Evin I.M. Injection Icin Solution Iceren Ampul

Evin I.M. Injection, encapsulating the therapeutic prowess of dl-alpha tocopherol acetate, stands as a medical elixir in the realm of Vitamin E supplementation. This fat-soluble vitamin, a crucial constituent of this medication, is harnessed to address Vitamin E deficiency and related conditions. Available in the form of a clear, oily solution housed within amber-hued ampoules,…

Dosage form

Pack size


300 Iu/2Ml 5X2Ml



Generic Name (Ingredient)

Dl-Alpha Tocopherol Acetate 300

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Evin I.M. Injection finds its therapeutic purpose in the amelioration of conditions tethered to Vitamin E deficiency and insufficiency. In a healthcare landscape marked by diverse nutritional needs, this medication serves as a vital resource for restoring the body’s Vitamin E equilibrium.


The administration of Evin I.M. Injection demands precision and adherence to specific guidelines. Intricacies pertaining to its usage encompass:

  • Intramuscular Precision: Evin I.M. Injection is exclusively intended for deep intramuscular injection. It should never be introduced subcutaneously or intravenously. This emphatic directive underscores the importance of precise delivery to harness its therapeutic benefits.


The dosage of Evin I.M. Injection aligns with the distinctive needs of patients, encompassing both supplementation and prophylactic usage. Key dosage recommendations encompass:

  • Malabsorption Syndromes: For individuals grappling with malabsorption syndromes, the prescribed dosage stands at half an ampoule per day, meticulously administered intramuscularly. This measured approach ensures an effective response to Vitamin E replenishment.
  • Premature Babies and Vitamin E Deficiency: In the context of premature infants facing Vitamin E deficiency, the recommended dosage ranges from 50-100 mg/kg body weight per day. Administered via intramuscular injection, this tailored approach addresses the unique requirements of this patient cohort.

Evin I.M. Injection Precautions

The administration of Evin I.M. Injection necessitates vigilance and consideration of special precautions to ensure patient well-being:

  • Hepatic and Renal Vigilance: Patients with pre-existing liver or kidney dysfunction should approach the usage of this medication with caution. Monitoring and expert guidance are pivotal to navigate potential complexities.
  • Hypersensitivity and Iron Deficiency: Contraindications encompass known hypersensitivity to any component of the medication and concurrent cases of iron deficiency. Vigilance in patient selection is paramount to circumvent adverse reactions.
  • Concurrent Therapies: Patients under oral anticoagulant or estrogen therapies may experience prolonged bleeding time when exposed to Vitamin E. Prudent assessment and monitoring are essential when this medication coincides with such therapies.

Side Effects and Interactions

The administration of Evin I.M. Injection may introduce side effects and interactions that merit consideration:

  • Thrombophlebitis: Patients subjected to tocopherol-based therapy have reported instances of thrombophlebitis, characterized by inflammation of the veins. Clinical vigilance is paramount to address this potential complication.
  • Hemorrhagic Stroke: Therapeutic utilization of Vitamin E has been associated with hemorrhagic stroke. An astute risk-benefit evaluation guides its administration in relevant cases.
  • Interaction with Oral Anticoagulants: Patients concurrently using oral anticoagulants may witness an enhanced hypoprothrombinemic response when exposed to high doses of Vitamin E. This interaction underscores the necessity for meticulous monitoring.
  • Medication Interference: Medications encompassing cholestyramine, cholestipol, and orlistat may influence the absorption of Vitamin E. The administration of antacids can precipitate bile acids, potentially diminishing the absorption of fat-soluble vitamins.
  • Impact on Vitamin A: High doses of Vitamin E may influence Vitamin A stores. This intersection necessitates comprehensive assessment within a therapeutic context.
  • Consideration in Cancer Treatment: The antioxidant properties of Vitamin E have raised concerns regarding potential interactions with certain chemotherapeutic agents. A judicious approach to administration aligns with holistic patient care.

A Spectrum of Vitamin E Forms

Patients navigating Vitamin E supplementation can explore a spectrum of alternatives, each characterized by unique attributes. Noteworthy alternatives encompass:

Supplement Characteristics
RRR-alpha-tocopherol (d-alpha-tocopherol) Naturally sourced Vitamin E
All rac-alpha-tocopherol (dl-alpha-tocopherol) Synthetic Vitamin E
Tocotrienols Related compounds with Vitamin E activity

These Vitamin E forms exhibit distinct biological activities, underpinning their therapeutic relevance. Differential potency and applicability underscore the necessity for healthcare professional guidance during selection.

Pregnancy Considerations

The utilization of dl-alpha tocopherol acetate, the core component of Evin I.M. Injection, during pregnancy necessitates cautious contemplation. Scientific insights underscore the intricacies:

  • Safety in Animal Studies: While animal studies have not signaled harm, the safety parameters of high doses remain unknown.
  • Natural vs. Synthetic: A discourse emerges, accentuating the transfer efficiency of natural (d-alpha tocopherol) versus synthetic (dl-alpha tocopherol) Vitamin E to the developing fetus. A dialogue with healthcare providers assumes paramount importance to navigate this aspect prudently.

The tenet remains immutable: personalized healthcare decisions during pregnancy warrant rigorous consultation with healthcare providers. Patient-specific health contexts steer recommendations, accentuating the pivotal role of healthcare guidance.

Vitamin E Deficiency: Symptoms and Signifiers

Vitamin E deficiency, though relatively rare, manifests an array of symptoms that beckon attention. These hallmark indicators encompass:

  • Muscle Weakness: The central nervous system’s ally, Vitamin E combats oxidative stress and safeguards against muscle weakness.
  • Coordination and Walking Challenges: Impaired Purkinje neurons can usher in coordination and ambulation difficulties.
  • Numbness and Tingling: Peripheral neuropathy, signified by numbness and tingling, mirrors nerve fiber impairment.
  • Vision Deterioration: Vision degradation, stemming from weakened light receptors and ocular cell damage, underlines Vitamin E’s ocular significance.
  • Immune System Implications: Evidence hints at potential immune system modulation, particularly in older adults.

The constellation of symptoms warrants healthcare provider evaluation and tailored intervention in the event of suspected Vitamin E deficiency.


In conclusion, Evin I.M. Injection emerges as a beacon in the therapeutic voyage for Vitamin E replenishment. Fortified by the potency of dl-alpha tocopherol acetate, this medication extends its protective mantle to address Vitamin E deficiency and its ramifications. While accessible alternatives enrich the therapeutic landscape, a healthcare provider’s discernment remains the compass guiding patient-centric decisions.

As the complexities of Vitamin E administration unfold, special precautions, side effect awareness, and pregnancy considerations steer the course of responsible healthcare. In the realm of Vitamin E, healthcare providers assume the role of custodians, ensuring that patient well-being remains paramount.

Vitamin E deficiency, though relatively uncommon, beckons vigilance, with its nuanced symptoms warranting timely diagnosis and tailored management. In this multifaceted landscape, the collective aim is to empower individuals with knowledge, fostering informed healthcare decisions, and orchestrating a harmonious balance between therapeutic potential and patient well-being.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

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