Virosil Cream

Unlock the comprehensive insights into “Virosil Cream,” a topical medication that houses the potent aciclovir as its active ingredient. In this detailed guide, we explore the intricacies of this cream, shedding light on its functions, uses, side effects, precautions, and more.

Dosage form

Pack size


%5 10G



Generic Name (Ingredient)

Contains 50 Mg 5% W / W Acyclovir.

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At the core of Virosil Cream lies aciclovir, a synthetic purine nucleoside. Aciclovir exhibits remarkable inhibitory activity against both herpes simplex viruses (HSV-1 and HSV-2) and the varicella-zoster virus (VZV). Let’s delve into how this potent compound operates.

Mechanism of Action

Virosil Cream’s mode of action is highly selective, driven by its affinity for the enzyme thymidine kinase, encoded by HSV and VZV. This pivotal viral enzyme transforms Virosil into Virosil monophosphate, a nucleotide analogue. The monophosphate undergoes successive conversions into diphosphate and eventually triphosphate through cellular enzymes. In vitro, Virosil triphosphate orchestrates the cessation of herpes viral DNA replication through three mechanisms:

  1. Competitive inhibition of viral DNA polymerase.
  2. Incorporation into and termination of the growing viral DNA chain.
  3. Inactivation of the viral DNA polymerase.

What Virosil Cream Treats

Virosil Cream finds its niche in the treatment of various conditions, primarily revolving around herpes infections. Its applications encompass:

  • Herpes Simplex Dermatological Infections (Cold Sores)
  • Initial and Recurrent Genital Herpes
  • Herpes Labialis

Application of Virosil Cream

Virosil Cream is exclusively intended for external use. However, exercise caution not to apply it to sensitive areas such as the mouth, eyes, or vagina, as it may trigger irritation. Vigilance is key, particularly in avoiding contact with the eyes.

Side Effects

While using Virosil Cream, should any signs of an allergic reaction manifest (like rash, localized pain, or swelling), discontinue use and promptly notify your healthcare provider. It’s noteworthy that the cream incorporates cetearyl alcohol, which has the potential to induce local skin reactions, including contact dermatitis.


Individuals with severe immunodeficiency conditions, such as AIDS or those who have undergone bone marrow transplants, should consider oral forms of Virosil for treatment. It’s advisable to consult your healthcare provider when grappling with such conditions, ensuring a safe and effective approach to infection treatment.

Pregnancy and Breastfeeding

For expectant mothers or those contemplating pregnancy, it’s imperative to notify your healthcare provider. The use of Virosil during pregnancy should be a calculated decision, weighing potential benefits against risks. Should pregnancy be confirmed during treatment, immediate consultation with a healthcare professional or pharmacist is recommended.

Onset of Action

The specific onset of action for Virosil Cream is not explicitly outlined in available sources. The active ingredient, aciclovir, operates by halting the replication of herpes viral DNA through a multi-step process. This intricate mechanism may vary in duration, contingent on factors such as infection severity and individual health. Therefore, personalized information from a healthcare professional is paramount.


The dosage of Virosil Cream is contingent upon the nature and severity of the infection. Here are general guidelines:

  • Acute Herpes Zoster: 800 mg every 4 hours, 5 times daily for 7 to 10 days.
  • Genital Herpes:
    • Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days.
    • Chronic suppressive therapy for recurrent disease: 400 mg twice daily for up to 12 months.
    • Intermittent therapy: 200 mg every 4 hours, 5 times daily for 5 days.
  • Chickenpox:
    • Children (2 years of age and older): 20 mg/kg/dose 4 times daily (80 mg/kg/day) for 5 days.
    • Adults and Children (>40 kg): 800 mg 4 times daily for 5 days.

In cases of missed doses, administer the missed dose as soon as remembered and continue with the remaining doses for the day at evenly spaced intervals.


While specific storage conditions for Virosil Cream are not explicitly detailed in available sources, it’s generally advised to store medications in a cool, dry place away from direct light and heat. Remember to keep medications out of the reach of children. For precise storage instructions, consult the product packaging or a healthcare professional.


In conclusion, Virosil Cream stands as a valuable tool in the fight against herpes infections, driven by the potent aciclovir. This medication’s intricate mechanism of action ensures its selectivity in combatting viral replication. However, the multifaceted nature of Virosil Cream warrants diligent precaution and professional guidance. Your healthcare provider serves as a beacon of expertise to navigate the nuances of this medication effectively.

Key Information

Attribute Details
Generic Name Virosil Cream
Active Ingredient Aciclovir
Dosage Form Topical Cream


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


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