Depalex Xr Uzun Etkili Film Tablet 500 Mg

Depalex XR, a long-acting film tablet renowned for its efficacy, is a medication that holds a pivotal role in the management of epilepsy and bipolar disorders. In this in-depth guide, we’ll delve into the essential aspects of Depalex XR, including its composition, recommended dosages, potential side effects, and considerations for pregnant or breastfeeding individuals.

Dosage form

Pack size


500 Mg



Generic Name (Ingredient)

On A Fissile Tablet Equivalent To 500 Mg Sodium Valproate: Sodium Valproate 333.0 Mg Valproic Acid 145.0 Mg

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Unveiling Depalex XR

Depalex XR is a pharmaceutical wonder, with each 500 mg tablet containing sodium valproate activity equivalent to 333 mg of sodium valproate and 145 mg of valproic acid. This potent combination classifies it as an antiepileptic drug, primarily employed in the treatment of epilepsy.

Its mechanism of action involves calming the brain, rendering it effective against various types of epilepsy. Additionally, Depalex XR extends its therapeutic reach by being a valuable asset in managing mania associated with bipolar disorders. Furthermore, it serves as maintenance therapy for patients who positively respond to treatment.

One remarkable feature of Depalex XR is its long-acting formulation, allowing for convenient once-daily dosing. This characteristic is particularly advantageous in epilepsy cases where seizure control has been successfully achieved.


Depalex XR presents itself as a distinctive white, notched oblong film-coated tablet. For ease of access and preservation, it is meticulously packaged in Al/Al blister packs.

Precautions and Contraindications

While Depalex XR offers immense therapeutic potential, it’s essential to exercise caution and adhere to contraindications. This medication should not be used under the following circumstances:

  • If you have an allergy to any of its ingredients.
  • In the presence of acute or chronic liver inflammation.
  • In cases of severe liver inflammation due to medication use.
  • If you have the rare metabolic disease called porphyria.
  • In individuals with metabolic disorders that can elevate blood ammonia levels.
  • If you have a history of pancreatitis.

Furthermore, caution should be exercised when considering concurrent use of Depalex XR with mefloquine, a medication employed in malaria treatment, or lamotrigine, a drug prescribed for epilepsy.

Side Effects

As with any medication, Depalex XR has the potential to induce side effects. If you encounter any of the following symptoms, immediate medical attention is warranted:

  • Hives
  • Fever
  • Swollen glands
  • Mouth sores
  • Difficulty breathing
  • Swelling of your face, lips, tongue, or throat

These symptoms may signify an allergic reaction to Depalex XR. In case of any additional questions or concerns regarding potential side effects, it is advisable to seek guidance from a healthcare provider, who can provide detailed information and advice.

Recommended Dosage

The recommended dosage of Depalex XR hinges on the condition being treated. For epilepsy management, the usual dosage parameters are as follows:

  • Initiate with a daily dose of 600 mg.
  • Increase by 200 mg at three-day intervals until seizure control is attained.
  • Typically, this falls within the dosage range of 1,000 mg to 2,000 mg per day, or 20-30 mg/kg body weight.
  • If optimal control remains elusive within this range, the dosage may be further increased to 2,500 mg per day.

For individuals grappling with mania associated with bipolar disorders, the initial dosage mirrors that of epilepsy management:

  • Commence with 600 mg daily.
  • Increment by 200 mg/day at three-day intervals until control is established.
  • Generally, this falls within the range of 1,000 to 2,000 mg/day (or 20 to 30 mg/kg/day).

It is crucial to acknowledge that the recommended dosage can fluctuate based on individual factors such as age, weight, and the individual’s response to treatment. To ensure the utmost safety and efficacy, consulting a healthcare provider for personalized dosing guidance is paramount.

Depalex XR and Pregnancy/Breastfeeding

Depalex XR, encompassing sodium valproate and valproic acid, plays a pivotal role in managing epilepsy and bipolar disorders. However, it is imperative to engage in a thorough consultation with a healthcare professional before considering its use during pregnancy or while breastfeeding.

Some recommendations advise against breastfeeding during valproate therapy. Infants should undergo monitoring for jaundice and signs of liver damage due to the risk of Depalex XR-induced hepatotoxicity. Personalized recommendations and detailed information should always be sought from a healthcare provider to make informed decisions.


Depalex XR, with its long-acting formulation and multifaceted applications in epilepsy and bipolar disorders, emerges as a vital pharmaceutical asset. Its composition, precautions, and recommended dosages underscore the importance of professional medical guidance in its usage. When considering Depalex XR, it’s paramount to prioritize safety and seek clarification from healthcare providers regarding any questions or uncertainties.

This comprehensive guide aims to empower individuals with essential knowledge to make informed decisions about Depalex XR’s usage.


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The information on this page is not intended to be a substitute for professional medical advice, diagnosis, or treatment. always seek the advice for your physician or another qualified health provider with any questions you may have regarding a medical condition. Always remember to

  1. Ask your own doctor for medical advice.
  2. Names, brands, and dosage may differ between countries.
  3. When not feeling well, or experiencing side effects always contact your own doctor.


The truth is that when we’re sick, or worried about getting sick, the internet won’t help.

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If diagnoses could be made simply from a textbook or an article on a website, we would all be doctors and treat ourselves. Nothing can replace the experience and knowledge of specially trained people. As in any field, in medicine there are unscrupulous specialists, differences of opinion, inaccurate diagnoses and incorrect test results.


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