Candexil Plus Tablet 16 Mg

Candexil Plus is a pharmaceutical wonder available in tablet form, offered in two distinct packaging options: a pack of 28 tablets and a larger pack of 84 tablets. It’s essential to note that this medication is exclusively distributed through pharmacies.

Dosage form

Pack size


16 Mg



Generic Name (Ingredient)

Kandesartan Cilexetil 16 Mg Hydrochlorothiazide 12.5 Mg

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Active Ingredients

At the heart of Candexil Plus are two powerful active ingredients: Kandesartan sileksetil (16 mg) and Hidroklorotiyazid (12.5 mg), each playing a pivotal role in its pharmacological profile.


DEVA Holding is the distinguished manufacturer behind the creation of Candexil Plus, ensuring a high standard of quality and efficacy.

Different Variants

In addition to the 16 mg/12.5 mg dosage, Candexil Plus also offers an alternative potency: the 32 mg/12.5 mg dosage. This range of options allows for tailored treatment based on individual needs.

Side Effects

Candexil Plus, fortified with Kandesartan sileksetil and Hidroklorotiyazid, may introduce several side effects. The most frequently reported among them include:

  • High potassium levels
  • Headache
  • Back pain
  • Dizziness
  • Cold- or flu-like symptoms, such as fever, cough, sneezing, sore throat, and nasal congestion
  • Abnormal kidney test results

Moreover, it’s essential to be mindful of specific contraindications. Candexil Plus is not recommended for patients with severe hepatic impairment and/or cholestasis. Furthermore, its safety and efficacy have not been established for children. In the elderly population, dosage adjustments are typically unnecessary.

For a more exhaustive understanding of the potential side effects, it is highly advisable to consult a healthcare professional. This list represents common reactions, but individual responses may vary.

Timeframe of Effectiveness

Upon the administration of a single dose of Candexil Plus, the antihypertensive effect typically commences within 2 hours. In the context of continuous treatment, the most significant reduction in blood pressure is achieved within 4 weeks and is sustained during long-term use. It’s crucial to emphasize that the precise timing can differ based on individual health factors, warranting a personalized consultation with a healthcare provider for accurate guidance.

Dosage Recommendations

The recommended dosage for Candexil Plus involves a single tablet administered once daily. The majority of the antihypertensive effect manifests within 4 weeks of treatment initiation. However, it’s imperative to adhere to the healthcare provider’s specific instructions regarding dosage and frequency, as these may be subject to individual health considerations. It’s always prudent to consult a healthcare professional for tailored advice.

Candexil Plus Benefits

Candexil Plus serves as an invaluable tool in the management of high blood pressure, scientifically known as hypertension. Its active constituents, Candesartan and Hydrochlorothiazide, synergize to provide a dual-action approach to blood pressure control.

Mechanism of Action

Candesartan operates as an angiotensin II receptor blocker (ARB), effectively inhibiting the action of a vasoconstrictor in the body, leading to vasodilation. This, in turn, results in lowered blood pressure and an enhanced supply of blood and oxygen to the heart.

Hydrochlorothiazide, on the other hand, functions as a diuretic, often referred to as a “water pill.” By increasing urine production and reducing water retention, it contributes to the lowering of blood pressure.

Realizing the Benefits

The combination of Candesartan and Hydrochlorothiazide within Candexil Plus delivers a dual benefit. It relaxes blood vessels, reducing resistance, and simultaneously decreases water retention, leading to effective blood pressure reduction. This not only minimizes the risk of hypertension-related complications but also promotes overall cardiovascular health.

It’s paramount to emphasize that while Candexil Plus is an indispensable tool for blood pressure management, it does not constitute a cure for hypertension. Consistent use as directed by a healthcare professional is vital to sustain its benefits.

For a comprehensive understanding of the potential benefits and individual suitability, it is prudent to engage in a discussion with a healthcare provider. The list of benefits mentioned here represents the most prominent advantages, but individual experiences may vary.


Before embarking on a course of Candexil Plus, it’s crucial to consider several precautions.

Prior to Commencing Candexil Plus

  1. Pregnancy: Candexil Plus is not recommended for pregnant individuals. If there’s a possibility of pregnancy or plans to conceive, it’s essential to inform your healthcare provider.
  2. Allergies: If you have known allergies to any of the ingredients in Candexil Plus, including Candesartan and Hydrochlorothiazide, this medication should be avoided.
  3. Liver Impairment: In cases of severe liver impairment and/or cholestasis, the use of Candexil Plus is contraindicated.

During Treatment

During the course of Candexil Plus treatment, several crucial considerations should be kept in mind:

  • Dosage Timing: Candexil Plus is typically taken once daily, with or without food.
  • Hydration: Increasing fluid intake while on Candexil Plus is recommended.
  • Urinary Changes: It’s important to be aware that it may initially increase the frequency of urination.

Special Considerations

Certain populations require specialized attention:

  • Children: The safety and efficacy of Candexil Plus have not been established in children.
  • Elderly Patients: In most cases, dosage adjustments are not required for the elderly.
  • Renal Impairment: Patients with renal impairment must have their creatinine clearance evaluated, with dosage adjustments if needed. Severe renal impairment is a contraindication for Candexil Plus.
  • Hepatic Impairment: For individuals with mild to moderate liver impairment, dosage adjustments may be necessary. However, severe hepatic impairment and/or cholestasis constitute contraindications for it.


To maintain the integrity of Candexil Plus, it should be stored at 77 degrees Fahrenheit (25 degrees Celsius). Brief storage at temperatures between 59 and 86 degrees Fahrenheit (15 and 30 degrees Celsius) is permissible. It’s crucial to keep this medication away from heat, moisture, and direct light. The bathroom is not an appropriate storage location, and it should be kept out of the reach of children and pets.

For a comprehensive grasp of storage instructions and any additional details, it’s prudent to consult a healthcare professional. Always seek professional guidance before commencing any new medication.

Key Information:

Attribute Details
Manufacturer DEVA Holding
Available Dosages 16 mg/12.5 mg and 32 mg/12.5 mg
Recommended Dosage One tablet once daily
Primary Active Ingredients Kandesartan sileksetil (16 mg) and Hidroklorotiyazid (12.5 mg)
Prominent Applications Hypertension Management


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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