Delix Plus Tablet 5Mg

DELIX 5 mg PLUS is a drug containing two different active substances (ramipril and hydrochlorothiazide) that help lower blood pressure.

Of these active substances, ramipril belongs to a group of drugs called Angiotensin Converting Enzyme Inhibitors (ACE Inhibitors). This active substance lowers blood pressure by acting on the heart and blood vessels.

The other active substance, hydrochlorothiazide, belongs to the group of diuretic drugs from the thiazide class. By acting on the kidneys, it increases the frequency of urination and, in this way, lowers blood pressure. The blood pressure lowering effects of both substances complement each other.

  • DELK 5 mg PLUS is available in blister pack containing 28 notched tablets. There is another form on the market called DELK 2.5 mg PLUS, containing 28 notched tablets.

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Description

Things to consider before using DELIX PLUS

DO NOT USE DELIX PLUS in the following situations

If,

    • If you have hypersensitivity (allergy) to ramipril and hydrochlorothiazide, which are the active ingredients of DELIX 5 mg PLUS, or to another ACE inhibitor or other diuretics from the thiazide group, or to sulfonamide group antibiotics or to any of the other ingredients of the drug,
    • if you have ever had angioedema (swelling of the skin or airways)
    • if you have severe kidney dysfunction
    • If you are on dialysis or have any type of blood filtration. Depending on the machine used, DELIX 5 mg PLUS may not be suitable for you.
    • If you have a vascular stenosis that will reduce the blood flow to your kidneys,
    • If you have a significant disturbance in salt balance in your body (such as low potassium, sodium or calcium levels)
    • if you have severe liver dysfunction
    • If you have diabetes (diabetes) or kidney failure and are taking the high blood pressure medicine called aliskiren
    • Do not use DELIX 5 mg PLUS together with a blood pressure lowering drug containing angiotensin receptor antagonist, if you have diabetes and a related kidney disorder.
    • In the last 6 months of your pregnancy,
    • If you are breastfeeding your baby Do not use DELK 5 mg PLUS.

 

There is not enough experience with the use of DELK 5 mg PLUS in children. DELK 5 mg PLUS should not be used in children.

USE DELIX PLUS CAREFULLY in the following situations

Treatment with DELIX 5 mg PLUS requires continued medical supervision.

If,

    • If swelling of the face, arms or legs, lips, tongue or throat, difficulty in breathing, palpitations and difficulty swallowing (angioedema) or abdominal pain (nausea or vomiting may be accompanied by pain) occur during treatment; Stop the treatment immediately and apply to the emergency department of the nearest hospital.
    • If you have severe hypertension. Your doctor may want to follow you closely during the initial period of treatment.
    • If you have heart failure. Your doctor may want to follow you closely during the initial period of treatment.
    • If you have ever had any problems with the heart or heart valves, such as a murmur or block. Your doctor may want to follow you closely during the initial period of treatment.
    • If you have heart, liver or kidney problems, you should use it with caution.
    • if you have previously been treated with diuretics (diuretics). Your doctor may want to follow you closely during the initial period of treatment.
    • If you have had problems with salt balance (such as a rise or fall in sodium or potassium levels) caused by dehydration from vomiting or diarrhea, or following a severely restricted diet.
    • If you have a problem with blood flow due to narrowing or blockage of your heart or brain vessels. Your doctor may want to follow you closely during the initial period of treatment.
    • If you are of advanced age. Your doctor may want to evaluate your kidney function before starting treatment.
    • If you have a problem with your kidneys. Your doctor will evaluate your kidney function before prescribing DELK 5 mg PLUS and will continue to monitor you during treatment. If you have problems with the kidneys, your doctor may need to readjust the dose of the medicine.
    • If you use it together with angiotensin receptor antagonist (AIIRA) or aliskiren-containing drugs used in the treatment of high blood pressure, there is evidence of a risk of low blood pressure (hypotension), increased blood potassium level (hyperkalemia) and decreased kidney function compared to use alone. Concomitant use of these drugs is not recommended.
    • If you have a disease such as lupus or scleroderma, which concerns the tissues in which collagen, a flexible protein that fills the spaces between tissue cells, enters into its structure. Your doctor may want to monitor your blood and urine, especially if you have concomitant kidney problems and are taking other medications.
    • If you are being treated to reduce allergy to bee and insect stings

 

Pregnancy

    • During treatment, your doctor may order regular monitoring of your blood sodium, potassium, calcium, uric acid and glucose levels and order blood tests to detect a possible decrease in the number of white blood cells that protect your body against infections.
    • If you need surgery or anesthesia, tell your doctor or dentist that you are using DELIX 5 mg PLUS; Your treatment may need to be changed to match the medicine you are taking.
    • The hydrochlorothiazide contained in DELIX 5 mg PLUS can cause temporary visual impairment (myopia) or eye pressure (acute angle-closure glaucoma). If symptoms such as decreased visual acuity or eye pain occur within the first few hours to a few weeks after you start using DELIX 5 mg PLUS, stop using the drug and consult your doctor so that the necessary treatment can be started as soon as possible. Failure to start treatment immediately can result in permanent vision loss. Those with a previous history of penicillin or sulfonamide allergy are at higher risk of developing this condition.

 

If these warnings apply to you, even at any time in the past, please consult your doctor.

Using DELIX PLUS with food and drink

Alcohol intake during the use of DELIX 5 mg PLUS may cause dizziness and lightheadedness. If you have questions about how much alcohol you can drink while using DELIX 5 mg PLUS, consult your doctor. Because alcohol can increase the blood pressure lowering effect of DELIX 5 mg PLUS.

Food does not affect the absorption of DELİX 5 mg PLUS. Swallow the tablets with sufficient liquid (1 glass of water) during meals, before or after meals, in the amount recommended by your doctor.

Pregnancy

Consult your doctor or pharmacist before using this medication.

If you are thinking of becoming pregnant (or if you are pregnant), be sure to tell your doctor. An effective method of contraception should be used while using the drug.

You should not take DELIX 5 mg PLUS during the first 12 weeks of your pregnancy. Do not use DELIX 5 mg PLUS after the 12th week, because use during pregnancy may harm your baby.

If you become pregnant while using DELIX 5 mg PLUS, tell your doctor immediately. Before the planned pregnancy, a transition to an appropriate alternative treatment should be made.

If you realize that you are pregnant during your treatment, consult your doctor or pharmacist immediately.

Breast-feeding

Consult your doctor or pharmacist before using this medication.

If you need to be treated with DELIX 5 mg PLUS while breastfeeding, you should stop breastfeeding to protect the baby from small amounts of ramipril excreted in breast milk.

You should not use DELIX 5 mg PLUS during breastfeeding.

Vehicle and machine use

You may feel dizzy while using DELIX 5 mg PLUS. You may feel dizzy when you start DELIX 5 mg PLUS or when you switch to a higher dose. If you experience dizziness, do not drive or use machinery.

Important information about some of the ingredients of DELIX PLUS

If you are not sensitive to the excipients in DELK 5 mg PLUS, no adverse effects are expected due to these substances.

Concomitant use with other drugs

Inform your doctor if you are taking any of the following drugs, as they may reduce the effect of DELIX 5 mg PLUS:

    • Medicines such as ibuprofen and indomethacin, aspirin used to reduce pain and inflammation (non-steroidal anti-inflammatory drugs (NSAIDs))
    • Medicines such as ephedrine, noradrenaline and adrenaline used to treat low blood pressure, shock, heart failure, asthma or allergies. Your doctor will want to measure your blood pressure.

 

Inform your doctor if you are taking any of the following medicines, as the possibility of side effects may increase when used together:

    • Angiotensin receptor antagonist (AIIRA) or aliskiren-containing drugs used in the treatment of high blood pressure (increases the risk of low blood pressure (hypotension), increased potassium level in the blood (hyperkalemia) and kidney function changes compared to use alone)
    • Medicines such as ibuprofen and indomethacin, aspirin used to reduce pain and inflammation (non-steroidal anti-inflammatory drugs (NSAIDs))
    • Medicines used in cancer treatment (chemotherapy)
    • Medicines such as cyclosporine used to prevent organ rejection after transplant
    • diuretics (diuretics) such as furosemide
    • ACTH (used to treat adrenal glands)
    • amphotericin B (used to treat fungal infections)
    • Medicines that increase the amount of potassium in your blood, such as spironolactone, triamterene, amiloride, potassium salts, and heparin (blood thinners)
    • Steroid drugs such as prednisolone used to treat inflammation
    • Allopurinol (used to lower the amount of uric acid in your blood)
    • Procainamide (for heart rhythm disorders)
    • Corticosteroids, carbenoxolone, large amounts of licorice root, laxatives (with prolonged use) and other urinary potassium-depleting agents: The risk of low blood potassium level increases.
    • Cardiac drugs containing digitalis (eg digoxin): As a result of changes in salt balance (eg, decreased blood potassium and magnesium levels), the risk of digitalis toxicity (toxicity) increases.
    • Methyldopa (a medicine used to treat high blood pressure): Hemolysis (destruction of red blood cells) may occur.
    • Orally administered ion exchangers (eg cholestyramine): Absorption of hydrochlorothiazide is reduced.
    • Curare-type muscle relaxants: The muscle relaxant effect may be stronger and longer lasting.
    • Carbamazepine (used to treat epilepsy).

 

Inform your doctor if you are using the following drugs, as they may interact with DELIX 5 mg PLUS:

    • Oral medications used in the treatment of diabetes, such as sugar reducers and insulin (follow your blood sugar levels closely during DELİX 5 mg PLUS treatment)
    • The risk of developing angioedema (swelling of the face, lips, eyes or throat) may be increased if you are taking vildagliptin (an oral sugar reducer) or medicines such as temsirolimus, everolimus, sirolimus (used in the treatment of cancer and organ transplant) with DELIX 5 mg PLUS.
    • Lithium (used for mental health problems). DELIX 5 mg PLUS may increase the amount of lithium in your blood. Your doctor will want to closely monitor the amount of lithium in your blood.
    • Quinine (used to treat malaria)
    • Iodine-containing drugs (used in radiological imaging procedures)
    • Penicillin (anti-inflammatory drug)
    • Oral blood thinners (such as warfarin)

 

Effect on laboratory and diagnostic tests:

Parathyroid function tests: Hydrochlorothiazide stimulates the reabsorption of calcium from the kidneys and may cause elevated blood calcium levels. This should be taken into account when performing parathyroid function tests.

How to use DELIX PLUS?

Instructions for proper use and dose/frequency of administration

Take care to use DELIX 5 mg PLUS as your doctor has told you. If you have questions, consult your doctor and pharmacist.

In the treatment of hypertension (high blood pressure), the usual starting dose is 1/2 DELK 5 mg PLUS once a day.

If necessary, the dose can be increased at intervals of 2-3 weeks. Maximum allowable daily dose: 2 DELIX 5 mg PLUS.

A daily dose is usually recommended to be administered as a single dose in the morning.

In most cases, after 1/2 to 1 DELIX 5 mg PLUS tablet daily, blood pressure will drop sufficiently.

Application route and method

DELIX 5 mg PLUS is taken orally.

Take the daily dose as a single dose in the morning.

Take the tablets at the same time each day. Taking your tablets at the same time each day will give you the best effect on your blood pressure. It will also help you remember when to take the tablets.

DELIX 5 mg PLUS should be swallowed whole with a sufficient amount of liquid (approximately 1/2 glass of water) before/after or during the meal.

Unless your doctor recommends otherwise follow these instructions.

different age groups

Use in the elderly:

The starting dose should be lower and the dose should be increased more slowly, especially in very elderly and frail patients, since side effects are more likely to occur. Since there is a risk of decreased kidney function in the elderly, caution should be exercised during use in the elderly. Your doctor may want to evaluate your kidney function before starting treatment.

Special use cases

Severe kidney failure:

DELIX 5 mg PLUS is excreted through the kidneys. Do not use this medicine if you have severe kidney failure or if you are on dialysis.

Moderate renal failure:

In case of moderate renal impairment, DELIX 5 mg PLUS should be used with caution. In this case, your doctor may reduce the dose or interrupt the treatment.

According to your doctor’s recommendations, start treatment with only 1.25 mg of ramipril per day. After gradually increasing the dose of ramipril, combination therapy is started with 1/2 DELIX 5 mg PLUS daily. Maximum allowable daily dose: 1 DELIX 5 mg PLUS.

Severe hepatic failure:

Do not use DELIX 5 mg PLUS tablet if you have severe liver failure.

Mild to moderate hepatic impairment:

If you have mild to moderate hepatic impairment, your doctor will start you on treatment with DELIX 5 mg PLUS Tablet under close medical supervision. The highest permissible daily dose is 1/2 DELIX 5 mg PLUS tablet. If you have mild to moderate hepatic impairment, do not use the drug in higher doses.

If you are using diuretic medication:

According to your doctor’s recommendations, at least 2-3 days or more before you start DELIX 5 mg PLUS treatment, you should stop or at least reduce the dose of the diuretic drug you use.

If it is not possible to stop the drug, your doctor will start your treatment with the minimum dose of DELIX (V2 DELIX 2.5 mg per day). In case of subsequent changes to the initial daily dose, it is recommended that DELIX 5 mg PLUS be more than 1/2 tablet.

If you have the impression that the effect of DELIX 5 mg PLUS is too strong or weak, talk to your doctor or pharmacist.

If you use more DELIX PLUS than you should

Inform your doctor or go to the nearest hospital. Do not drive while going to the hospital, reach the hospital with the help of someone or call an ambulance. Take the box of your medicine with you so that your doctor will know how much medicine you have taken.

Overdose manifests itself with symptoms that progress to extreme low blood pressure, excessive decrease in heart rate, heart rhythm disorders, confusion and coma.

If you have used more than you should use DELIX 5 mg PLUS, talk to a doctor or pharmacist.

If you forget to use DELIX PLUS

If you forget to take a single dose of DELIX 5 mg PLUS, take the next regular dose on time.

Do not take a double dose to make up for forgotten doses.

Effects that may occur when treatment with DELIX PLUS is terminated

If you stop DELIX 5 mg PLUS treatment without your doctor’s approval, the beneficial effects of the treatment may disappear and your blood pressure may rise again

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Additional information

Dosage form

Pack size

Potency

5 Mg

Manufacturer

Origin

Generic Name (Ingredient)

Ramipril 5 Mg

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Cyberchondria

The truth is that when we’re sick, or worried about getting sick, the internet won’t help.

According to Wikipedia, cyberchondria is a mental disorder consisting in the desire to independently make a diagnosis based on the symptoms of diseases described on Internet sites.

Why you can't look for symptoms on the Internet

If diagnoses could be made simply from a textbook or an article on a website, we would all be doctors and treat ourselves. Nothing can replace the experience and knowledge of specially trained people. As in any field, in medicine there are unscrupulous specialists, differences of opinion, inaccurate diagnoses and incorrect test results.

UNDER NO CIRCUMSTANCES PLEASE DO NOT USE THE INTERNET TO DIAGNOSE ANY KIND OF HEALTH-RELATED PROBLEMS OR DISEASES!