Lorclast Film Coated Tablet

Allergic conditions can significantly impact an individual’s quality of life, causing disruptive symptoms that interfere with daily activities and sleep. Lorclast, a film-coated tablet, offers a comprehensive solution for patients suffering from allergic rhinitis, allergic rhinitis with asthma, and chronic idiopathic urticaria. This article provides a detailed overview, including its active ingredients, dosage, administration, packaging,…

Dosage form

Pack size

Potency

5 Mg/10Mg

Manufacturer

Nobel

Origin

Turkey

Generic Name (Ingredient)

Desloratadine 5 Mg Montelukast (10.40 Mg Equivalent To Montelukast Sodium) 10 Mg

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Description

Active Ingredients

Lorclast contains two active pharmaceutical ingredients: Desloratadine and Montelukast Sodium.

Desloratadine is a non-sedating, long-acting histamine antagonist with selective peripheral H1-receptor antagonist activity. This means that Desloratadine selectively blocks peripheral histamine H1-receptors, without causing the drowsiness often associated with older antihistamine medications. By targeting the peripheral histamine receptors, Desloratadine is able to provide effective allergy relief without the central nervous system (CNS) side effects.

Montelukast Sodium is an orally active compound that binds with high affinity and selectivity to the CysLT1 receptor. This receptor is found in various pro-inflammatory cells, including airway smooth muscle cells, airway macrophages, eosinophils, and certain myeloid stem cells. By targeting the CysLT1 receptor, Montelukast Sodium helps to reduce inflammation and alleviate allergy-related symptoms.

The combination of Desloratadine and Montelukast Sodium in Lorclast provides a comprehensive approach to managing allergic conditions, addressing both the histamine-mediated and leukotriene-mediated pathways involved in the allergic response.

Dosage and Administration

The recommended dose for adults and children over 15 years of age is one Lorclast tablet per day. Each tablet contains 5 mg of Desloratadine and 10 mg of Montelukast Sodium.

Lorclast can be taken at any time of the day, with or without food. The tablets should be swallowed whole and should not be crushed, dissolved, or chewed. This ensures the proper release and absorption of the active ingredients.

Packaging and Manufacturer

Lorclast is available in 30-tablet packages. Each tablet contains the recommended dosage of 5 mg Desloratadine and 10 mg Montelukast Sodium.

Lorclast is manufactured by Nobel, a pharmaceutical company based in Turkey. The company has a strong reputation for producing high-quality pharmaceutical products and adhering to strict manufacturing standards.

Drug Interactions

While specific interactions with Lorclast are not listed, it is important to note that any medication can potentially interact with others. Therefore, it is crucial for patients to inform their healthcare providers about all the medications they are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal products.

Desloratadine, one of the active ingredients in Lorclast, is a non-sedating, long-acting histamine antagonist with selective peripheral H1-receptor antagonist activity. This means that Desloratadine selectively blocks peripheral histamine H1-receptors, without causing the drowsiness often associated with older antihistamine medications.

Montelukast Sodium, the other active ingredient in Lorclast, is an orally active compound that binds with high affinity and selectivity to the CysLT1 receptor. This receptor is found in various pro-inflammatory cells, including airway smooth muscle cells, airway macrophages, eosinophils, and certain myeloid stem cells. By targeting the CysLT1 receptor, Montelukast Sodium helps to reduce inflammation and alleviate allergy-related symptoms.

It is important for patients to inform their healthcare providers about all the medications they are currently taking, as any medication can potentially interact with others. This allows the healthcare provider to assess the potential risks and benefits of Lorclast and make an informed decision about the most appropriate treatment plan.

Precautions

When taking Lorclast, there are several precautions to consider:

1. Use caution when taking Lorclast with alcohol, as the combination may increase the risk of side effects.
2. Do not give Lorclast to children less than 12 years of age, as the safety and efficacy of the medication have not been established in this age group.
3. If you are pregnant or breastfeeding, consult your doctor or pharmacist for advice before taking Lorclast, as the safety of the medication during pregnancy and lactation should be carefully evaluated.
4. If you have poor kidney function or a medical or familial history of seizures, talk to your doctor, pharmacist, or nurse before taking Desloratadine, as this may affect the safety and efficacy of the medication.

Lorclast Use During Pregnancy

The safety of Lorclast during pregnancy is an important consideration for healthcare providers and patients.

Desloratadine, one of the active ingredients in Lorclast, is an antihistamine that is generally considered safe for use during pregnancy. According to available resources, Desloratadine has not been shown to increase the risk of congenital abnormalities or other adverse outcomes when used during pregnancy.

Montelukast Sodium, the other active ingredient in Lorclast, is a leukotriene receptor antagonist used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Similar to Desloratadine, Montelukast Sodium is also generally considered safe for use during pregnancy, as it has not been associated with an increased risk of adverse pregnancy outcomes.

However, it is important to note that the safety of Lorclast during pregnancy can depend on various factors, including the stage of pregnancy and the individual’s overall health. Therefore, it is always best for pregnant patients to consult with their healthcare providers before taking any medication, including Lorclast, to ensure the safety and well-being of both the mother and the developing fetus.

Common Side Effects

Like all medications, Lorclast can cause side effects, although not everyone experiences them. Some of the common side effects associated with Lorclast include:

  • Headache
  • Dry mouth
  • Nosebleed
  • Sore throat
  • Mouth sores
  • Difficulty falling asleep or staying asleep
  • Nervousness
  • Weakness
  • Stomach pain
  • Diarrhea
  • Red or itchy eyes

It is important to note that this is not a complete list of side effects. Some individuals may experience other side effects that are not listed above. If you experience any side effects, or if you notice any side effects not listed, it is recommended to consult your doctor or pharmacist for advice on how to manage them.

Benefits of Lorclast Film Coated Tablet

Lorclast offers several therapeutic benefits for patients suffering from allergic conditions:

Allergy Relief: Lorclast is used to relieve the symptoms associated with allergic rhinitis (inflammation of the nasal passages caused by an allergy, hay fever, or allergy to dust mites) in adults and adolescents 12 years of age and older. These symptoms include sneezing, runny or itchy nose, itchy palate, and itchy, red, or watery eyes.

Urticaria Treatment: Lorclast is also used to relieve the symptoms of urticaria (a skin condition caused by an allergy), including itching and hives.

Long-Lasting Relief: The relief of these allergy-related symptoms lasts a full day, allowing patients to resume their normal daily activities and sleep.

In addition to the therapeutic benefits, Lorclast also offers advantages due to its film coating:

Simpler Process: The film coating process is simpler and, therefore, easier to automate compared to other coating methods, such as sugar coating.

Aesthetic Enhancement: The film coating enhances the elegance and glossy appearance of the coated tablets, making them more visually appealing.

Minimal Weight Increase: Film coating results in a minimal weight increase (typically 2–3% of the tablet core weight) compared to more than 50% with sugar coating.

Increased Flexibility: Film coating provides increased flexibility in formulations as a result of the availability of a wide range of coating materials and systems.

These benefits of the film coating, combined with the comprehensive allergy relief provided by the active ingredients, make Lorclast a compelling option for patients seeking effective and convenient management of their allergic conditions.

Conclusion

In conclusion, Lorclast is a film-coated tablet that combines the non-sedating antihistamine Desloratadine and the leukotriene receptor antagonist Montelukast Sodium to provide relief for patients suffering from allergic rhinitis, allergic rhinitis with asthma, and chronic idiopathic urticaria. With its recommended dosage, convenient administration, and generally considered safe use during pregnancy, it offers a comprehensive solution for managing these common and disruptive allergic conditions.

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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.

Cyberchondria

The truth is that when we’re sick, or worried about getting sick, the internet won’t help.

According to Wikipedia, cyberchondria is a mental disorder consisting in the desire to independently make a diagnosis based on the symptoms of diseases described on Internet sites.

Why you can't look for symptoms on the Internet

If diagnoses could be made simply from a textbook or an article on a website, we would all be doctors and treat ourselves. Nothing can replace the experience and knowledge of specially trained people. As in any field, in medicine there are unscrupulous specialists, differences of opinion, inaccurate diagnoses and incorrect test results.

 

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