Gisflor Saccharomyces Boulardii

Saccharomyces Boulardii, a probiotic yeast strain derived from Saccharomyces cerevisiae, holds a distinct place in the realm of gut health. Often hailed as a “friendly” microorganism, it possesses the remarkable ability to combat potentially harmful organisms, offering a multitude of benefits for gastrointestinal well-being.

Dosage form

Pack size


250 Mg



Generic Name (Ingredient)

Lyophilized Saccharomyces Boulardii 282.5 Mg

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Notice: despite the limited available information, this page provides information about the Gisflor ingredient: Saccharomyces Boulardii.

Unlike its more common counterparts, brewer’s and baker’s yeast, Saccharomyces Boulardii sets itself apart as a unique probiotic yeast. Its specialized properties make it a valuable asset in the realm of health and wellness.

Saccharomyces Boulardii Applications

Gastrointestinal Guardian

Saccharomyces Boulardii comes to the forefront as a versatile remedy for various gastrointestinal disorders. Among its primary applications are:

  1. Traveler’s Diarrhea: Providing relief from the inconvenience of traveler’s diarrhea.
  2. Antibiotic-Associated Diarrhea: Offering a solution to diarrhea often triggered by antibiotic use.
  3. Irritable Bowel Syndrome: Aiding in the management of irritable bowel syndrome.
  4. Inflammatory Bowel Diseases: Extending its benefits to conditions like Crohn’s disease and ulcerative colitis.

Beyond the Gut

The reach of Saccharomyces Boulardii extends beyond gastrointestinal matters. It is also recognized for its efficacy in:

  1. Cholesterol Management: Contributing to the reduction of high cholesterol levels.
  2. Combatting Infections: Playing a pivotal role in addressing infections caused by Helicobacter pylori (H. pylori), Clostridium difficile (C. difficile), and Candida albicans (C. albicans).

Saccharomyces Boulardii

Saccharomyces Boulardii’s effectiveness shines through based on comprehensive data. According to the Natural Medicines Comprehensive Database, it demonstrates efficacy in managing a spectrum of conditions, including diarrhea, antibiotic-associated diarrhea, infections, and travelers’ diarrhea.

Saccharomyces Boulardii Side Effects

While generally well-tolerated, Saccharomyces Boulardii can present mild side effects, including bloating and flatulence. For individuals experiencing persistent discomfort, prompt consultation with healthcare professionals is advised.


The recommended dosage of Saccharomyces Boulardii hinges on individual factors, chiefly age and form. Here’s a comprehensive breakdown:

For Adults

  • Oral Capsules: A standard adult dose comprises one 250 mg oral capsule taken twice daily.
  • Oral Powder for Reconstitution: Similarly, one packet of 250 mg oral powder, reconstituted, is consumed twice daily.
  • Clinical Doses: In some cases, clinical trials have employed doses not exceeding 1,000 mg per day.
  • Alternate Dosing: For specific situations, an adult may opt for 500-1000 mg daily for four weeks.

For Children

  • Oral Capsules: Children’s dosages mirror those of adults, involving one 250 mg oral capsule twice daily.
  • Oral Powder for Reconstitution: Like adults, children can also use one packet of 250 mg oral powder reconstituted, taken twice daily.
  • Clinical Dosing: Clinical trials have explored doses ranging from 250 to 500 mg per day.
  • Alternative Regimens: Children may also consider 250-500 mg daily for up to four weeks.

It is paramount to emphasize that any new treatment regimen should commence under the guidance of a healthcare provider, taking individual needs into account.

The Shelf Life

Understanding the shelf life of Saccharomyces Boulardii supplements is essential for maintaining their efficacy. Vital considerations include:

  • Refrigeration: Some supplements necessitate refrigeration and may arrive with a cold pack. However, they can often endure up to five days without refrigeration.
  • Room Temperature: Specific Saccharomyces Boulardii probiotics, particularly those containing 10 Billion CFU of S. Boulardii, thrive at room temperature and retain potency for up to two years.
  • Shelf-Stable Varieties: Certain Saccharomyces Boulardii probiotics, as well as soil-based probiotics, do not require refrigeration but may benefit from it for prolonged shelf life.

For precise guidance on storage, consulting the product packaging is advisable. In cases of uncertainty, healthcare providers and pharmacists can offer valuable insights.

Timing Matters

A noteworthy aspect of Saccharomyces Boulardii is its adaptability regarding food consumption. It can be taken with or without meals, offering flexibility to users. Research indicates that Saccharomyces Boulardii microorganisms remain equally effective whether ingested with or without food. However, maintaining consistency in administration is of paramount importance. In scenarios where Saccharomyces Boulardii supplements are consumed alongside antibiotics, simultaneous intake is recommended.

Optimal Timing 

Determining the ideal time to consume Saccharomyces Boulardii supplements rests on individual preferences and routines. Various sources suggest distinct timings:

  • Morning Routine: Commencing the day with Saccharomyces Boulardii intake before breakfast.
  • Evening Choice: Opting for an evening schedule, taking the supplement before bedtime.
  • Mealtime Consistency: For users consuming multiple sachets, one with each meal and one before retiring for the night.
  • Robust Strain: Saccharomyces Boulardii’s resilience allows flexibility, permitting consumption with or without food.

Consistency in intake routines holds greater significance than the specific timing chosen. It is always prudent to initiate any new treatment regimen following consultation with a healthcare provider.

In Conclusion

In closing, Saccharomyces Boulardii stands as a well-tolerated probiotic with a rich clinical history in addressing diverse gastrointestinal concerns. Nevertheless, like any supplement or medication, its usage should commence under the supervision and guidance of a healthcare provider. The individualized approach ensures not only the harnessing of its benefits but also the preservation of personal well-being. Remember, informed medical consultation remains an essential cornerstone in the pursuit of health and vitality.

At a glance

Attribute Information
Probiotic Type Yeast (Saccharomyces cerevisiae)
Key Function Combatting harmful organisms
Distinctiveness Different from brewer’s and baker’s yeast
Common Uses Addressing gastrointestinal disorders
Other Applications Lowering cholesterol, combating infections
Effectiveness Effective against diarrhea and associated conditions, among others
Side Effects Bloating, flatulence
Dosage Recommendations Vary by age and form
Shelf Life Varies by product and storage conditions
Compatibility with Food Can be taken with or without meals
Optimal Timing Morning, evening, or with meals


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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