Metalcaptase Tablet 300 Mg

Description

Metalcaptase is a medication available in two strengths: 150 mg and 300 mg, with Penicillamine as its active ingredient. This versatile drug finds its utility in treating a spectrum of medical conditions.

Indications for Metalcaptase

Metalcaptase is indicated for the treatment of several conditions, including:

1. Morbus Wilson

Morbus Wilson, a rare inherited disorder, leads to the accumulation of copper in vital organs such as the liver and brain. Metalcaptase effectively addresses this condition.

2. Heavy Metal Poisoning

This medication forms complexes with heavy metals, particularly copper, aiding in their elimination through the kidneys.

3. Rheumatoid Arthritis

Metalcaptase finds application in the treatment of rheumatoid arthritis, offering relief to those afflicted by this autoimmune condition.

4. Cystinuria

Cystinuria is characterized by elevated levels of the amino acid cystine in urine, often resulting in the formation of cystine stones. Metalcaptase becomes a valuable option when other preventive methods prove insufficient or in cases of advanced cysteine stone disorders.

Dosage and Administration

The dosage of Metalcaptase varies depending on the condition being treated:

For Rheumatoid Arthritis

Patients typically initiate treatment with 150 mg of penicillamine daily for the first two weeks. The dosage then gradually increases to a maximum of 900 mg per day, with temporary increments to 1,200 mg, if necessary.

For Wilson’s Disease

The recommended daily dosage ranges from 10 to 20 mg of penicillamine per kilogram of body weight.

For Heavy Metal Poisoning

An initial daily dose of 4 x 300 mg penicillamine is advised, with the daily dosage not exceeding 40 mg of penicillamine per kilogram of body weight in prolonged treatments.

For Cystinuria

Patients typically take four daily doses of 225 to 525 mg penicillamine, depending on cysteine excretion.

It is essential to consume this medication on an empty stomach or one hour before meals, or two to three hours after meals, with an ample amount of fluids.

Availability and Pricing

In Turkey, Metalcaptase (YDI) Tablet 300 mg is available in packages containing 100 tablets. As of August 25, 2023, the retail price stood at 53.33 EUR. However, pricing may vary by region and over time.

Contraindications

Metalcaptase should not be administered to patients who have displayed hypersensitivity to it. Hypersensitivity reactions may manifest as hives, rash, swollen glands, breathing difficulties, and swelling of the face, lips, tongue, or throat.

Side Effects

Metalcaptase is associated with a high incidence of side effects, some of which can be severe. Consequently, patients undergoing Metalcaptase therapy must remain under close medical supervision throughout the treatment period. Common side effects include:

• Decreased sense of taste
• Skin changes such as wrinkling or pimples
• Stomach discomfort, nausea, vomiting, diarrhea, loss of appetite
• Numbness or a tingling sensation
• Ringing in the ears
• Non-healing wounds

More serious side effects may include:

• New or worsening joint pain
• Muscle weakness in limbs and face
• Respiratory issues
• Mouth ulcers and skin abnormalities
• Pain or burning during urination and swelling

This list is not exhaustive, and patients should promptly consult their healthcare provider if they experience any adverse effects.

Precautions

Due to the high incidence of untoward reactions associated with Metalcaptase, patients undergoing this therapy should remain under rigorous medical supervision throughout the treatment. Any alterations in medication should be conducted under the guidance of a healthcare professional.

Exploring Alternatives

For patients who exhibit intolerance to Metalcaptase therapy, an alternative treatment option is trientine hydrochloride. This chelating agent serves as a second-line treatment for Wilson’s disease, a genetic disorder characterized by copper buildup in the body. It is vital to emphasize that any modifications in medication should be executed under the vigilant supervision of a healthcare provider.

In conclusion, this comprehensive guide has unveiled Metalcaptase Tablet 300 mg, providing essential insights into its composition, applications, and precautions. Armed with this knowledge, individuals and healthcare professionals can make informed decisions regarding its use. However, it is paramount to consult a healthcare provider for personalized medical advice tailored to specific health conditions.

Overview

This guide serves as a valuable resource for understanding Metalcaptase Tablet 300 mg, ensuring informed decision-making and safe medication use. Always consult a healthcare professional for personalized medical advice