Precort-Liyo I.M./I.V. Injection Icin Liyofilize Powder Iceren Amp. 40 Mg

In the realm of medical therapeutics, Precort-Liyo emerges as a potent ally in the form of a lyophilized powder designed for intramuscular (I.M.) or intravenous (I.V.) injection. This comprehensive guide explores the essential aspects of Precort-Liyo, including its composition, therapeutic indications, usage guidelines, potential side effects, precautions, and its relevance in the context of COVID-19…

Dosage form

Pack size


40 Mg



Generic Name (Ingredient)

Each Ampoule Contains 53.03 Mg Methylprednisolone Sodium Succinate Equivalent To 40 Mg Methylprednisolone. Solvent Bulb; Contains 2 Ml Of Water For Injection.

Assuming your emergency circumstances for this product, visit Urgent Quotation page. Besides, for any pharmaceutical questions, please ask us in the comments section.


Each ampoule of Precort-Liyo houses 40 mg of methylprednisolone, equivalent to 53.038 mg of methylprednisolone sodium succinate. The formulation also includes specific excipients such as dibasic sodium phosphate heptahydrate, monobasic sodium phosphate anhydrous, sodium chloride, and lactose monohydrate. This precise blend ensures both efficacy and safety.

Precort-Liyo presents itself in the form of a lyophilized powder, appearing as a white, lyophilized cake. This particular form is well-suited for intramuscular and intravenous administration, offering convenience and rapid action when needed.


Precort-Liyo’s therapeutic spectrum is vast, making it an invaluable tool for various medical conditions. It is indicated for the treatment of:

Endocrine Diseases: Including primary and secondary adrenal insufficiency, acute adrenocortical insufficiency, congenital adrenal hyperplasia, and more.

Rheumatic Diseases: Covering acute gout arthritis, acute rheumatic carditis, ankylosing spondylitis, and other related conditions.

Skin Diseases: Such as autoimmune bullous diseases, drug reactions like erythema multiforme, and systemic lupus erythematosus.

Allergic Reactions: To control severe or disabling allergic conditions that do not respond to traditional treatments.

Eye Diseases: Addressing severe, acute, or chronic allergic or inflammatory eye disorders.

Gastrointestinal Diseases: Including ulcerative colitis and regional enteritis, when systemic therapy is required.

Respiratory System Diseases: For conditions like symptomatic sarcoidosis, berylliosis, and more.

Hematological Diseases: Precort-Liyo is indicated for both non-malignant and malignant hematological conditions, providing a versatile option for patients.

Usage Guidelines

Precort-Liyo is typically administered via intramuscular or intravenous injection. Before use, it is imperative to carefully read and follow the usage instructions provided. Should any questions arise regarding the prescription’s purpose, it’s advisable to consult with a medical professional for clarity.


While the exact storage conditions for Precort-Liyo may not be specified in the available resources, it is generally recommended to adhere to the storage instructions provided by the manufacturer or healthcare provider. This ensures the preservation of its potency and safety for usage.

Side Effects

Like all medicines, Precort-Liyo may induce side effects, although not everyone may experience them. These can be categorized into minor and serious side effects.

Minor Side Effects May Include:

  • Abnormal fat deposits on the face, neck, and trunk.
  • Acne.
  • Dry scalp.
  • Lightening of normal skin color.
  • Red face.
  • Reddish purple lines on the arms, face, legs, trunk, or groin.
  • Swelling of the stomach area.
  • Thinning of the scalp hair.

Serious Side Effects Can Involve:

  • Hives.
  • Difficulty breathing.
  • Swelling of your face, lips, tongue, or throat.
  • Blurred vision, tunnel vision, eye pain, or seeing halos around lights.


Precautions should also be observed. Grapefruit and grapefruit juice may interact with Precort-Liyo, leading to unwanted side effects, so their use should be avoided. Moreover, the administration of “live” vaccines while using Precort-Liyo is not recommended.

Duration of Usage

The duration of Precort-Liyo’s usage is condition-specific and influenced by the patient’s response to the medication. General guidelines for various conditions are as follows:

  • For rheumatic diseases, intravenous (IV) use is indicated at a dose of 1g/day for 1, 2, 3, or 4 days.
  • In cases of systemic lupus erythematosus, IV usage at a dose of 1g/day for 3 days is recommended.
  • Multiple sclerosis treatment may involve IV usage at a dose of 1g/day for 3 or 5 days.
  • Glomerulonephritis, lupus nephritis, and other edematous conditions may necessitate IV usage at a dose of 30mg/kg for 4 days or 1g/day for 3, 5, or 7 days.

These are general guidelines, and the precise duration and dosage should be determined by a healthcare provider. Always consult with a doctor or pharmacist before initiating any new medication.

The Role of Precort-Liyo in COVID-19 Treatment

While corticosteroids, including methylprednisolone found in Precort-Liyo, have been employed in the treatment of COVID-19 to mitigate lung inflammation, it’s essential to emphasize that Precort-Liyo is not explicitly indicated for COVID-19 treatment. The application of corticosteroids varies across different conditions, including allergies, arthritis, asthma, and more. Their use for COVID-19 or any other serious health condition should always be guided by a healthcare provider.


In the intricate landscape of medical therapeutics, Precort-Liyo shines as a versatile and potent tool. Its composition, therapeutic indications, usage guidelines, potential side effects, and precautions are integral to its effective and safe application. As with any medication, adherence to healthcare provider recommendations is the key to optimizing outcomes.

Disclaimer: This article provides general information and does not replace professional medical advice. Always consult with a healthcare provider for personalized guidance on medication usage.

Table: Key Information on Precort-Liyo
Composition Methylprednisolone (40 mg) equivalent to Methylprednisolone Sodium Succinate (53.038 mg) with excipients
Pharmaceutical Form Lyophilized powder for injection in ampoules
Therapeutic Indications Broad spectrum, including endocrine, rheumatic, skin, allergic, eye, gastrointestinal, respiratory, and hematological diseases
Usage Guidelines Intramuscular or intravenous injection
Storage Recommendations As per manufacturer or healthcare provider instructions
Potential Side Effects and Precautions Range of side effects (minor and serious), precautions regarding grapefruit interaction and “live” vaccines
Duration of Usage Condition-specific, determined by a healthcare provider


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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