Petisel Injection Solution Iceren Ampul

In the realm of pain management, “Petisel Injection Solution” emerges as a formidable contender. This medication, available in the form of an injectable solution, offers hope to individuals grappling with severe pain. In this comprehensive guide, we delve into the nuances of Petisel, from its active ingredient to its uses and contraindications.

Dosage form

Pack size


100 Mg/2Ml 5X2Ml

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At the core of Petisel lies Pethidine hydrochloride, an opioid analgesic renowned for its efficacy in alleviating severe pain. This potent ingredient serves as the backbone of Petisel’s pain-relieving capabilities.

Other Composition

In addition to the active ingredient, Petisel incorporates essential elements to facilitate its administration. The composition includes water for injection, sodium hydroxide, and hydrochloric acid for pH adjustment. These components ensure the solution’s stability and suitability for various administration routes.


Petisel finds its application in diverse scenarios:

  1. Severe Pain with Multifaceted Origins: Petisel emerges as a reliable option for mitigating severe pain stemming from various causes.
  2. Gastrointestinal and Reproductive System Pain: It extends its pain-relieving influence to the gastrointestinal system and the pathways within the reproductive and excretory systems, with the exception of gall bladder and bile duct pain.
  3. Cardiac and Pulmonary Conditions: Petisel plays a crucial role in addressing heart attacks and pulmonary edema, underscoring its versatility.
  4. Preoperative Pain Management: It assumes the role of a preoperative pain reliever, aiding in the preparation for surgical procedures.
  5. Childbirth Assistance: Petisel contributes to more comfortable childbirth experiences by reducing pain, shortening the duration of specific uterine canal phases, addressing cervical stiffness and spasms, managing contractions, and alleviating headaches.

When Caution Is Warranted

While Petisel holds promise as a pain management solution, there are situations where its use is contraindicated:

  1. Hypersensitivity: Individuals displaying hypersensitivity to pethidine hydrochloride or related substances, particularly phenylpiperidine derivatives, should refrain from Petisel usage.
  2. Psychiatric Drug Interactions: Petisel should not be combined with psychiatric drugs, alcohol, painkillers, or other substances impacting the nervous system. Caution is crucial to avoid potential complications.
  3. MAO Inhibitor Interaction: Usage within 14 days after MAO inhibitor treatment, commonly employed in depression management, should be avoided.
  4. Procarbazine Contraindication: Petisel should not be employed in conjunction with procarbazine, a medication used in specific tumor treatments.
  5. Respiratory Sensitivity: In conditions where respiratory depression is to be evaded (e.g., respiratory failure, asthma, emphysema), Petisel use is discouraged.
  6. Alternative Pain Management: For cases involving nerve pain, migraines, and cough, alternative medications with lower addictive potential are recommended.
  7. Specific Health Conditions: Petisel is not suitable for individuals with severe hepatic failure, acute hepatic porphyria, post-gallbladder removal complications, or pancreatic inflammation. Additionally, it should be avoided in cases of traumatic head injuries and increased intracranial pressure, as well as instances of heart rhythm disturbance (Supraventricular dysrhythmia).

Petisel Interactions

Understanding potential interactions between medications is paramount for safe usage. Petisel, like all medications, has its share of interactions to consider. Here are key points to keep in mind:

  • Avoid Duplicate Active Ingredients: Concurrent use of medications sharing an active ingredient should be avoided to prevent side effects or overdose risks.
  • Dangerous Combinations: Certain medication combinations can prove hazardous. For instance, pairing a blood-thinning drug with a nonsteroidal anti-inflammatory drug (NSAID) elevates the risk of severe bleeding.
  • Petisel Specifics: Given that Petisel contains Pethidine hydrochloride, it should not be administered alongside psychiatric drugs, alcohol, painkillers, or substances affecting the nervous system. Furthermore, usage within 14 days following MAO inhibitor treatment or alongside procarbazine is discouraged.

However, this list is not exhaustive, and other potential interactions may exist. Consultation with a healthcare professional before commencing any new medication is imperative. Their expertise ensures personalized guidance considering your health status and medical history.

Pethidine During Pregnancy

The safety of Petisel usage during pregnancy is not explicitly outlined in available sources. It’s essential to recognize that all medications, particularly during the first trimester, can potentially impact the fetus. Some medications may also pass into breast milk, albeit in limited quantities. Consequently, consultation with a healthcare professional is vital before initiating any medication during pregnancy or while breastfeeding.

Their guidance, aligned with your health status and medical history, ensures safe and informed choices. Always adhere to the instructions provided by your healthcare provider or pharmacist when using any medication.

Exploring Non-Opioid Alternatives

For individuals seeking non-opioid alternatives for severe pain management, several options are available:

  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): These medications, including naproxen, ibuprofen, aspirin, diclofenac, celecoxib, meloxicam, and indomethacin, control pain by regulating prostaglandin production at infection or injury sites.
  • Acetaminophen: Commonly known as Tylenol, acetaminophen serves as a non-aspirin pain and fever reducer.
  • Muscle Relaxants: These aid in managing pain associated with muscle spasms.
  • Corticosteroids: Effective in reducing inflammation and addressing chronic pain.
  • Anticonvulsants and Antidepressants: These medications find utility in neuropathic pain management.
  • Local Anesthetics: Employed for targeted numbing of specific body areas.
  • Exercise Therapy and Physical Therapy: Non-pharmacological treatments that improve pain and functionality.
  • Interventional Therapies: Incorporating injections and procedures directly addressing pain sources.

The effectiveness of these alternatives hinges on the specific type and cause of pain. Consultation with a healthcare professional remains paramount before embarking on any new pain management strategy. In the realm of pain relief, knowledge and prudence are the cornerstones of well-being.

At a glance

Property Details
Active Ingredient Pethidine hydrochloride
Composition Water for injection<br>Sodium hydroxide and hydrochloric acid for pH adjustment
Indications for Use – Severe pain with multifaceted origins<br>- Gastrointestinal and reproductive system pain<br>- Cardiac and pulmonary conditions<br>- Preoperative pain management<br>- Childbirth assistance
Contraindications – Hypersensitivity to pethidine hydrochloride or related substances<br>- Psychiatric drug interactions<br>- MAO inhibitor treatment within 14 days<br>- Procarbazine usage<br>- Respiratory sensitivity<br>- Certain health conditions
Medication Interactions Be cautious of interactions, especially with substances affecting the nervous system or following MAO inhibitor treatment. Avoid duplicate active ingredients.
Pregnancy Considerations Consult a healthcare professional before using Petisel during pregnancy or while breastfeeding.
Non-Opioid Alternatives Explore non-opioid alternatives for pain management under healthcare professional guidance.


In the realm of pain management, Petisel Injection Solution stands as a formidable ally. Its efficacy in mitigating severe pain is complemented by a comprehensive understanding of its active ingredient, composition, applications, contraindications, and potential interactions. However, the judicious use of Petisel under the guidance of a healthcare professional is essential to unlock its benefits while mitigating risks. Knowledge, informed choices, and healthcare expertise pave the path to effective pain management and improved well-being.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
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