Description
Pandev is a medication that comes in the form of enteric-coated tablets. Each tablet packs a potent 40 mg of the active ingredient, pantoprazole (as sodium sesquihydrate). Pantoprazole belongs to the group of drugs known as “proton pump inhibitors,” and its primary role is to reduce the excessive production of stomach acid.
Uses
Pandev plays a pivotal role in the treatment of various stomach and intestinal conditions, including:
Reflux Esophagitis
This condition is common among individuals aged 12 and above. Pandev is a trusted solution for managing reflux esophagitis, providing relief from acid-related discomfort.
Helicobacter pylori Eradication
When duodenal and gastric ulcers are caused by the presence of Helicobacter pylori (H.pylori) bacteria, Pandev is part of an effective treatment plan. It is used in conjunction with appropriate antibiotics to reduce the chances of recurrence.
Peptic Ulcers
Both duodenal and gastric ulcers can be effectively treated with Pandev, offering relief from the pain and discomfort associated with these conditions.
Moderate and Severe Esophageal Reflux
For individuals suffering from moderate to severe esophageal reflux, Pandev provides relief by reducing excess stomach acid.
Zollinger Ellison Syndrome and Pathological Hypersecretory Conditions
In cases of rare conditions like Zollinger Ellison Syndrome and other pathological hypersecretory conditions, Pandev can help manage excessive acid production.
Dosage
The recommended dosage of Pandev varies based on the specific condition being treated:
Gastroesophageal Reflux Disease (GERD)
- Adults and Children Over 12 Years: Typically, one Pandev 40 mg tablet per day is recommended. In some instances, the dose may be doubled to two tablets per day. For patients who do not show improvement after 4 weeks of treatment, an additional 4-week treatment can be considered.
Helicobacter pylori Eradication
For this purpose, Pandev is used in combination with suitable antibiotics. The recommended combinations for H.pylori eradication depend on resistance status:
Combination | Components |
---|---|
Twice daily | 1 Pandev 40 mg Enteric Coated Tablet, 1000 mg amoxicillin, and 500 mg clarithromycin |
Twice daily | 1 Pandev 40 mg Enteric Coated Tablet, 400-500 mg metronidazole (or 500 mg tinidazole), and 250-500 mg clarithromycin |
Twice daily | 1 Pandev 40 mg Enteric Coated Tablet, 1000 mg amoxicillin, and 500 mg metronidazole (or 500 mg tinidazole) |
The combination therapy for H.pylori eradication typically spans 7 days and may be extended for a total of up to 2 weeks.
Precautions
Before starting Pandev, it’s essential to consider the following:
- Allergies: Do not use Pandev if you are allergic to pantoprazole or any other ingredients in the medication. Additionally, avoid it if you have allergies to other proton pump inhibitors.
How is it Stored?
While specific storage instructions for Pandev may not be readily available, it is generally recommended to store medications in a cool, dry place away from direct sunlight. Always consult the package insert or your pharmacist for precise storage guidance.
Pandev Side Effects
As with any medication, Pandev may have varying side effects among individuals. Some of the most commonly reported adverse effects include:
- Headache
- Diarrhea
- Skin rashes
In some cases, these side effects have been severe enough to necessitate discontinuation of treatment. It’s important to note that individual responses to medications can differ, influenced by factors such as disease state, age, weight, gender, ethnicity, and overall health.
If you experience any side effects while taking this tablet, consult your healthcare provider. They can provide guidance tailored to your specific circumstances and health history.
Can I Take Pantoprazole with Other Medications?
Yes, pantoprazole, the active ingredient in Pandev, can be taken alongside other medications. However, it’s essential to be aware of potential interactions, including drugs such as antiretroviral medications, warfarin, and methotrexate. These interactions can affect the effectiveness of both pantoprazole and the other medications.
There are a total of 163 known drug interactions with pantoprazole, including 4 disease interactions. Among these, 16 are major, 128 are moderate, and 19 are minor interactions. Always consult with a healthcare professional before starting or discontinuing any medication to ensure your safety and treatment efficacy.
How Does it Work?
Pantoprazole, the active ingredient in Pandev, operates by irreversibly blocking the actions of an enzyme called H+/K+ ATPase, also known as the gastric proton pump. This proton pump resides in the parietal cells of the stomach wall. By blocking this enzyme, pantoprazole effectively reduces the production of stomach acid, which allows damaged tissue in the esophagus, stomach, and duodenum to heal. Pantoprazole belongs to a class of medicines known as proton pump inhibitors (PPIs).
Conclusion
Pandev Enterik Coated Tablet 40 Mg is a valuable medication for managing a range of stomach and intestinal conditions. Whether it’s addressing reflux esophagitis, eradicating H.pylori, or managing peptic ulcers, this tablet plays a pivotal role in enhancing the well-being of individuals.
However, it’s crucial to consider allergies, potential side effects, and interactions with other medications before use. Consultation with a healthcare professional is highly recommended to ensure safe and effective treatment. This information is intended for general informational purposes and should not replace professional medical advice. Always consult with a healthcare professional for all health-related questions and decisions.
For a more professional appearance, here’s a table summarizing essential information about this tablet:
Name | Pandev Enterik Coated Tablet 40 Mg |
---|---|
Active Ingredient | Pantoprazole (as sodium sesquihydrate) |
Primary Use | Treatment of various stomach and intestinal conditions |
Recommended Dosage | Varies by condition (consult healthcare provider) |
Storage | Cool, dry place, away from direct sunlight |
Availability | Pharmacies, blister packs (14 or 28 tablets) |
Price (As of September 2023) | Approximately 70.54 Turkish Lira |
Side Effects | Headache, diarrhea, skin rashes (individual responses may vary) |
Interactions | Numerous potential interactions, including antiretroviral drugs, warfarin, and methotrexate |
Mechanism of Action | Irreversible blocking of the gastric proton pump, reducing stomach acid production |
Important Note | Consult a healthcare professional before use for personalized guidance |
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