Description
Navelbine Soft Capsule 20 Mg is a medication that contains the active ingredient vinorelbine. Formulated as soft capsules, each one contains 20 mg of vinorelbine tartrate, along with 38.44 mg of sorbitol as an excipient.
Active Ingredient
The primary active ingredient in Navelbine Soft Capsule 20 Mg is vinorelbine, a vinca alkaloid that exerts its therapeutic effects through a well-defined mechanism of action.
Pharmaceutical Form
Navelbine is available in the form of soft capsules, providing a convenient and patient-friendly delivery method.
Navelbine Soft Capsule 20 Mg has been approved for the treatment of several types of cancer, including:
Advanced Breast Cancer
Navelbine is indicated for the treatment of advanced breast cancer after the failure of standard therapy. It can be used as a single agent or in combination with other cancer treatments.
Advanced Non-Small Cell Lung Cancer
Navelbine serves as a first-line treatment, either as a single agent or in combination, for advanced non-small cell lung cancer.
Completely Resected Non-Small Cell Lung Cancer
In patients with completely resected non-small cell lung cancer of stage IB or greater, Navelbine, in combination with cisplatin, is recommended.
Administration and Storage
Navelbine Soft Capsule 20 Mg is administered intravenously through a needle or catheter inserted into a vein. It is essential to store the medication at a temperature of 2 to 8 degrees Celsius and protect it from light exposure. The shelf life of Navelbine is 3 years.
Visual Appearance and Prescription Status
Navelbine Soft Capsule 20 Mg appears as a clear, colorless to pale yellow solution. It is classified as a Schedule 4: Prescription Only Medicine, requiring a prescription from a healthcare provider.
Contraindications and Precautions
Navelbine Soft Capsule 20 Mg should not be used in the following situations:
Allergy
If you have an allergy to vinorelbine or any of its components, you should not use this medication.
Severe Low White Blood Cell Counts
Individuals with severely low white blood cell counts are contraindicated from using Navelbine.
Liver Disease
Caution is advised for those with liver disease when using Navelbine.
Bone Marrow Suppression
If you have a history of bone marrow suppression, consult your healthcare provider before starting Navelbine.
Nerve Disorders
Inform your doctor if you have a pre-existing nerve disorder, as this may impact the suitability of Navelbine.
Pregnancy
Navelbine can harm an unborn baby or cause birth defects. Women may need a negative pregnancy test before starting treatment, and both men and women must use effective birth control during treatment and for a specified period after the last dose.
Side Effects
Navelbine Soft Capsule 20 Mg can cause a range of side effects, including:
- Nausea
- Fatigue
- Hair loss
- Bone marrow suppression
- Neuropathy
If you experience any side effects, it is crucial to report them to your doctor or directly to the Therapeutic Goods Administration (TGA) Reporting Problems.
Dosage and Administration
The recommended dosage of Navelbine Soft Capsule 20 Mg varies depending on the specific indication and whether it is used as a single agent or in combination with other drugs. Your healthcare provider will determine the appropriate dosage and administration schedule based on your individual needs.
Storage and Handling
When handling Navelbine Soft Capsule 20 Mg, it is essential to follow proper storage and handling procedures. Store the medication at a temperature of 2 to 8 degrees Celsius, protect it from light exposure, and dispose of any unused or expired Navelbine properly according to local regulations.
Conclusion
Navelbine Soft Capsule 20 Mg is a valuable tool in the fight against certain types of cancer. By understanding its indications, administration, contraindications, and potential side effects, healthcare providers can make informed decisions and provide the best possible care for their patients. As a medical journalist, I hope this comprehensive overview has shed light on the therapeutic potential of this important pharmaceutical solution.
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