include:

  • Trexall
  • Xatmep

These medications belong to various drug classes, such as antimetabolites, antipsoriatics, antirheumatics, and other immunosuppressants. They find applications in treating conditions like leukemia, specific cancers, severe psoriasis, and rheumatoid arthritis. However, please be aware that while these medications share the same active ingredient, they may not be interchangeable due to differences in dosage forms and strengths. Always seek counsel from a healthcare professional before initiating or modifying any medication regimen.

In Conclusion

In summary, Metoart Con is a medication of diverse capabilities, offering relief in the treatment of various conditions. Nevertheless, comprehensive information regarding “Metoart Con Injection Solution Iceren Injector 12.5 Mg” remains somewhat elusive from available sources.

To access accurate and detailed insights into this product, it’s advisable to consult with a healthcare professional or pharmacist. Your well-being is of paramount importance, and their expertise can guide you towards informed decisions regarding Metoart Con and its alternatives.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


The truth is that when we’re sick, or worried about getting sick, the internet won’t help.

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If diagnoses could be made simply from a textbook or an article on a website, we would all be doctors and treat ourselves. Nothing can replace the experience and knowledge of specially trained people. As in any field, in medicine there are unscrupulous specialists, differences of opinion, inaccurate diagnoses and incorrect test results.


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