Description
Usage and Administration
Berinin P I.V. Injection is administered intravenously. With proper training, patients or caregivers can perform the infusion at the first sign of an attack. Proper understanding of the injection technique and safe disposal of needles and other items used during the process is essential.
Medical Indications
Berinin P I.V. Injection is indicated for individuals with hereditary angioedema, a condition characterized by insufficient levels of a specific protein that leads to swelling attacks and associated symptoms such as stomach problems or respiratory difficulties.
Precautions and Warnings
Patients should avoid using Berinin P I.V. Injection if they have previously experienced a life-threatening allergic reaction to complement C1 esterase inhibitor. It is important to inform the doctor about any history of stroke or blood clot before starting the treatment. During infusion, patients must seek emergency medical help if they experience signs of an allergic reaction, such as hives, wheezing, difficulty breathing, or swelling of the face and throat.
Side Effects
Berinin P I.V. Injection can cause side effects, though not everyone will experience them. It is important to be aware of potential side effects and seek medical attention if they occur.
| Type of Side Effect | Description |
|---|---|
| Allergic Reactions | Hives, chest tightness, fast heartbeats, light-headedness, wheezing, difficulty breathing, etc. |
| Serious Side Effects | Numbness or weakness, chest pain, confusion, pain or swelling, vision, speech, or balance issues. |
| Other Considerations | Risk of disease transmission from human plasma despite thorough testing and treatment. |
Hereditary Angioedema: An Overview
Hereditary angioedema (HAE) is a rare genetic condition causing severe swelling, often affecting the face, hands, feet, and genitals. It can also impact the gastrointestinal tract and airways, posing life-threatening risks.
Causes
HAE is caused by an imbalance of a certain protein in the body, often due to a genetic defect affecting the production or function of C1 inhibitor.
Symptoms
Swelling is the primary symptom of HAE, with episodes lasting 2 to 5 days. Swelling in the throat is particularly dangerous, while swelling in the feet, hands, or abdomen can cause pain and impair daily activities.
Triggers
Common triggers for HAE include stress, minor injuries, illnesses, physical activities, and certain medications.
Treatment
Treatment for HAE focuses on managing symptoms and reducing the frequency of attacks. Advances in treatment have significantly improved the quality of life for individuals with HAE.
Benefits of Berinin P I.V. Injection
| Benefit | Description |
|---|---|
| Treatment of HAE | Effective in treating and preventing attacks of hereditary angioedema. |
| Rapid Delivery | Intravenous administration allows for quick and efficient delivery during acute HAE attacks. |
| Prevention of Attacks | Regular use helps prevent future attacks, improving quality of life for individuals with HAE. |
Dosage for Hereditary Angioedema (HAE)
Berinin P I.V. Injection is used to treat acute abdominal, facial, or laryngeal attacks of HAE in adults and children. It is used on demand, administered intravenously at a recommended dosage of 20 International Units (IU) per kilogram of body weight. Doses lower than 20 IU/kg should not be administered.
Administration
The injection is given by intravenous infusion as soon as possible during an acute HAE attack. It can be administered by a healthcare professional or self-administered with proper training.
Self-Administration
Patients or caregivers can be trained to self-administer Berinin P I.V. Injection, particularly important during life-threatening laryngeal HAE attacks. Immediate medical attention is advised following self-administration.
Storing and Handling Berinin P I.V. Injection
| Aspect | Instructions |
|---|---|
| Storage | Store in a safe place away from direct sunlight and heat, following manufacturer’s instructions. Keep out of reach of children and pets. |
| Handling | Assemble all supplies, wash hands thoroughly, draw up the medication in a syringe, find a suitable injection site, and inject at a slanted angle into a vein. Follow safe disposal practices for needles and other used items. |
Conclusion
Berinin P I.V. Injection is a crucial treatment for individuals with hereditary angioedema, offering rapid relief from acute attacks and preventing future episodes. Proper administration and adherence to precautions can significantly improve the quality of life for patients. Always consult with a healthcare provider for personalized medical advice and follow their instructions carefully.
Muhammad nasir –
patient
Medical Guidance Center –
Hello Muhammad, this is Wikikenko.
Thank you for your comment. I apologize, but I did not fully understand your request. Could you please provide some additional context around the patient you mentioned? As a pharmaceutical encyclopedia, our goal is to answer any specific questions you may have to the best of our abilities. Some details that could help with responding include:
What is the patient’s condition or symptoms?
Are you inquiring about potential drug interactions, recommended dosages or treatment options for a certain diagnosis?
Did the patient have any other questions come up during a consultation?
Please feel free to share more details so I can try to address your concern as thoroughly as possible. Your feedback helps us continuously improve our resources. I’m happy to continue our discussion further once I have a better understanding of the patient scenario.