Merpurin Tablet

Merpurin, a medication containing the active ingredient mercaptopurine, is a vital tool in the fight against specific types of leukemia. In this detailed guide, we unravel the essential aspects, from its uses to precautions and dosage. Let’s navigate the world of this pharmaceutical to understand it better.

Dosage form

Pack size


50 Mg



Generic Name (Ingredient)

Mercaptopurine 50 Mg

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The Medication Profile: Merpurin is available in the form of a 50 mg tablet. These tablets are characterized by their light yellow color, round shape, biconvex design, and a notch in the middle on one side. They are packaged in amber-colored glass bottles with child safety caps made of polypropylene, each containing 25 tablets.

The Purpose

A Cytotoxic Ally: Merpurin belongs to a class of drugs known as cytotoxics. It is primarily employed in the treatment of leukemia. Its mechanism of action revolves around reducing the production of new blood cells by the body.

Conditions Treated by Merpurin

Merpurin tablets are effectively used to treat the following conditions:

1. Acute Myeloid Leukemia (AML)

  • AML is a rapidly progressing disease characterized by a reduction in the number of white blood cells produced by the bone marrow. This can lead to abnormal fatigue, an increased risk of infection, and symptoms like bruising and bleeding.

2. Acute Lymphoblastic Leukemia (ALL)

  • ALL, another swiftly advancing disease, results in an excessive production of a specific type of white blood cell called lymphoblasts. These abnormal cells interfere with the function of crucial cells in the body, compromising the body’s ability to fight infections and leading to symptoms like bruising and bleeding.


Oral Administration: Merpurin is administered orally. It is imperative to thoroughly read and understand the medication’s instructions before usage, as they contain vital information. These instructions should be retained for future reference. If there are any uncertainties, it is advisable to consult a healthcare provider. Merpurin is prescribed exclusively for the individual and should not be shared.

In the event of a doctor or hospital visit during Merpurin treatment, it is essential to inform the attending healthcare professional about the medication. Adherence to the prescribed dosage is crucial; using a higher or lower dose than recommended is not advisable.

Precautions and Considerations

Allergic Reactions: Merpurin should not be used if there is a known allergy to 6-mercaptopurine or any other components present in Merpurin. Consultation with a healthcare provider or pharmacist is recommended for clarification if any uncertainty exists.

Vaccinations: If vaccination is necessary, especially after recent treatment, caution must be exercised. it recipients should avoid live vaccines (e.g., flu vaccine, measles vaccine, BCG vaccine, etc.) until deemed safe by their healthcare provider. This precaution is essential as some vaccines can pose infection risks when administered alongside Merpurin.

 Side Effects

Some common side effects associated with Merpurin include:

  • Hyperuricemia
  • Bone marrow toxicity
  • Hypoplasia
  • Anorexia
  • Diarrhea
  • Leukopenia
  • Thrombocytopenia
  • Intestinal ulceration
  • Crystalluria with hematuria
  • Immunosuppression
  • Interstitial pneumonitis
  • Cutaneous hyperpigmentation
  • Alopecia

It is important to note that not everyone will experience these side effects, and their severity and duration may vary from person to person. In case of any side effects while taking Merpurin, it is advisable to consult with a healthcare provider or pharmacist for guidance on managing them.


Personalized Treatment: The dosage of Merpurin varies according to the individual and the specific condition being treated. Precise adherence to the doctor’s instructions is crucial. Typically, the starting dose for adults and children is 2.5 mg per kilogram of body weight per day. However, adjustments may be made based on individual responses and any encountered side effects. Consistency in the timing administration is important to maintain a steady medication level in the body.

Duration of Treatment

Customized Regimens: The duration of Merpurin treatment is tailored to each individual’s needs and the condition under treatment. It is paramount to follow the doctor’s directives meticulously and continue the medication for the prescribed duration, even if symptoms improve before completion. Any questions regarding the duration treatment should be directed to a healthcare provider.


In conclusion, Merpurin, with its active ingredient mercaptopurine, plays a crucial role in combatting leukemia, including AML and ALL. While offering valuable therapeutic benefits, it is vital to adhere to usage guidelines and precautions. Understanding the personalized dosage, duration of treatment, and potential side effects empowers individuals in their journey towards better health. Merpurin stands as a testament to medical advancements in the fight against leukemia.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


The truth is that when we’re sick, or worried about getting sick, the internet won’t help.

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If diagnoses could be made simply from a textbook or an article on a website, we would all be doctors and treat ourselves. Nothing can replace the experience and knowledge of specially trained people. As in any field, in medicine there are unscrupulous specialists, differences of opinion, inaccurate diagnoses and incorrect test results.


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