Geroxalen Capsule

In the realm of dermatology, Geroxalen Capsule assumes a pivotal role, offering respite to individuals grappling with severe and very severe psoriasis vulgaris, commonly referred to as plaque psoriasis. This comprehensive guide delves into the depths of this medication, elucidating its composition, workings, potential side effects, and indispensable precautions.

Dosage form

Pack size


10 Mg



Generic Name (Ingredient)

Each Capsule Contains 10 Mg Of 8-Methoxyperoral (Methoxaline).

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Unveiling Geroxalen Capsule

Geroxalen is a medicinal beacon, containing the active ingredient 8-methoxypsoralen, also known as methoxsalen, meticulously crafted to combat the challenges posed by severe psoriasis vulgaris. Available in capsule form, each encapsulation harbors a therapeutic dose of 10 mg of 8-methoxypsoralen. These capsules come packaged in boxes, with each box comprising 50 capsules, neatly organized in blisters of 10.


Methoxsalen, the driving force behind Geroxalen, also recognized as 8-methoxypsoralen, stands as a formidable ally in the fight against a spectrum of dermatological adversaries, including psoriasis, eczema, vitiligo, and select cutaneous lymphomas. Marketed under the brand names Oxsoralen, Uvadex, and 8-Mop, Methoxsalen, when combined with exposure to ultraviolet (UVA) light, emerges as a potent treatment modality.

How Methoxsalen Operates

Methoxsalen’s efficacy unfolds through its unique mechanism of action, whereby it heightens the skin’s sensitivity to ultraviolet light A (UVA). This synergistic interplay serves to curtail the excessive proliferation of skin cells, a hallmark of psoriasis. By modulating how skin cells interact with UVA radiation, Methoxsalen offers a beacon of hope for individuals seeking respite from the clutches of this disease.

Side Effects

While Methoxsalen is a valuable ally, it’s essential to be cognizant of potential side effects, some of which could warrant immediate attention. These may encompass:

1. Skin Redness and Discomfort

Severe skin redness within 24 hours following UVA treatment, coupled with swelling, severe itching, or pronounced skin discomfort, requires vigilant monitoring.

2. Ocular Concerns

Methoxsalen may impact vision, leading to blurred vision, tunnel vision, eye pain, swelling, or the perception of halos around lights. Any such visual changes demand prompt medical evaluation.

3. Psoriasis Aggravation

In some instances, Methoxsalen treatment may paradoxically worsen psoriasis. Any exacerbation of symptoms necessitates immediate consultation with a healthcare professional.


Prior to embarking on Methoxsalen therapy, several crucial precautions merit attention:

1. Sensitivity to Light

Methoxsalen should be avoided if one exhibits heightened sensitivity to light, has existing lens damage in the eye, or a history of skin cancer. The potential adverse effects on vision and skin mandate careful consideration.

2. Post-Treatment Sun Avoidance

Post-UVA treatment, natural sunlight should be avoided for up to 48 hours, owing to Methoxsalen’s lingering effects.

3. Age Consideration

Geroxalen should not be administered to children under 12 years of age.

4. Prior Exposure to Risk Factors

If previous exposure to risk factors like coal tar treatment, arsenic preparations, UVB or X-ray radiation therapy has occurred, the suitability of PUVA therapy should be thoroughly evaluated.

Availability and Prescription

Geroxalen, an indispensable therapeutic tool, is available exclusively by prescription. This ensures that its administration is under the careful guidance of healthcare professionals, tailoring treatment to individual needs. This medication is not recommended for use in children younger than 12 years, reinforcing the need for prudence in its application.


In the ever-evolving field of dermatological care, Geroxalen Capsule shines as a valuable resource, offering solace to those battling the relentless grip of severe psoriasis vulgaris. While it promises relief, the importance of approaching its usage with caution cannot be overstated. Prudent adherence to precautions and professional guidance ensures not only the efficacy of Geroxalen but also the safety and well-being of those it endeavors to assist.


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