Cleocin T Topikal Solution

Delving into the intricacies of skincare, “Cleocin – T Topikal Solution” emerges as a potent medication designed to combat severe acne. This article aims to unravel the composition, mechanism of action, pharmacokinetics, microbiology, potential side effects, contraindications, and usage guidelines of this topical solution. As we navigate through its benefits, application methods, alternatives, precautions, and…

Dosage form

Pack size


%1 30Ml



Generic Name (Ingredient)

In 1 Ml Of Solution, Clindamycin Phosphate Is Equivalent To 10 Mg Of Clindamycin.

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Understanding the makeup of “Cleocin T Topikal Solution” is crucial for comprehending its efficacy. The solution comprises isopropyl alcohol (50% v/v), propylene glycol, and water. Additionally, the gel variant incorporates allantoin, carbomer 934P, methylparaben, polyethylene glycol 400, propylene glycol, sodium hydroxide, and purified water.

The lotion formulation encompasses cetostearyl alcohol (2.5%), glycerin, glyceryl stearate SE (with potassium monostearate), isostearyl alcohol (2.5%), methylparaben (0.3%), sodium lauroyl sarcosinate, stearic acid, and purified water.

Variant Key Ingredients
Solution Isopropyl alcohol, propylene glycol, water
Gel Allantoin, carbomer 934P, methylparaben, and more
Lotion Cetostearyl alcohol, glycerin, methylparaben, and more

Mechanism of Action

The mechanism of action of clindamycin, the active ingredient in “Cleocin T Topikal Solution,” remains elusive in treating acne vulgaris. However, it exhibits bacteriostatic properties by inhibiting bacterial protein synthesis, binding to the 23S RNA of the 50S subunit of the ribosome.

Pharmacokinetics: Navigating Absorption and Distribution

Following multiple topical applications, minimal levels of clindamycin are detected in the serum (0–3 ng/mL). Less than 0.2% of the dose is recovered in urine as clindamycin, emphasizing the localized impact of the solution.

Microbiology: Tackling Propionibacterium acnes

While clindamycin showcases activity against Propionibacterium acnes in vitro, the clinical significance of this remains uncertain. Resistance to clindamycin is primarily attributed to specific modifications in the 23S ribosomal RNA.

Side Effects

“Cleocin T Topikal Solution” may induce both common and serious side effects, necessitating a vigilant approach.

Common Side Effects:

  • Burning, itching, dryness, redness, oily skin, skin peeling, or other irritation of treated skin.

Serious Side Effects:

  • Severe redness, itching, or dryness of treated skin areas.
  • Severe stomach pain, watery or bloody diarrhea (even occurring months after the last dose).

Other Side Effects:

  • Blistering, peeling, or loosening of the skin.
  • Hives, itching, skin rash.
  • Joint or muscle pain.
  • Rash with flat or raised lesions on the skin.
  • Red irritated eyes.
  • Red skin lesions, often with a purple center.
Type Examples
Common Burning, itching, redness
Serious Severe redness, stomach pain, bloody diarrhea
Other Blistering, hives, joint pain, rash with lesions, red eyes


“Cleocin T Topikal Solution” is contraindicated in individuals with a history of hypersensitivity to clindamycin or lincomycin, regional enteritis or ulcerative colitis, and a history of antibiotic-associated colitis.

Cleocin T Interactions

The solution may interact with erythromycin, whether applied topically or taken orally.

Pregnancy and Breastfeeding

While “Cleocin T Topikal Solution” may be used during pregnancy if prescribed, its passage into breast milk remains uncertain. Prudent consultation with healthcare providers is advised.


Application of a thin film twice daily to the affected area is the recommended dosage for optimal results.


In the realm of acne treatment, “Cleocin T Topikal Solution” stands as a formidable contender. Its well-defined composition, targeted mechanism of action, and meticulous precautions position it as a valuable tool in the hands of healthcare providers and individuals combating severe acne. As we navigate the nuanced landscape of skincare, the importance of personalized advice and vigilant application cannot be overstated.

“Cleocin T Topikal Solution” unveils a path to clearer skin, guided by medical expertise and a commitment to individual well-being.

Table: Summary of Cleocin

Aspect Details
Composition Isopropyl alcohol, propylene glycol, clindamycin
Mechanism of Action Bacteriostatic action on 23S RNA of bacterial ribosome
Pharmacokinetics Low systemic absorption, localized impact
Microbiology Activity against Propionibacterium acnes
Side Effects Common, Serious, and Other side effects
Contraindications Hypersensitivity, enteritis, antibiotic-associated colitis
Interactions Potential interaction with erythromycin
Usage During Pregnancy Recommended under prescription during pregnancy
Dosage Apply thin film twice daily to affected area
Conclusion “Cleocin T Topikal Solution” offers a path to clearer skin, guided by medical expertise and personalized care.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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