Blemisin Liyofilize Powder Iceren Vial 30 Mg

“Blemisin Liyofilize Powder Iceren Vial 30 Mg” houses the potent Bleomycin Sulfate as its active ingredient, a cytotoxic glycopeptide antibiotic derived from Streptomyces verticillus. Widely incorporated into chemotherapy regimens, this medication showcases efficacy in diverse cancer treatments.

Dosage form

Pack size


30 Mg



Generic Name (Ingredient)

Bleomycin Sulfate 30 Mg [30, 000 (30X103) Equivalent To Iu]

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Blemisin Liyofilize Powder Iceren Vial 30 Mg Mechanism of Action

The precise mechanism of bleomycin’s action remains elusive, yet prevailing evidence suggests its primary role in inhibiting DNA synthesis, with secondary effects on RNA and protein synthesis. The induction of single and double-stranded breaks in DNA further characterizes its impact.

Clinical Use

Bleomycin features prominently in various treatment protocols, including the ABVD regimen (Doxorubicin, Bleomycin, Vinblastin, Dacarbazin) administered intravenously. Additionally, it finds application in addressing lymphatic malformations and giant liver hemangiomas.

Administration and Dosage

Provided as a sterile lyophilized powder, Bleomycin for injection, USP, offers 15 units per vial for intramuscular, intravenous, subcutaneous, or intrapleural administration.

Side Effects

Pulmonary fibrosis stands out as the most severe side effect associated with bleomycin, with higher occurrences in elderly patients and those receiving doses exceeding 400 units. Other adverse effects encompass mucocutaneous manifestations such as rash, erythema, hyperpigmentation, urticaria, febrile reactions, and mucositis.


Cancer Treatment: Bleomycin proves effective in treating various cancers, including Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, testicular cancer, and cervical cancer.

Part of Chemotherapy Regimens: Integral to chemotherapy, it features in protocols like ABVD, administered intravenously.

Treatment of Other Conditions: Beyond cancer, Bleomycin addresses lymphatic malformations and giant liver hemangiomas.

However, caution is paramount, and the supervision of a qualified physician experienced in cancer chemotherapeutic agents is imperative, given potential side effects, notably pulmonary fibrosis.


Medical Supervision: Usage should be under the watchful eye of a qualified physician experienced in cancer chemotherapeutic agents.

Pulmonary Toxicity: Elevated risk in elderly patients or doses exceeding 400 units, but vigilance is necessary even in younger patients and with lower doses.

Other Side Effects: Mucocutaneous reactions, febrile responses, and mucositis underscore potential adverse effects.

Allergies: Patients must disclose known allergies to avert possible allergic reactions.

Other Medications: Informing healthcare providers about concurrent medications is crucial to prevent potential drug interactions.

For more comprehensive information, consultation with a healthcare provider is advised, as this list may not encompass all conceivable precautions.

Blemisin Liyofilize Powder Iceren Vial 30 Mg Interactions

Brentuximab Vedotin: Contraindicated due to an escalated risk of pulmonary toxicity.

Adenovirus Types 4 and 7 Live, Oral: Bleomycin diminishes the effects of this medication through pharmacodynamic antagonism.

Etrasimod: Mutual potentiation of immunosuppressive effects heightens the risk of infection.

Influenza Virus Vaccine Quadrivalent, Adjuvanted: Bleomycin diminishes the effectiveness of this vaccine via pharmacodynamic antagonism.

For a more nuanced understanding, healthcare providers should be consulted, recognizing that this list may not encompass all conceivable interactions.


In conclusion, “Blemisin Liyofilize Powder Iceren Vial 30 Mg,” housing Bleomycin Sulfate, emerges as a potent ally in the intricate landscape of cancer treatment. Its manifold benefits are accompanied by a set of precautions and potential interactions, emphasizing the need for meticulous medical supervision. This nuanced approach ensures that the therapeutic potential of this medication is harnessed while minimizing the risks associated with its use.

Overview of “Blemisin Liyofilize Powder Iceren Vial 30 Mg”

Aspect Information
Active Ingredient Bleomycin Sulfate
Mechanism of Action Inhibition of DNA synthesis, with evidence of lesser inhibition of RNA and protein synthesis.
Clinical Use Cancer treatment (Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, testicular cancer, cervical cancer), ABVD regimen, treatment of lymphatic malformations, and giant liver hemangiomas.
Administration and Dosage Sterile lyophilized powder for reconstitution, 15 units per vial, for intramuscular, intravenous, subcutaneous, or intrapleural administration.
Side Effects Pulmonary fibrosis (most severe), mucocutaneous toxicity (rash, erythema, hyperpigmentation, urticaria), febrile reactions, mucositis.
Precautions Medical supervision, vigilance for pulmonary toxicity, awareness of other side effects, disclosure of allergies, and information on concurrent medications.
Interactions Contraindication with Brentuximab Vedotin, pharmacodynamic antagonism with Adenovirus Types 4 and 7 Live, Oral, mutual potentiation with Etrasimod, and pharmacodynamic antagonism with Influenza Virus Vaccine Quadrivalent, Adjuvanted.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

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