Navelbine Soft Capsule 30 Mg

Navelbine Soft Capsule 30 Mg is a medication used in the treatment of various types of cancer. In this comprehensive article, we will delve into its composition, indications, dosage, safety, and potential side effects, providing medical professionals with a thorough understanding of this important oncology drug.

Dosage form

Pack size

Potency

30 Mg

Manufacturer

Origin

Generic Name (Ingredient)

Vinorelbin Tartrate 41.55 Mg (Equivalent To 30 Mg Vinorelbine Base)

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Description

Active Ingredient and Pharmaceutical Form

The primary active substance in Navelbine is Vinorelbine Tartrate, a semi-synthetic vinca alkaloid derivative. Navelbine is available in the form of soft gelatin capsules.

Navelbine Soft Capsule 30 Mg Indications

Navelbine is prescribed for the following oncological conditions:

Advanced Breast Cancer

Navelbine is used as a single agent or in combination therapy after the failure of standard treatment options.

Advanced Non-Small Cell Lung Cancer

Navelbine is administered as a single agent or in combination as a first-line treatment.

Dosage and Administration

The recommended dosage of Navelbine is 30 mg/m² administered intravenously over 6 to 10 minutes once a week. Dosage modifications may be necessary based on individual patient response and myelosuppression.

Safety and Effectiveness

Navelbine has demonstrated efficacy in the treatment of the specified cancers. Regular monitoring and appropriate dose adjustments are crucial to manage potential side effects.

Side Effects

The common side effects associated with Navelbine include:

Myelosuppression

Dose hold or reduction may be necessary in case of severe myelosuppression.

Other Side Effects

Fatigue, nausea, and neuropathy may also occur.

Drug Interactions

Navelbine (Vinorelbine Tartrate) has a significant number of known drug interactions, including 70 major, 380 moderate, and 17 minor interactions. Common interacting medications include Abraxane, Advair HFA, Afinitor, Cymbalta, Lyrica, Plavix, and Zofran, among others.

Storage and Handling

Navelbine capsules should be stored at a temperature between 5°C to 30°C (41°F to 86°F), protected from excessive light exposure, and kept in their original packaging. Diluted Navelbine solutions may be used for up to 24 hours under normal room light when stored in polyvinyl chloride bags at the recommended temperature range.

Dietary Considerations

Patients taking Navelbine should be monitored for potential issues such as constipation, bowel obstruction, extravasation, neurologic toxicity, pulmonary toxicity, and embryo-fetal toxicity. Appropriate dietary modifications, such as increased fiber intake, hydration, and the use of stool softeners, may be necessary to mitigate these concerns.

Conclusion

In conclusion, Navelbine Soft Capsule 30 Mg is a valuable medication in the management of advanced breast cancer and non-small cell lung cancer. By understanding its composition, indications, dosage, safety, and potential interactions, healthcare professionals can ensure the safe and effective use of this oncology drug for their patients.

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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.

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