Duact Capsule

(1 customer review)

Duact Capsule is a pharmaceutical remedy aimed at alleviating the distressing symptoms of allergic rhinitis. It is crafted by the renowned Glaxo Smith Kline Pharmaceuticals.

Dosage form

Pack size





Generic Name (Ingredient)

One Capsule; Acrivastin 8 Mg Pseudoephedrine Hcl 60 Mg

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Each Duact capsule encapsulates the potency of 8 mg of Akrivastin and 60 mg of Pseudoephedrine Hydrochloride. Additionally, auxiliary substances such as lactose and sodium starch glycolate play a supporting role.


Duact is meticulously formulated to offer respite from the often vexing symptoms of allergic rhinitis.

Dosage and Administration

The recommended dosage for adults and adolescents aged 12 and above stands at one capsule per day. However, should the need arise, this dosage can be adjusted to three times a day, with administration conducted via the oral route.


Duact should be used with caution and withheld in several specific scenarios, including:

1. Hypersensitivity:

It is contraindicated in individuals who display hypersensitivity to Akrivastin, Pseudoephedrine, or Triprolidine (a structural analogue of Akrivastin).

2. Cardiovascular Concerns:

Individuals with severe hypertension or those grappling with diseases accompanied by tachycardia should exercise caution.

3. Cardiac Conditions:

Duact is contraindicated in individuals with severe coronary artery disease.

4. Monoamine Oxidase Inhibitors (MAOIs):

Patients who have used Monoamine Oxidase Inhibitors within the last 14 days should refrain from using Duact.

5. Pheochromocytoma:

Individuals diagnosed with pheochromocytoma should avoid Duact.

6. Age Limit:

Duact is not suitable for children under the age of 12.

7. Metabolic Disorders:

Patients with diabetes mellitus and hyperthyroidism should not use Duact.

8. Special Populations:

For individuals with renal insufficiency, liver insufficiency, or those in the age group of 60 and above, caution should be exercised due to an elevated risk of adverse reactions.

Side Effects

Just like any pharmaceutical agent, Duact Capsule can usher in side effects. While not everyone will experience these side effects, those who do may require medical attention. The spectrum of potential side effects includes:

Common Side Effects:

  • Dry mouth.
  • Headache.
  • Sleepiness or unusual drowsiness.
  • Mild burning or stinging.
  • Itching or a tingly sensation.

Less Common Side Effects:

  • Acid or sour stomach.
  • Belching.
  • Body aches or pain.
  • Congestion.
  • Cough.
  • Dryness or soreness of the throat.
  • Fever.
  • Heartburn.
  • Hoarseness.
  • Indigestion.
  • Lack or loss of strength.
  • Nausea.
  • Nervousness.
  • Runny nose.
  • Stomach discomfort, upset, or pain.
  • Tender, swollen glands in the neck.
  • Trouble sleeping.
  • Trouble swallowing.
  • Voice changes.

Serious Side Effects:

In certain instances, Duact can lead to severe side effects. If you encounter symptoms such as a fast heart rate, pounding heartbeats, or dizziness when changing positions, seek immediate medical attention.

It is important to note that this list may not encompass all possible side effects. For precise information, consulting a healthcare professional is paramount.


Duact should not be combined with other sympathomimetic drugs, which encompass decongestants, appetite suppressants, or amphetamine-like psychostimulants.

Onset of Action

The initiation of Duact’s therapeutic action is often accompanied by a reduction in symptoms like pain or fever. The anti-inflammatory effects, however, may necessitate patience, often extending over a week or more. Duact’s levels in the bloodstream typically reach their zenith after 1 to 2 hours. Nevertheless, it is crucial to acknowledge that individual experiences can vary significantly. For the most accurate information, consulting with a healthcare professional is recommended.

Elimination of Duact

The elimination half-life of a drug represents the time it takes for the concentration of the drug in the body to decrease by half. In cases where liver function is compromised, the half-life of Duact can be prolonged, reaching a range of 3.1-3.4 hours. Typically, it takes approximately five half-lives for a drug to be almost entirely eliminated from the system. Therefore, the elimination period for Duact can extend to about 15.5 to 17 hours. It is essential to note that individual variations based on factors like age, health status, and the presence of liver or kidney issues can influence this timeframe. Thus, consulting with a healthcare professional remains the best approach for personalized insights.

Duact Capsule Benefits

Duact Capsule, a nonsteroidal anti-inflammatory drug (NSAID), operates by mitigating the actions of hormones that provoke inflammation and pain in the body. Its versatile utility extends to the treatment of various conditions, including:

1. Rheumatoid Arthritis, Ankylosing Spondylitis, and Osteoarthritis:

Duact finds its place in managing the signs and symptoms of these conditions.

2. Non-Articular Rheumatic Conditions:

These encompass afflictions such as frozen shoulder, bursitis, tendinitis, tenosynovitis, and low back pain.

3. Soft Tissue Injuries:

Duact proves valuable in addressing soft tissue injuries like sprains, strains, and post-operative pain.

4. Dysmenorrhoea:

For the treatment of dysmenorrhoea, Duact is a reliable choice.

5. Dental Pain:

Duact’s utility extends to the management of dental pain.

6. Cold & Fever:

Duact can also be employed for addressing cold and fever.

It is important to emphasize that this information may not be exhaustive, and consulting with a healthcare professional offers the most accurate guidance.

How Long Does It Take to Work?

The onset of Duact’s therapeutic effects typically ushers in a noticeable reduction in symptoms such as pain or fever. However, the anti-inflammatory actions may necessitate a longer duration, sometimes stretching over a week or more. Duact’s concentration in the bloodstream typically peaks within 1 to 2 hours. It is crucial to remember that individual experiences may exhibit variations, making consultation with a healthcare professional the preferred route for the most accurate information.

Drug Interactions

Duact Capsule has the potential to interact with other medications, influencing its effectiveness or augmenting the risk of side effects. Key considerations include:

1. Drug-Drug Interaction:

This scenario unfolds when a medication reacts with one or more other drugs, potentially influencing their respective actions.

2. Blood-Thinning Drugs with NSAIDs:

Individuals on blood-thinning medications may face an elevated risk of bleeding when using NSAIDs. Consequently, consultation with a healthcare provider is essential to explore safer over-the-counter pain relief options.

3. Alcohol Interaction:

Simultaneous consumption of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), and alcohol may contribute to gastrointestinal (GI) bleeding.

It is imperative to disclose all current medications to your healthcare provider, encompassing both prescription and over-the-counter drugs, vitamins, and herbal products. Such transparency facilitates the delivery of personalized insights based on your health status and medication profile.


Several precautions should be observed while employing Duact Capsule:

1. Age Considerations:

Duact is not recommended for children under 1 year. In adults, the dosage range spans from 0.9 to 2.4 g per day.

2. Alcohol Avoidance:

The simultaneous consumption of Duact and alcohol may give rise to gastrointestinal (GI) bleeding.

3. Renal Insufficiency:

For individuals with renal insufficiency or liver insufficiency, caution is advised due to the potential for an increased risk of adverse reactions.

4. Drug Interactions:

When other medications are concurrently used with Duact, there exists the possibility of drug interactions, necessitating vigilance.

For precise insights into these precautions, it is advisable to consult with a healthcare professional.


In summary, Duact Capsule emerges as a valuable therapeutic agent in the realm of allergic rhinitis management, backed by a precise composition and a well-defined set of indications. However, the prudent navigation of contraindications, vigilant monitoring of potential side effects, and an awareness of interactions and precautions ensure the safe and effective utilization of this medication. The journey to well-being is underpinned by informed decisions, in collaboration with healthcare professionals.

Key Information

Active Ingredients Akrivastin and Pseudoephedrine Hydrochloride
Indications Allergic Rhinitis
Dosage and Administration Adults and adolescents (12+): 1 capsule per day, up to 3 times a day if necessary, oral administration
Contraindications Hypersensitivity, severe hypertension, severe coronary artery disease, recent MAOI use, pheochromocytoma, age < 12, diabetes mellitus, hyperthyroidism, glaucoma, special populations with increased risk
Common Side Effects Dry mouth, headache, sleepiness, mild burning or stinging, itching or tingling
Less Common Side Effects Acid or sour stomach, belching, body aches or pain, congestion, cough, dryness or soreness of the throat, fever, heartburn, hoarseness, indigestion, lack or loss of strength, nausea, nervousness, runny nose, stomach discomfort, upset, or pain, tender, swollen glands in the neck, trouble sleeping, trouble swallowing, voice changes
Serious Side Effects Fast heart rate, pounding heartbeats, dizziness, faintness, or lightheadedness when changing positions
Interactions Avoid concomitant use with sympathomimetic drugs (decongestants, appetite suppressants, or amphetamine-like psychostimulants)
Onset of Action Reduction in symptoms such as pain or fever is typically noticeable, while anti-inflammatory effects may take a week or more
Elimination Half-Life Approximately 3.1-3.4 hours in patients with compromised liver function, leading to an estimated 15.5 to 17 hours for complete elimination
Benefits Treatment of Rheumatoid Arthritis, Ankylosing Spondylitis, Osteoarthritis, Non-Articular Rheumatic Conditions, Soft Tissue Injuries, Dysmenorrhoea, Dental Pain, Cold & Fever
How Long Does Duact Take to Work? Symptom reduction is typically noticeable, while anti-inflammatory effects may take a week or more. Blood levels peak at 1 to 2 hours
Drug Interactions Potential interactions with other medications, especially blood-thinning drugs, and possible alcohol interactions
Precautions Age considerations, alcohol avoidance, vigilance in renal insufficiency, liver insufficiency, and when used with other medications

1 review for Duact Capsule

  1. Shahlaa

    How much is this medicine per pack and where are you based?

    • Medical Guidance Center

      Hello Shahlaa, this is Wikikenko.

      The price of Duact Capsule may vary depending on the country and the pharmacy. you can log in to see up-to-date duact capsule price. WikiKenko, do not sell Duact Capsule.

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